| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010121
BDB010121
|
BDBM221468
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2N)c1
|
C28H30F3N7O2 553.589000 |
UVTXIGRMOCTEDE-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221468; PubChem:CID90318431
|
Local ready
Direct docking supported
|
|
E3L010122
BDB010122
|
BDBM221469
C[C@H](Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1ccc(F)cc1
|
C28H28F4N6O2 556.564000 |
RVSQWYWJCJCCCP-CVEARBPZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221469; PubChem:CID90325206
|
Local ready
Direct docking supported
|
|
E3L010123
BDB010123
|
BDBM221470
C[C@@H](Nc1nc(C(=O)O)nc2nc(N(C)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H27F3N6O2 524.547000 |
URKVPMIOBVMUGO-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221470; PubChem:CID90318745
|
Local ready
Direct docking supported
|
|
E3L010124
BDB010124
|
BDBM221471
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3Cc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H35F3N6O2 592.666000 |
ARZKPKITNJVOTN-VGOKPJQXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221471; PubChem:CID90325207
|
Local ready
Direct docking supported
|
|
E3L010125
BDB010125
|
BDBM221472
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(Cc3ccc(Cl)c(F)c3)c12)C1CCC1
|
C30H30ClFN8O3 605.074000 |
WNTSSWMQMGJUBQ-HXOBKFHXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221472; PubChem:CID136632471
|
Local ready
Direct docking supported
|
|
E3L010126
BDB010126
|
BDBM221473
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCN(C)CC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C24H28F3N7O2 503.529000 |
HVALXMWLPATETM-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221473; PubChem:CID90318381
|
Local ready
Direct docking supported
|
|
E3L010127
BDB010127
|
BDBM221474
C[C@@H](Nc1nc(C(=O)O)nc2nc(N[C@@H](CO)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H29F3N6O3 554.573000 |
VUCORYCZTBOMBO-IERDGZPVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221474; PubChem:CID90325071
|
Local ready
Direct docking supported
|
|
E3L010128
BDB010128
|
BDBM221475
C[C@H](CO)Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C23H27F3N6O3 492.502000 |
KTDIYIBRNXDKCP-CHWSQXEVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221475; PubChem:CID90325068
|
Local ready
Direct docking supported
|
|
E3L010129
BDB010129
|
BDBM221476
C[C@@H](Nc1nc(C(=O)O)nc2nc(N[C@H](CO)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H29F3N6O3 554.573000 |
VUCORYCZTBOMBO-IIBYNOLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221476; PubChem:CID90325070
|
Local ready
Direct docking supported
|
|
E3L010130
BDB010130
|
BDBM221477
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOCC3)n(Cc3ccc(Cl)cc3)c12)C1CC1
|
C22H25ClN6O3 456.934000 |
KHKQIUHYIGVAER-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221477; PubChem:CID90318490
|
Local ready
Direct docking supported
|
|
E3L010131
BDB010131
|
BDBM221478
C[C@@H](CO)Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C23H27F3N6O3 492.502000 |
KTDIYIBRNXDKCP-QWHCGFSZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221478; PubChem:CID90318478
|
Local ready
Direct docking supported
|
|
E3L010132
BDB010132
|
BDBM221479
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H29F3N6O2 502.541000 |
REZUKVHJMDOXBW-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221479; PubChem:CID90325069
|
Local ready
Direct docking supported
|
|
E3L010133
BDB010133
|
BDBM221480
C[C@@H](Nc1nc(C(=O)O)nc2nc(NC3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H31F3N6O2 516.568000 |
KDEHZFCQSLNCCK-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221480; PubChem:CID90325212
|
Local ready
Direct docking supported
|
|
E3L010134
BDB010134
|
BDBM221481
C[C@@H](Nc1nc(C(=O)O)nc2nc(NCc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H27F3N6O2 524.547000 |
CIYJGEILZJNTKF-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221481; PubChem:CID90325233
|
Local ready
Direct docking supported
|
|
E3L010135
BDB010135
|
BDBM221482
C[C@@H](Nc1nc(C(=O)O)nc2nc(N(C)Cc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H29F3N6O2 538.574000 |
IMUSZOWIYDUGPM-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221482; PubChem:CID90318169
|
Local ready
Direct docking supported
|
|
E3L010136
BDB010136
|
BDBM221483
C[C@@H](Nc1nc(C(=O)O)nc2nc(N(C)C3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H33F3N6O2 530.595000 |
LNCCMJYKYARTAY-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221483; PubChem:CID90325219
|
Local ready
Direct docking supported
|
|
E3L010137
BDB010137
|
BDBM221484
C[C@H](Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1ccccc1
|
C28H29F3N6O2 538.574000 |
UBJYYTZEBYXWAU-SJORKVTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221484; PubChem:CID90325208
|
Local ready
Direct docking supported
|
|
E3L010138
BDB010138
|
BDBM221485
C[C@@H](Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1ccccc1
|
C28H29F3N6O2 538.574000 |
UBJYYTZEBYXWAU-IAGOWNOFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221485; PubChem:CID90318181
|
Local ready
Direct docking supported
|
|
E3L010139
BDB010139
|
BDBM221486
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC(C)(C)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H31F3N6O3 532.567000 |
PLQFHBWINTVIQD-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221486; PubChem:CID90325213
|
Local ready
Direct docking supported
|
|
E3L010140
BDB010140
|
BDBM221487
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CC(C)(C)OC(C)(C)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H35F3N6O3 560.621000 |
PWVMAEFKTHKXTQ-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221487; PubChem:CID90324994
|
Local ready
Direct docking supported
|