| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010081
BDB010081
|
BDBM220261
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@@H](C)c4ccc(Cl)cc4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H23ClF3N5O2 565.983000 |
JITFOZQDOZFHBB-KRWDZBQOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220261; PubChem:CID90318451
|
Local ready
Direct docking supported
|
|
E3L010082
BDB010082
|
BDBM220262
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C(C)(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H28F3N5O2 511.548000 |
RTAIJZFVCRNVRQ-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220262; PubChem:CID90324979
|
Local ready
Direct docking supported
|
|
E3L010083
BDB010083
|
BDBM220263
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H26F3N5O2 497.521000 |
LIYYWAXIZLMFQT-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220263; PubChem:CID90324980
|
Local ready
Direct docking supported
|
|
E3L010084
BDB010084
|
BDBM220264
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@@H](C)C(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H26F3N5O2 497.521000 |
LIYYWAXIZLMFQT-INIZCTEOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220264; PubChem:CID90324982
|
Local ready
Direct docking supported
|
|
E3L010085
BDB010085
|
BDBM220265
Cc1cccc(-c2nc3nc(C(=O)O)nc(NCC4CCCCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O2 523.559000 |
CEGPVPCDMIUYQE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220265; PubChem:CID90318077
|
Local ready
Direct docking supported
|
|
E3L010086
BDB010086
|
BDBM220266
CCN(CC)c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C25H24F3N5O2 483.494000 |
PKRBNQUPZRULOH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220266; PubChem:CID90318672
|
Local ready
Direct docking supported
|
|
E3L010087
BDB010087
|
BDBM220267
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C4CC4)C(F)(F)F)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H21F6N5O2 549.475000 |
VRMVONAFRKIKOU-LJQANCHMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220267; PubChem:CID90325067
|
Local ready
Direct docking supported
|
|
E3L010088
BDB010088
|
BDBM220268
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@@H](C4CC4)C(F)(F)F)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H21F6N5O2 549.475000 |
VRMVONAFRKIKOU-IBGZPJMESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220268; PubChem:CID118558767
|
Local ready
Direct docking supported
|
|
E3L010089
BDB010089
|
BDBM220269
CC[C@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H31F3N6O2 552.601000 |
OZEKBIYAVYVMSQ-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220269; PubChem:CID90318851
|
Local ready
Direct docking supported
|
|
E3L010090
BDB010090
|
BDBM220270
CC[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H31F3N6O2 552.601000 |
OZEKBIYAVYVMSQ-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220270; PubChem:CID90318453
|
Local ready
Direct docking supported
|
|
E3L010091
BDB010091
|
BDBM220271
COc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3(C)C)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H30F3N5O3 553.585000 |
RHSHBIMIROHIKP-QRIPLOBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220271; PubChem:CID90325065
|
Local ready
Direct docking supported
|
|
E3L010092
BDB010092
|
BDBM220272
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@@H](c4ccccc4)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C33H31F3N6O2 600.645000 |
FINLGEULGOVMAL-SANMLTNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220272; PubChem:CID90318770
|
Local ready
Direct docking supported
|
|
E3L010093
BDB010093
|
BDBM220273
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](c4ccccc4)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C33H31F3N6O2 600.645000 |
FINLGEULGOVMAL-AREMUKBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220273; PubChem:CID90317990
|
Local ready
Direct docking supported
|
|
E3L010094
BDB010094
|
BDBM220274
CCN(C)c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C24H22F3N5O2 469.467000 |
PSHJMKFBGVEADE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220274; PubChem:CID90318406
|
Local ready
Direct docking supported
|
|
E3L010095
BDB010095
|
BDBM220275
CC[C@@H](C)Nc1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C25H24F3N5O2 483.494000 |
RSTGVYFGLXAZSX-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220275; PubChem:CID90325613
|
Local ready
Direct docking supported
|
|
E3L010096
BDB010096
|
BDBM220278
CCC(C)CNc1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C26H26F3N5O2 497.521000 |
MCGBSRRPYRRZPC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220278; PubChem:CID90317847
|
Local ready
Direct docking supported
|
|
E3L010097
BDB010097
|
BDBM220279
CCCC(CCC)Nc1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C28H30F3N5O2 525.575000 |
WTRQWFJSGXEDRP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220279; PubChem:CID90318196
|
Local ready
Direct docking supported
|
|
E3L010098
BDB010098
|
Mivebresib
CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1
|
C22H19F2N3O4S 459.474000 |
RDONXGFGWSSFMY-UHFFFAOYSA-N | O15164, Q09472, Q92831 | Histone acetyltransferase p300, Transcription intermediary factor 1-alpha, Histone acetyltransferase KAT2B |
BindingDB, PubChem
BindingDB:BDBM220447; PubChem:CID71600087
|
Local ready
Direct docking supported
|
|
E3L010099
BDB010099
|
BDBM220538
CCCCN(CCC)c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C28H30F3N5O2 525.575000 |
SYXCOHLQTZTPCK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220538; PubChem:CID90317728
|
Local ready
Direct docking supported
|
|
E3L010100
BDB010100
|
BDBM220544
CCCN(CC)c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C26H26F3N5O2 497.521000 |
WPMFQRGILGQRDI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220544; PubChem:CID90318179
|
Local ready
Direct docking supported
|