| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010141
BDB010141
|
BDBM221488
CC1CN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)CCO1
|
C25H29F3N6O3 518.540000 |
JOOLHEYIZIUCAP-YSSOQSIOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221488; PubChem:CID90324995
|
Local ready
Direct docking supported
|
|
E3L010142
BDB010142
|
BDBM221489
C[C@@H](Nc1nc(C(=O)O)nc2nc(Nc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H25F3N6O2 510.520000 |
CNAWIRCNWFFFBX-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221489; PubChem:CID90324992
|
Local ready
Direct docking supported
|
|
E3L010143
BDB010143
|
BDBM221490
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC(c4ccccc4)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O3 580.611000 |
LVBUZJPLTGJKIP-FKSKYRLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221490; PubChem:CID90324997
|
Local ready
Direct docking supported
|
|
E3L010144
BDB010144
|
BDBM221491
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC(C(F)(F)F)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H26F6N6O3 572.510000 |
SVWLIGYLGTZSCS-FWJOYPJLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221491; PubChem:CID90324996
|
Local ready
Direct docking supported
|
|
E3L010145
BDB010145
|
BDBM221492
COCC1CN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)CCO1
|
C26H31F3N6O4 548.566000 |
GDNIZRQTPWQRBT-NYRJJRHWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221492; PubChem:CID90324993
|
Local ready
Direct docking supported
|
|
E3L010146
BDB010146
|
BDBM221493
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC4(CCCC4)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H33F3N6O3 558.605000 |
XDIBZQUMXKHDQC-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221493; PubChem:CID90325634
|
Local ready
Direct docking supported
|
|
E3L010147
BDB010147
|
BDBM221494
C#CCC1CN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)CCO1
|
C27H29F3N6O3 542.562000 |
OCFOYJFKTIDPDS-QRIPLOBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221494; PubChem:CID90325611
|
Local ready
Direct docking supported
|
|
E3L010148
BDB010148
|
BDBM221495
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3C[C@H]4C[C@@H]3CO4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H27F3N6O3 516.524000 |
DZEBUUOYYMVTDI-FSPWUOQZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221495; PubChem:CID90325630
|
Local ready
Direct docking supported
|
|
E3L010149
BDB010149
|
BDBM221496
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@@H]3C)n(Cc3ccc(Cl)cc3)c12)C1CC1
|
C23H27ClN6O3 470.961000 |
VHWIPQVFSLCDMV-UONOGXRCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221496; PubChem:CID90325627
|
Local ready
Direct docking supported
|
|
E3L010150
BDB010150
|
BDBM221497
C[C@@H](Nc1ncnc2nc(N[C@@H](CO)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H29F3N6O 510.564000 |
CILXIHWCIWXIDQ-VGSWGCGISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221497; PubChem:CID90318535
|
Local ready
Direct docking supported
|
|
E3L010151
BDB010151
|
BDBM221498
CC(Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1cccnc1
|
C27H28F3N7O2 539.562000 |
HCHZJGMJCDNLEL-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221498; PubChem:CID90318449
|
Local ready
Direct docking supported
|
|
E3L010152
BDB010152
|
BDBM221499
CC(Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1ccccn1
|
C27H28F3N7O2 539.562000 |
HBWSXGBBYWULPR-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221499; PubChem:CID90318914
|
Local ready
Direct docking supported
|
|
E3L010153
BDB010153
|
BDBM221500
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@@H]3C)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H29F3N6O3 518.540000 |
PCANFLMOEKOEJO-LSDHHAIUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221500; PubChem:CID90318299
|
Local ready
Direct docking supported
|
|
E3L010154
BDB010154
|
BDBM221501
C[C@@H]1COCCN1c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C25H29F3N6O3 518.540000 |
PCANFLMOEKOEJO-HUUCEWRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221501; PubChem:CID90318743
|
Local ready
Direct docking supported
|
|
E3L010155
BDB010155
|
BDBM221502
CC[C@H](Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1ccccc1
|
C29H31F3N6O2 552.601000 |
HIYNGUONAJHUKM-VGSWGCGISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221502; PubChem:CID118558528
|
Local ready
Direct docking supported
|
|
E3L010156
BDB010156
|
BDBM221503
C[C@@H](Nc1nc(C(=O)O)nc2nc(N(C)[C@@H](C)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H31F3N6O2 552.601000 |
RWDLEBZTCAYYOZ-MSOLQXFVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221503; PubChem:CID90325475
|
Local ready
Direct docking supported
|
|
E3L010157
BDB010157
|
BDBM221504
C[C@@H](Nc1nc(C(=O)O)nc2nc(NC(=O)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H25F3N6O3 538.530000 |
PRULCRHVJAKXOS-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221504; PubChem:CID90325470
|
Local ready
Direct docking supported
|
|
E3L010158
BDB010158
|
BDBM221505
C[C@H](Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1cccc(F)c1
|
C28H28F4N6O2 556.564000 |
GWGXZFOLSIVCDV-CVEARBPZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221505; PubChem:CID90325474
|
Local ready
Direct docking supported
|
|
E3L010159
BDB010159
|
BDBM221506
CC1CCCN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)C1
|
C26H31F3N6O2 516.568000 |
SSCYSKWCZAWTCI-OEMAIJDKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221506; PubChem:CID90318551
|
Local ready
Direct docking supported
|
|
E3L010160
BDB010160
|
BDBM221507
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC(c4ccccc4)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H33F3N6O2 578.639000 |
HACFEQSBIJUQGT-HWYAHNCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221507; PubChem:CID90317711
|
Local ready
Direct docking supported
|