| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L009961
BDB009961
|
BDBM218191
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1C
|
C27H26F3N5O2 509.532000 |
QIIWMJZOLWTVDS-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218191; PubChem:CID90324954
|
Local ready
Direct docking supported
|
|
E3L009962
BDB009962
|
BDBM218192
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4ccccc4c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C29H24F3N5O2 531.538000 |
VGWUPBXKWTZOSE-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218192; PubChem:CID90324957
|
Local ready
Direct docking supported
|
|
E3L009963
BDB009963
|
BDBM218194
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(F)c(Cl)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H22ClF4N5O2 547.940000 |
OVUAPQVGAUZHPY-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218194; PubChem:CID90317930
|
Local ready
Direct docking supported
|
|
E3L009964
BDB009964
|
BDBM218197
Cc1cccc(C)c1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H26F3N5O2 509.532000 |
DYNITNWINGFQFP-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218197; PubChem:CID90324953
|
Local ready
Direct docking supported
|
|
E3L009965
BDB009965
|
BDBM218198
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(Cl)ccc3Cl)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H22Cl2F3N5O2 564.395000 |
BFNVMFCUNLDJMB-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218198; PubChem:CID90318435
|
Local ready
Direct docking supported
|
|
E3L009966
BDB009966
|
BDBM218199
COc1cc(C#N)cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H25F3N6O3 550.541000 |
TWQILPBHUMKDOF-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218199; PubChem:CID90324951
|
Local ready
Direct docking supported
|
|
E3L009967
BDB009967
|
BDBM218201
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1F
|
C26H23F4N5O2 513.495000 |
NQUUGRDCMBGMED-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218201; PubChem:CID90325545
|
Local ready
Direct docking supported
|
|
E3L009968
BDB009968
|
BDBM218203
COc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1Cl
|
C26H23ClF3N5O3 545.949000 |
RPAPAIHAPJOZAU-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218203; PubChem:CID90319784
|
Local ready
Direct docking supported
|
|
E3L009969
BDB009969
|
BDBM218205
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(OC(F)F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H24F5N5O3 561.511000 |
AKJDKAWCYHAZCG-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218205; PubChem:CID90325544
|
Local ready
Direct docking supported
|
|
E3L009970
BDB009970
|
BDBM218207
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(F)cc3F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H22F5N5O2 531.485000 |
JVLNYYMRKFGKNZ-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218207; PubChem:CID90325546
|
Local ready
Direct docking supported
|
|
E3L009971
BDB009971
|
BDBM218209
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4ncccc4c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C28H23F3N6O2 532.526000 |
XZHNRPIVKFBZAR-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218209; PubChem:CID90325547
|
Local ready
Direct docking supported
|
|
E3L009972
BDB009972
|
BDBM218210
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cnc(N(C)C)nc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H25F3N8O2 526.523000 |
GRBXYKRBJHQYGZ-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218210; PubChem:CID90325548
|
Local ready
Direct docking supported
|
|
E3L009973
BDB009973
|
BDBM218211
COc1cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)ccn1
|
C25H23F3N6O3 512.492000 |
RRSRZHGOILTTEX-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218211; PubChem:CID90318224
|
Local ready
Direct docking supported
|
|
E3L009974
BDB009974
|
BDBM218213
CCOc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cn1
|
C26H25F3N6O3 526.519000 |
WIROEGWRHDWMRV-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218213; PubChem:CID90325616
|
Local ready
Direct docking supported
|
|
E3L009975
BDB009975
|
BDBM218215
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(F)c3F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H20F5N5O2 517.458000 |
VWJZCIXRGFKLCM-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218215; PubChem:CID90325603
|
Local ready
Direct docking supported
|
|
E3L009976
BDB009976
|
BDBM218217
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4c(c3)CCC4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C28H26F3N5O2 521.543000 |
PKWTXOHWSKBLIL-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218217; PubChem:CID90325612
|
Local ready
Direct docking supported
|
|
E3L009977
BDB009977
|
BDBM218219
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(Br)cc3F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H20BrF4N5O2 578.364000 |
YZYDVCMEUIPOIN-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218219; PubChem:CID90318762
|
Local ready
Direct docking supported
|
|
E3L009978
BDB009978
|
BDBM218221
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(Cl)c(Cl)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H22Cl2F3N5O2 564.395000 |
DEUFQSQHJZQORB-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218221; PubChem:CID90318738
|
Local ready
Direct docking supported
|
|
E3L009979
BDB009979
|
BDBM218223
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccncc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H23F3N6O2 496.493000 |
WUXNPDHVEQBRHN-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218223; PubChem:CID90325604
|
Local ready
Direct docking supported
|
|
E3L009980
BDB009980
|
BDBM218274
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccccc3C(N)=O)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C26H23F3N6O3 524.503000 |
QNTDNOLBFNYJNP-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218274; PubChem:CID90325609
|
Local ready
Direct docking supported
|