| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010161
BDB010161
|
BDBM221508
CC(C)CC(=O)Nc1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C25H29F3N6O3 518.540000 |
SZSHBATUGFKWTI-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221508; PubChem:CID90318155
|
Local ready
Direct docking supported
|
|
E3L010162
BDB010162
|
BDBM221509
C[C@@H](Nc1nc(C(=O)O)nc2nc(NC(=O)C3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H31F3N6O3 544.578000 |
XYLAQQXPJGQPCS-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221509; PubChem:CID90325220
|
Local ready
Direct docking supported
|
|
E3L010163
BDB010163
|
BDBM221510
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H33F3N6O2 578.639000 |
SFLNTGXSHSRWMQ-PHSANKKPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221510; PubChem:CID90325218
|
Local ready
Direct docking supported
|
|
E3L010164
BDB010164
|
BDBM221511
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC(C)(C)C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H33F3N6O2 530.595000 |
JXJPFOFDLGTIHV-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221511; PubChem:CID90318348
|
Local ready
Direct docking supported
|
|
E3L010165
BDB010165
|
BDBM221512
CC(C)C1CCCN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)C1
|
C28H35F3N6O2 544.622000 |
HWFYQMQWMPUXLC-DIAVIDTQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221512; PubChem:CID90325075
|
Local ready
Direct docking supported
|
|
E3L010166
BDB010166
|
BDBM221514
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccccc3)n(Cc3ccc(C(F)(F)F)c(F)c3)c12)C1CCC1
|
C31H32F4N6O2 596.629000 |
MRPAFWOBMOAUGY-QFADGXAASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221514; PubChem:CID90325073
|
Local ready
Direct docking supported
|
|
E3L010167
BDB010167
|
BDBM221515
CCCN(c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)[C@@H](C)c1ccccc1
|
C31H35F3N6O2 580.655000 |
XMAAVVTUAVHOBW-UXHICEINSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221515; PubChem:CID90325072
|
Local ready
Direct docking supported
|
|
E3L010168
BDB010168
|
BDBM221516
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O3 580.611000 |
LSBWIAKFVFQASP-JPYJTQIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221516; PubChem:CID90325076
|
Local ready
Direct docking supported
|
|
E3L010169
BDB010169
|
BDBM221536
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O3 580.611000 |
LSBWIAKFVFQASP-WZONZLPQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221536; PubChem:CID90318932
|
Local ready
Direct docking supported
|
|
E3L010170
BDB010170
|
BDBM221680
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O2 564.612000 |
GGVYFLFTMZSDDI-FKSKYRLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221680; PubChem:CID90318401
|
Local ready
Direct docking supported
|
|
E3L010171
BDB010171
|
BDBM221682
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H32F3N7O2 579.627000 |
HEJQXUJIETURET-FKSKYRLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221682; PubChem:CID90318601
|
Local ready
Direct docking supported
|
|
E3L010172
BDB010172
|
BDBM221687
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCC3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H29F3N6O2 550.585000 |
MDSTWEIDNQJJLK-PLEWWHCXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221687; PubChem:CID90318322
|
Local ready
Direct docking supported
|
|
E3L010173
BDB010173
|
BDBM221693
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOCC3c3ccccc3)n(Cc3ccc(C(F)(F)F)c(F)c3)c12)C1CCC1
|
C31H30F4N8O3 638.626000 |
ILWMDUVWANWQHF-LIXIDFRTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221693; PubChem:CID136632431
|
Local ready
Direct docking supported
|
|
E3L010174
BDB010174
|
BDBM221697
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H31F3N8O3 620.636000 |
VWSJJNFRCXESKD-JPYJTQIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221697; PubChem:CID136632657
|
Local ready
Direct docking supported
|
|
E3L010175
BDB010175
|
BDBM221700
CC[C@@H](c1ccccc1)N(C)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C30H33F3N6O2 566.628000 |
BPULDNLATADUJH-JPYJTQIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221700; PubChem:CID90324999
|
Local ready
Direct docking supported
|
|
E3L010176
BDB010176
|
BDBM221701
Cc1cc(C)n(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)n1
|
C25H26F3N7O2 513.524000 |
DEVPRFUNLBUDBI-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221701; PubChem:CID90318115
|
Local ready
Direct docking supported
|
|
E3L010177
BDB010177
|
BDBM221702
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC3c3cccc(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H30F4N6O2 582.602000 |
AOFCVULZYGZTNB-LIXIDFRTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221702; PubChem:CID90325000
|
Local ready
Direct docking supported
|
|
E3L010178
BDB010178
|
BDBM221703
Cc1cc(-c2ccccc2)nn1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C30H28F3N7O2 575.595000 |
MIIUEHHYRGDJPK-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221703; PubChem:CID90318072
|
Local ready
Direct docking supported
|
|
E3L010179
BDB010179
|
BDBM221704
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC[C@@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H33F3N6O2 578.639000 |
SFLNTGXSHSRWMQ-NTKDMRAZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221704; PubChem:CID90324998
|
Local ready
Direct docking supported
|
|
E3L010180
BDB010180
|
BDBM221712
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC[C@H]3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H33F3N6O2 578.639000 |
SFLNTGXSHSRWMQ-DVECYGJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221712; PubChem:CID90318705
|
Local ready
Direct docking supported
|