| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007381
BDB007381
|
BDBM170301
CC(C)NC(=O)N1CC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
|
C30H36Cl2FN5O3 604.554000 |
QSLDKSASSTYODR-ZWXBAZLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170301
|
Local ready
Direct docking supported
|
|
E3L007382
BDB007382
|
BDBM170302
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CN(CCO)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C28H33Cl2FN4O3 563.501000 |
NQOWOHHFNIRIJQ-WZRJCJTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170302
|
Local ready
Direct docking supported
|
|
E3L007383
BDB007383
|
BDBM170303
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CN(C(=O)NC3CCCCC3)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C33H40Cl2FN5O3 644.619000 |
DTWGQRJFPSEIOM-KZDQUIMASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170303
|
Local ready
Direct docking supported
|
|
E3L007384
BDB007384
|
BDBM170304
CC(=O)OC(C)(C)C(=O)N1CC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
|
C32H37Cl2FN4O5 647.575000 |
GAWPYTPNGOIQDW-ODXNXTLBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170304
|
Local ready
Direct docking supported
|
|
E3L007385
BDB007385
|
BDBM170305
CC(=O)N1CC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
|
C28H31Cl2FN4O3 561.485000 |
PMMNFMGFQYSRTE-WZRJCJTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170305; PubChem:CID69927604
|
Local ready
Direct docking supported
|
|
E3L007386
BDB007386
|
BDBM170306
CCCCNC(=O)N1CC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
|
C31H38Cl2FN5O3 618.581000 |
UNMXSYQWFIMBED-IUXWYWOJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170306
|
Local ready
Direct docking supported
|
|
E3L007387
BDB007387
|
BDBM170307
CCN(CC)C(=O)N1CC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)C1
|
C31H38Cl2FN5O3 618.581000 |
ANPDJWHIUYONOC-IUXWYWOJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170307
|
Local ready
Direct docking supported
|
|
E3L007388
BDB007388
|
BDBM170308
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(OC(=O)CN)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C31H37Cl2FN4O4 619.565000 |
PMIPZOPYEPYDBH-OGBWVMALSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170308
|
Local ready
Direct docking supported
|
|
E3L007389
BDB007389
|
BDBM170309
CC(C)[C@H](N)C(=O)OC1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C34H43Cl2FN4O4 661.646000 |
PCKWZFJFZKRZJN-SGUUMDGVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170309
|
Local ready
Direct docking supported
|
|
E3L007390
BDB007390
|
BDBM170310
CC(C)C[C@H](N)C(=O)OC1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C35H45Cl2FN4O4 675.673000 |
UYHLRILAHNMBPG-XSXVMKGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170310
|
Local ready
Direct docking supported
|
|
E3L007391
BDB007391
|
BDBM170311
CC[C@H](C)[C@H](N)C(=O)OC1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C35H45Cl2FN4O4 675.673000 |
FKSNZSZSJXYTNP-HYDRXBKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170311
|
Local ready
Direct docking supported
|
|
E3L007392
BDB007392
|
BDBM170312
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(OC(=O)[C@@H](N)Cc3ccccc3)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C38H43Cl2FN4O4 709.690000 |
KFOMAXVKJYLIHN-RGUYMSHQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170312
|
Local ready
Direct docking supported
|
|
E3L007393
BDB007393
|
BDBM170313
CC(C)[C@@H](N)C(=O)OC1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C34H43Cl2FN4O4 661.646000 |
PCKWZFJFZKRZJN-GGHFKMNMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170313
|
Local ready
Direct docking supported
|
|
E3L007394
BDB007394
|
BDBM170314
C[C@@H](N)C(=O)OC1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C32H39Cl2FN4O4 633.592000 |
NSAFCVYUZIQKHJ-LMIVATOFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170314
|
Local ready
Direct docking supported
|
|
E3L007395
BDB007395
|
BDBM170315
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(OC(=O)C(C)(C)N)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C33H41Cl2FN4O4 647.619000 |
CCBWZZYXLQJFDQ-HQDKQNMLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170315
|
Local ready
Direct docking supported
|
|
E3L007396
BDB007396
|
BDBM170317
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCc2ccccc2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C30H30Cl2FN3O4 586.491000 |
RTQJVGCHWMYJCR-QMSAFVIYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170317; PubChem:CID69927668
|
Local ready
Direct docking supported
|
|
E3L007397
BDB007397
|
BDBM170318
CCC[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C25H28Cl2FN3O4 524.420000 |
AXMHDGDAXHHFHE-BPTJMKCRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170318; PubChem:CID69926747
|
Local ready
Direct docking supported
|
|
E3L007398
BDB007398
|
BDBM170319
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCc2cccs2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C28H28Cl2FN3O4S 592.520000 |
WHKHDURMIVZMPI-USJLZIQHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170319
|
Local ready
Direct docking supported
|
|
E3L007399
BDB007399
|
BDBM170320
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCCc2ccccc2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C31H32Cl2FN3O4 600.518000 |
BCFRJDRPMVPRNN-IMYDKJEWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170320; PubChem:CID69927250
|
Local ready
Direct docking supported
|
|
E3L007400
BDB007400
|
BDBM170321
CC(C)CC[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C27H32Cl2FN3O4 552.474000 |
JUQUXOAGDHDFKM-JMTGUGMLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170321; PubChem:CID69927211
|
Local ready
Direct docking supported
|