| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010101
BDB010101
|
BDBM220865
Cc1cccc(-c2nc3nc(C(=O)O)nc(N(C)CC(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H26F3N5O2 497.521000 |
KECLNRNMCLERBN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM220865; PubChem:CID90317626
|
Local ready
Direct docking supported
|
|
E3L010102
BDB010102
|
BDBM221047
Cc1cccc(-c2nc3nc(C(=O)O)nc(NC(C)C(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H26F3N5O2 497.521000 |
LIYYWAXIZLMFQT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221047; PubChem:CID90319485
|
Local ready
Direct docking supported
|
|
E3L010103
BDB010103
|
Sphinx31
O=C(Nc1cc(C(F)(F)F)ccc1N1CCN(Cc2ccccn2)CC1)c1ccc(-c2ccncc2)o1
|
C27H24F3N5O2 507.516000 |
VURLRACCOCGFDB-UHFFFAOYSA-N | Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
BindingDB, PubChem
BindingDB:BDBM221074; PubChem:CID91972002
|
Local ready
Direct docking supported
|
|
E3L010104
BDB010104
|
BDBM221237
Cc1cccc(-c2nc3nc(C(=O)O)nc(NC(C)C(C)(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H28F3N5O2 511.548000 |
RTAIJZFVCRNVRQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221237; PubChem:CID90325623
|
Local ready
Direct docking supported
|
|
E3L010105
BDB010105
|
BDBM221238
Cc1cccc(-c2nc3nc(C(=O)O)nc(NCC4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H24F3N5O2 495.505000 |
DCZNMMAXMURFES-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221238; PubChem:CID90317810
|
Local ready
Direct docking supported
|
|
E3L010106
BDB010106
|
BDBM221239
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCCO)C4CCC4)c3n2Cc2ccc(Cl)cc2)c1
|
C28H30ClN5O3 520.033000 |
OUTOFKRCRTXTBS-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221239; PubChem:CID90318339
|
Local ready
Direct docking supported
|
|
E3L010107
BDB010107
|
BDBM221447
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCCO)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N5O3 553.585000 |
KKYWVIIEMCZVPQ-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221447; PubChem:CID90325064
|
Local ready
Direct docking supported
|
|
E3L010108
BDB010108
|
BDBM221454
Cc1cccc(-c2nc3ncnc(N[C@H](CCCO)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H30F3N5O 509.576000 |
UDBOTJMBRARKPX-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221454; PubChem:CID90317872
|
Local ready
Direct docking supported
|
|
E3L010109
BDB010109
|
BDBM221455
CCC[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H30F3N5O2 537.586000 |
IYGVDKXKWUPPAV-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221455; PubChem:CID90318484
|
Local ready
Direct docking supported
|
|
E3L010110
BDB010110
|
BDBM221456
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCC(=O)NCCO)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C31H33F3N6O4 610.637000 |
MSFUMPYFROHSHS-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221456; PubChem:CID118558814
|
Local ready
Direct docking supported
|
|
E3L010111
BDB010111
|
BDBM221457
Cc1cccc(-c2nc3nc(C(=O)O)nc(N4CCC[C@@H]4C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H28F3N5O2 535.570000 |
YJKYVHSYOAOEFI-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221457; PubChem:CID90318789
|
Local ready
Direct docking supported
|
|
E3L010112
BDB010112
|
BDBM221458
Cc1cccc(-c2nc3ncnc(N4CCC[C@@H]4C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5 491.561000 |
PNUZBLIBTXBUPP-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221458; PubChem:CID90317702
|
Local ready
Direct docking supported
|
|
E3L010113
BDB010113
|
BDBM221459
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCCN4CCN(C)CC4)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C34H40F3N7O2 635.735000 |
SAWDZWCUKLYYBL-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221459; PubChem:CID90318336
|
Local ready
Direct docking supported
|
|
E3L010114
BDB010114
|
BDBM221460
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCCN(C)C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C31H35F3N6O2 580.655000 |
LCSXLEHGDRLSAB-XMMPIXPASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221460; PubChem:CID90317641
|
Local ready
Direct docking supported
|
|
E3L010115
BDB010115
|
BDBM221461
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCC(N)=O)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H29F3N6O3 566.584000 |
LVVGYDRZBZSCRX-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221461; PubChem:CID90317974
|
Local ready
Direct docking supported
|
|
E3L010116
BDB010116
|
BDBM221462
CNC(=O)CC[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O3 580.611000 |
JLNJKPSLPNIUAH-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221462; PubChem:CID90325593
|
Local ready
Direct docking supported
|
|
E3L010117
BDB010117
|
BDBM221463
Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CC(O)CO)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N5O4 569.584000 |
HIUXYTNJMDAACU-FOIFJWKZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221463; PubChem:CID90318531
|
Local ready
Direct docking supported
|
|
E3L010118
BDB010118
|
BDBM221465
COc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC(F)(F)C3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H26F5N5O3 575.538000 |
OENJDSYCZSCONR-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221465; PubChem:CID90325203
|
Local ready
Direct docking supported
|
|
E3L010119
BDB010119
|
BDBM221466
COc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(NC(C)C3CC(C)C3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H30F3N5O3 553.585000 |
DRGJMOZHSPYPFJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221466; PubChem:CID90318111
|
Local ready
Direct docking supported
|
|
E3L010120
BDB010120
|
BDBM221467
COc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3(F)F)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H24F5N5O3 561.511000 |
DSQVIAZJGHDMJC-IKJXHCRLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221467; PubChem:CID90325621
|
Local ready
Direct docking supported
|