| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L009981
BDB009981
|
BDBM218289
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccccc3C(F)(F)F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H23F6N5O2 563.502000 |
VPUVJGGCCIKOJB-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218289; PubChem:CID90325359
|
Local ready
Direct docking supported
|
|
E3L009982
BDB009982
|
BDBM218290
CCc1ccc(OC)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H30F3N5O3 553.585000 |
MBDRBVWHXZSRLZ-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218290; PubChem:CID90325360
|
Local ready
Direct docking supported
|
|
E3L009983
BDB009983
|
BDBM218295
CCc1ccccc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H28F3N5O2 523.559000 |
VFLYNCUKUXYMJP-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218295; PubChem:CID90325363
|
Local ready
Direct docking supported
|
|
E3L009984
BDB009984
|
BDBM218297
CCc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H30F3N5O2 537.586000 |
IRJVEQPNGLGYPM-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218297; PubChem:CID90325361
|
Local ready
Direct docking supported
|
|
E3L009985
BDB009985
|
BDBM218298
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cnn(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C24H24F3N7O2 499.497000 |
CYTGWVNSEHQKHS-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218298; PubChem:CID90319597
|
Local ready
Direct docking supported
|
|
E3L009986
BDB009986
|
BDBM218302
Cc1noc(C)c1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C25H25F3N6O3 514.508000 |
OWAKOTDIXVBIGZ-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218302; PubChem:CID90318022
|
Local ready
Direct docking supported
|
|
E3L009987
BDB009987
|
BDBM218313
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3nccn3C)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C24H24F3N7O2 499.497000 |
YVTNTPOCURPKIU-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218313; PubChem:CID90319378
|
Local ready
Direct docking supported
|
|
E3L009988
BDB009988
|
BDBM218314
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)n1
|
C27H28F3N7O2 539.562000 |
RITMFXTXKZTBJF-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218314; PubChem:CID90324963
|
Local ready
Direct docking supported
|
|
E3L009989
BDB009989
|
BDBM218320
CC(C)c1cnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)s1
|
C26H27F3N6O2S 544.603000 |
GNMKQNHEKKHDHH-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218320; PubChem:CID90324960
|
Local ready
Direct docking supported
|
|
E3L009990
BDB009990
|
BDBM218323
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ncccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C24H22F3N7O2 497.481000 |
GKTOCAYFDCUKBQ-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218323; PubChem:CID90324961
|
Local ready
Direct docking supported
|
|
E3L009991
BDB009991
|
BDBM218325
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ncco3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C23H21F3N6O3 486.454000 |
IEFKEMCOVAWYKH-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218325; PubChem:CID90325366
|
Local ready
Direct docking supported
|
|
E3L009992
BDB009992
|
BDBM218327
CC(C)c1csc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)n1
|
C26H27F3N6O2S 544.603000 |
KFVMYNJAHHIKKO-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218327; PubChem:CID90325365
|
Local ready
Direct docking supported
|
|
E3L009993
BDB009993
|
BDBM218328
Cc1cnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)s1
|
C24H23F3N6O2S 516.549000 |
RPXFXBIQHPYQTR-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218328; PubChem:CID90318767
|
Local ready
Direct docking supported
|
|
E3L009994
BDB009994
|
BDBM218338
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3nccs3)n(Cc3ccc(Cl)cc3)c12)C1CC1
|
C21H19ClN6O2S 454.943000 |
BVDBXIDWCMRYKY-LLVKDONJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218338; PubChem:CID90319971
|
Local ready
Direct docking supported
|
|
E3L009995
BDB009995
|
BDBM218344
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3nccs3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C23H21F3N6O2S 502.522000 |
HVWFYOJNCYBOAT-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218344; PubChem:CID90325364
|
Local ready
Direct docking supported
|
|
E3L009996
BDB009996
|
BDBM218347
CCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(Cl)cc1
|
C28H30ClN5O3 520.033000 |
ZSJODYUUULRJKC-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218347; PubChem:CID90325185
|
Local ready
Direct docking supported
|
|
E3L009997
BDB009997
|
BDBM218373
Cc1ccc(C)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(Cl)cc2)c1
|
C27H28ClN5O2 490.007000 |
LFYZLWLULVIDSX-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218373; PubChem:CID90318440
|
Local ready
Direct docking supported
|
|
E3L009998
BDB009998
|
BDBM218374
C=CCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(Cl)cc1
|
C29H30ClN5O3 532.044000 |
LWJIQOHCKQSOSZ-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218374; PubChem:CID90325038
|
Local ready
Direct docking supported
|
|
E3L009999
BDB009999
|
BDBM218382
COCCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(Cl)cc1
|
C30H34ClN5O4 564.086000 |
FPSYLUXVKFYGSM-LJQANCHMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218382; PubChem:CID90325182
|
Local ready
Direct docking supported
|
|
E3L010000
BDB010000
|
BDBM218411
COCCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(Cl)cc1
|
C29H32ClN5O4 550.059000 |
MOYGSHUSGUJZBM-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218411; PubChem:CID90318223
|
Local ready
Direct docking supported
|