| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007421
BDB007421
|
BDBM170350
CC(C)CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C32H40ClF3N4O3 621.144000 |
WMMAOMZOXIRAAB-IUIQULDGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170350
|
Local ready
Direct docking supported
|
|
E3L007422
BDB007422
|
BDBM170351
CC(C)CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H37Cl2F2N3O4 612.545000 |
BWXWKPPKCMVJHG-QISNEAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170351
|
Local ready
Direct docking supported
|
|
E3L007423
BDB007423
|
BDBM170352
CC(C)CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C30H37ClF3N3O4 596.090000 |
BDWPNDHQTXTDID-QISNEAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170352
|
Local ready
Direct docking supported
|
|
E3L007424
BDB007424
|
BDBM170353
CC(C)CC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C31H39Cl2F2N3O4 626.572000 |
RGGASZWTQWAWAZ-KOXXDOIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170353
|
Local ready
Direct docking supported
|
|
E3L007425
BDB007425
|
BDBM170354
CC(C)CC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C31H39ClF3N3O4 610.117000 |
IZGWHHZJJAPUBL-KOXXDOIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170354
|
Local ready
Direct docking supported
|
|
E3L007426
BDB007426
|
BDBM170355
CC(C)CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C30H38ClF2N3O4 578.100000 |
QOHWWKAFAGBURH-OPMYFTJMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170355; PubChem:CID69928075
|
Local ready
Direct docking supported
|
|
E3L007427
BDB007427
|
BDBM170356
CC(C)CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2ccc(F)c(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C30H37ClF3N3O4 596.090000 |
RVRPEZPMUKBEJU-UTOFGKABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170356
|
Local ready
Direct docking supported
|
|
E3L007428
BDB007428
|
BDBM170357
CC(C)CC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C31H40ClF2N3O4 592.127000 |
MQWCQUCGCWNIAO-RFHZMROGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170357
|
Local ready
Direct docking supported
|
|
E3L007429
BDB007429
|
BDBM170358
CC(C)CC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2ccc(F)c(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C31H39ClF3N3O4 610.117000 |
JUJQYMGJIIFXSF-DDJVEYHLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170358
|
Local ready
Direct docking supported
|
|
E3L007430
BDB007430
|
BDBM170359
CC(C)(C)C[C@H]1N[C@@H](C(=O)N2CCN(C(=O)C3CC3)CC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C31H35Cl2FN4O3 601.550000 |
QPTYFYSXLDMOJD-ANKKVJNISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170359
|
Local ready
Direct docking supported
|
|
E3L007431
BDB007431
|
US9079913, MI-743B
CC(C)(C)C[C@H]1N[C@@H](C(=O)N2CCN(C(=O)C3CC3)CC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)N(C(=O)C1CC1)c1cc(Cl)c(F)cc12
|
C35H39Cl2FN4O4 669.625000 |
UEKYYLCINSYWHM-XMUPGDTHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170360; PubChem:CID58254334
|
Local ready
Direct docking supported
|
|
E3L007432
BDB007432
|
BDBM170362
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H]2CC[C@@H](O)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C30H36Cl2FN3O3 576.540000 |
AEJRFQRMYCKSKQ-NEOZLGHSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170362
|
Local ready
Direct docking supported
|
|
E3L007433
BDB007433
|
BDBM170363
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCC2CCC(O)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C30H36Cl2FN3O3 576.540000 |
AEJRFQRMYCKSKQ-WDCAOUMESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170363
|
Local ready
Direct docking supported
|
|
E3L007434
BDB007434
|
BDBM170364
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](Cc2ccccc2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C28H35ClFN3O4 532.056000 |
OXZIJQNIPHNIKE-VNDJSJTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170364; PubChem:CID89770398
|
Local ready
Direct docking supported
|
|
E3L007435
BDB007435
|
BDBM170365
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC[C@H](O)[C@H](O)CO)[C@H](Cc2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C28H34Cl2FN3O5 582.500000 |
MEFLJCTUKXWPAO-NQXAXKLISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170365
|
Local ready
Direct docking supported
|
|
E3L007436
BDB007436
|
BDBM170366
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CN)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C27H33Cl2FN4O3 551.490000 |
CHOOPCQVUSZOHF-NVHWNKAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170366
|
Local ready
Direct docking supported
|
|
E3L007437
BDB007437
|
BDBM170367
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)COC(=O)CC(=O)O)[C@H](c2ccc(F)c(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H33Cl2F2N3O7 656.510000 |
QHPRLXJFFKKKPL-MBLQSPPPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170367
|
Local ready
Direct docking supported
|
|
E3L007438
BDB007438
|
BDBM170368
CCOP(=O)(OCC)OC[C@@H](O)CCNC(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1ccc(F)c(Cl)c1
|
C31H40Cl2F2N3O7P 706.551000 |
LVYJQIAVQPOJFR-DDJVEYHLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170368
|
Local ready
Direct docking supported
|
|
E3L007439
BDB007439
|
BDBM170369
CN(C)C[C@@H](O)CCNC(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1ccc(F)c(Cl)c1
|
C29H36Cl2F2N4O3 597.534000 |
CJYSCRMRQVIJQR-CWEXNXMASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170369
|
Local ready
Direct docking supported
|
|
E3L007440
BDB007440
|
BDBM170370
CN(CC[C@H](O)CO)C(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C28H34Cl2FN3O4 566.501000 |
QUSDLRJJENDOQR-FKUBJEGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170370
|
Local ready
Direct docking supported
|