| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010021
BDB010021
|
BDBM218645
CCOc1ccccc1Cn1c(-c2cccc(C)c2)nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c21
|
C28H31N5O3 485.588000 |
SCVFEYGYKQDRBF-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218645; PubChem:CID90325052
|
Local ready
Direct docking supported
|
|
E3L010022
BDB010022
|
BDBM218649
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(C)C)cc2)c1
|
C28H31N5O2 469.589000 |
XBAAZGRSJOUBLB-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218649; PubChem:CID90325054
|
Local ready
Direct docking supported
|
|
E3L010023
BDB010023
|
BDBM218655
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(OC(F)(F)F)cc2)c1
|
C26H24F3N5O3 511.504000 |
RINLKIPNFNZWFI-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218655; PubChem:CID90325055
|
Local ready
Direct docking supported
|
|
E3L010024
BDB010024
|
BDBM218662
Cc1cccc(-c2nc3c(n2Cc2ccc(C(F)(F)F)c(F)c2)C(N[C@H](C)C2CC2)NC(C(=O)O)=N3)c1
|
C26H25F4N5O2 515.511000 |
PYCUGXUUUDZMCT-CKAQCJTGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218662; PubChem:CID118566467
|
Local ready
Direct docking supported
|
|
E3L010025
BDB010025
|
BDBM218664
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C3CC3)cc2)c1
|
C29H31N5O2 481.600000 |
AXWOYXAQLUXWOL-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218664; PubChem:CID90325605
|
Local ready
Direct docking supported
|
|
E3L010026
BDB010026
|
BDBM218670
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(Cl)cc2Cl)c1
|
C26H25Cl2N5O2 510.425000 |
MGDGAHMTVZXGJU-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218670; PubChem:CID90325606
|
Local ready
Direct docking supported
|
|
E3L010027
BDB010027
|
BDBM218717
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2Cl)c1
|
C27H25ClF3N5O2 543.977000 |
CKBWZGLTPUBSID-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218717; PubChem:CID90325594
|
Local ready
Direct docking supported
|
|
E3L010028
BDB010028
|
BDBM218827
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(OC(F)F)cc2)c1
|
C27H27F2N5O3 507.541000 |
MQYLPSRKSKGDEG-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218827; PubChem:CID90325589
|
Local ready
Direct docking supported
|
|
E3L010029
BDB010029
|
BDBM218830
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(OC(F)(F)F)c(F)c2)c1
|
C27H25F4N5O3 543.521000 |
AEFOSCMRSIJAHS-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218830; PubChem:CID90318091
|
Local ready
Direct docking supported
|
|
E3L010030
BDB010030
|
Tatb-fxii618 (15)
CSCC(=O)N1CN(C(=O)CSC)CN(C(=O)CSC)C1
|
C12H21N3O3S3 351.519000 |
SESLACGWCLIGCW-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM218838; PubChem:CID124222759
|
Local ready
Direct docking supported
|
|
E3L010031
BDB010031
|
Tbmt-PK15 (12)
CSCc1nc(CSC)nc(CSC)n1
|
C9H15N3S3 261.441000 |
LLRKYJLGNJXILI-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM218839; PubChem:CID124222760
|
Local ready
Direct docking supported
|
|
E3L010032
BDB010032
|
Tata-fxii618 (14)
CSCCC(=O)N1CN(C(=O)CCSC)CN(C(=O)CCSC)C1
|
C15H27N3O3S3 393.600000 |
XNEWOOABUWKDES-UHFFFAOYSA-N | P00748 | Coagulation factor XII |
BindingDB, PubChem
BindingDB:BDBM218840; PubChem:CID124222761
|
Local ready
Direct docking supported
|
|
E3L010033
BDB010033
|
BDBM220104
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)c(Cl)c2)c1
|
C26H23ClF3N5O2 529.950000 |
JSLSOLQCFRWQRL-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220104; PubChem:CID90325586
|
Local ready
Direct docking supported
|
|
E3L010034
BDB010034
|
BDBM220105
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccccc2C(F)(F)F)c1
|
C26H24F3N5O2 495.505000 |
XZGZYRRWQXUNOS-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220105; PubChem:CID90325595
|
Local ready
Direct docking supported
|
|
E3L010035
BDB010035
|
BDBM220106
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2F)c1
|
C27H25F4N5O2 527.522000 |
CXLPSYBXRDCUKJ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220106; PubChem:CID90318894
|
Local ready
Direct docking supported
|
|
E3L010036
BDB010036
|
BDBM220107
CCOc1cc(C(F)(F)F)ccc1Cn1c(-c2cccc(C)c2)nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c21
|
C29H30F3N5O3 553.585000 |
OIHBGIATOOEKBM-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220107; PubChem:CID118558766
|
Local ready
Direct docking supported
|
|
E3L010037
BDB010037
|
BDBM220108
COc1ccc(Cn2c(-c3cccc(C)c3)nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c32)cc1
|
C27H29N5O3 471.561000 |
ZBSNSHYAYWFGHV-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220108; PubChem:CID90324976
|
Local ready
Direct docking supported
|
|
E3L010038
BDB010038
|
BDBM220109
CCc1ccc(Cn2c(-c3cccc(C)c3)nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c32)cc1
|
C27H29N5O2 455.562000 |
IKQNLAADZLDFTK-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220109; PubChem:CID118558564
|
Local ready
Direct docking supported
|
|
E3L010039
BDB010039
|
BDBM220110
Cc1ccc(Cn2c(-c3cccc(C)c3)nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c32)cc1
|
C26H27N5O2 441.535000 |
NVHRWPIQGXLONM-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220110; PubChem:CID90318643
|
Local ready
Direct docking supported
|
|
E3L010040
BDB010040
|
BDBM220112
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(Cl)cc2)c1
|
C26H26ClN5O2 475.980000 |
KBRKFDISYCAOJB-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220112; PubChem:CID90325061
|
Local ready
Direct docking supported
|