| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010001
BDB010001
|
BDBM218425
Cc1ccc(OCCCO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(Cl)cc2)c1
|
C29H32ClN5O4 550.059000 |
FFIAACRUHUWRNF-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218425; PubChem:CID118558588
|
Local ready
Direct docking supported
|
|
E3L010002
BDB010002
|
BDBM218426
CCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(Cl)cc1
|
C27H28ClN5O3 506.006000 |
HVCKZOLOACTIED-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218426; PubChem:CID90325392
|
Local ready
Direct docking supported
|
|
E3L010003
BDB010003
|
BDBM218428
COCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(Cl)cc1
|
C29H32ClN5O4 550.059000 |
UUYFPJVZEDIYOE-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218428; PubChem:CID90325391
|
Local ready
Direct docking supported
|
|
E3L010004
BDB010004
|
BDBM218494
COCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(Cl)cc1
|
C28H30ClN5O4 536.032000 |
NFWIVUIZPWPYMC-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218494; PubChem:CID90317801
|
Local ready
Direct docking supported
|
|
E3L010005
BDB010005
|
BDBM218495
Cc1ccc(OCCO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C27H28ClN5O4 522.005000 |
IFVSVRPPDNZZAM-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218495; PubChem:CID90325161
|
Local ready
Direct docking supported
|
|
E3L010006
BDB010006
|
BDBM218496
Cc1ccc(OCCC(=O)O)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C28H28ClN5O5 550.015000 |
PDDKMGULZLSBLE-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218496; PubChem:CID90325614
|
Local ready
Direct docking supported
|
|
E3L010007
BDB010007
|
BDBM218521
Cc1ccc(OCCC(=O)NCCO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C30H33ClN6O5 593.084000 |
RLEIOIUDLIVZBC-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218521; PubChem:CID90325610
|
Local ready
Direct docking supported
|
|
E3L010008
BDB010008
|
BDBM218522
CNC(=O)CCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(Cl)cc1
|
C29H31ClN6O4 563.058000 |
MBDUBWZNUGPXSI-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218522; PubChem:CID90325591
|
Local ready
Direct docking supported
|
|
E3L010009
BDB010009
|
BDBM218552
Cc1ccc(OCCCN2CCOCC2)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C32H37ClN6O4 605.139000 |
FMSBOOLGJBBUKI-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218552; PubChem:CID90325620
|
Local ready
Direct docking supported
|
|
E3L010010
BDB010010
|
BDBM218565
COCCN(CCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(Cl)cc1)CCOC
|
C34H43ClN6O5 651.208000 |
FJXJRALJUZMHSS-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218565; PubChem:CID90317874
|
Local ready
Direct docking supported
|
|
E3L010011
BDB010011
|
BDBM218572
Cc1ccc(OCCCO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C#N)cc2)c1
|
C29H30N6O4 526.597000 |
VYPCGHIXKZVEFQ-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218572; PubChem:CID90325037
|
Local ready
Direct docking supported
|
|
E3L010012
BDB010012
|
BDBM218576
Cc1ccc(OCCCN2CCN(C)CC2)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C33H40ClN7O3 618.182000 |
GSAKZFZWVCBHRV-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218576; PubChem:CID90325031
|
Local ready
Direct docking supported
|
|
E3L010013
BDB010013
|
BDBM218577
Cc1ccc(O)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C25H24ClN5O3 477.952000 |
NASPEUGUIIYJAA-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218577; PubChem:CID136632738
|
Local ready
Direct docking supported
|
|
E3L010014
BDB010014
|
BDBM218578
Cc1ccc(OCC(O)CO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C28H30ClN5O5 552.031000 |
ZLINCHVBRDXZJS-QRIPLOBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218578; PubChem:CID90318235
|
Local ready
Direct docking supported
|
|
E3L010015
BDB010015
|
BDBM218594
Cc1ccc(OCCCO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(Cl)cc2)c1
|
C28H30ClN5O4 536.032000 |
FHPSGAHPAGBDCF-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218594; PubChem:CID90318177
|
Local ready
Direct docking supported
|
|
E3L010016
BDB010016
|
BDBM218595
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2C(C)c2ccc(Cl)cc2)c1
|
C26H26ClN5O2 475.980000 |
RFIQWDYELQSAFG-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218595; PubChem:CID90318034
|
Local ready
Direct docking supported
|
|
E3L010017
BDB010017
|
BDBM218596
Cc1cccc(-c2nc3nc(C(=O)O)nc(NCC4CC4)c3n2C(C)c2ccc(Cl)cc2)c1
|
C25H24ClN5O2 461.953000 |
SVPIXLNJNWQONY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218596; PubChem:CID90318378
|
Local ready
Direct docking supported
|
|
E3L010018
BDB010018
|
BDBM218604
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@@H](C)C4CC4)c3n2C(C)c2ccc(Cl)cc2)c1
|
C26H26ClN5O2 475.980000 |
RFIQWDYELQSAFG-VYRBHSGPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218604; PubChem:CID90318454
|
Local ready
Direct docking supported
|
|
E3L010019
BDB010019
|
BDBM218605
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(F)c(C(F)(F)F)c2)c1
|
C26H23F4N5O2 513.495000 |
ZIDZYYAWURFFNQ-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218605; PubChem:CID90325051
|
Local ready
Direct docking supported
|
|
E3L010020
BDB010020
|
BDBM218631
Cc1cccc(-c2nc3nc(C(=O)O)nc4c3n2Cc2cc(C(F)(F)F)ccc2OCC2CC2[C@@H](C)N4)c1
|
C27H24F3N5O3 523.515000 |
AUCWQFKTNOLLSY-ZCGYKAAXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218631; PubChem:CID118566466
|
Local ready
Direct docking supported
|