| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010181
BDB010181
|
BDBM221720
CC(C)CC1COCCN1c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H35F3N6O3 560.621000 |
YTHWEHBSYOOBJK-OQHSHRKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221720; PubChem:CID90325080
|
Local ready
Direct docking supported
|
|
E3L010182
BDB010182
|
BDBM221721
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCCC3c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H33F3N8O2 618.664000 |
BKUIYOXCLFAKHW-PHSANKKPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221721; PubChem:CID136632597
|
Local ready
Direct docking supported
|
|
E3L010183
BDB010183
|
BDBM221722
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3Cc3cccc(C(F)(F)F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C33H34F6N6O2 660.663000 |
NUTZLOBJSZPDNO-OEPVSBQMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221722; PubChem:CID90318394
|
Local ready
Direct docking supported
|
|
E3L010184
BDB010184
|
BDBM221723
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3Cc3ccc(F)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H34F4N6O2 610.656000 |
DABCXWWKGLAICJ-OEPVSBQMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221723; PubChem:CID90318686
|
Local ready
Direct docking supported
|
|
E3L010185
BDB010185
|
BDBM221724
COc1ccc(C2CCCCN2c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1
|
C32H35F3N6O3 608.665000 |
ZCEIYEGFLKGBGF-OEPVSBQMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221724; PubChem:CID90325473
|
Local ready
Direct docking supported
|
|
E3L010186
BDB010186
|
BDBM221726
CCC(c1ccccc1)N(C)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)c(F)c1
|
C31H32F4N8O2 624.643000 |
ZPGZTBRRECNURD-LIXIDFRTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221726; PubChem:CID136632430
|
Local ready
Direct docking supported
|
|
E3L010187
BDB010187
|
BDBM221731
CC(c1ccccn1)N(C)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)c(F)c1
|
C29H29F4N9O2 611.604000 |
WHWNCRQPPZYWFA-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221731; PubChem:CID136632449
|
Local ready
Direct docking supported
|
|
E3L010188
BDB010188
|
BDBM221732
CC(c1cccc(F)c1)N(C)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)c(F)c1
|
C30H29F5N8O2 628.606000 |
PHQQBORPFUZZQD-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221732; PubChem:CID136632695
|
Local ready
Direct docking supported
|
|
E3L010189
BDB010189
|
BDBM221733
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC34CCc3ccccc34)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H33F3N6O2 590.650000 |
BKTQNXIOZHXKIW-MFUYNUFSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221733; PubChem:CID90325477
|
Local ready
Direct docking supported
|
|
E3L010190
BDB010190
|
BDBM221734
CC(Nc1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)c1ccccn1
|
C28H28F3N9O2 579.587000 |
UYJBVYHOUCUUFQ-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221734; PubChem:CID136632696
|
Local ready
Direct docking supported
|
|
E3L010191
BDB010191
|
BDBM221735
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3C4CCC3COC4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H29F3N6O3 530.551000 |
NZFMFDGGUYPMCB-FTXHTYHOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221735; PubChem:CID90325643
|
Local ready
Direct docking supported
|
|
E3L010192
BDB010192
|
BDBM221739
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3C4CCCC3CC4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H31F3N6O2 528.579000 |
ZDGKAEJIXBUPJJ-APMMTJHUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221739; PubChem:CID90325649
|
Local ready
Direct docking supported
|
|
E3L010193
BDB010193
|
BDBM221742
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3[C@@H]4CC[C@H]3C[C@H](c3ccccc3)C4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C33H35F3N6O2 604.677000 |
ZOBKTXMTHZHUPD-DHJQOYHCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM221742
|
Local ready
Direct docking supported
|
|
E3L010194
BDB010194
|
BDBM221746
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3[C@@H]4CC[C@H]3C[C@H](Oc3ccc(Cl)c(F)c3)C4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C33H33ClF4N6O3 673.111000 |
SPKIUJRFUOHMDQ-RSZNVJGZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM221746
|
Local ready
Direct docking supported
|
|
E3L010195
BDB010195
|
BDBM221748
CC(C)CN(C)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C26H31F3N8O2 544.582000 |
LCGRKADIEBBRDM-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221748; PubChem:CID136954957
|
Local ready
Direct docking supported
|
|
E3L010196
BDB010196
|
BDBM221749
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N(C)C3CCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H31F3N8O2 556.593000 |
ZCFUVOVTJMAXMI-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221749; PubChem:CID136632746
|
Local ready
Direct docking supported
|
|
E3L010197
BDB010197
|
BDBM221750
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCC3(C)C)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H31F3N8O2 556.593000 |
KUGBEQCHQJOOFK-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221750; PubChem:CID136632747
|
Local ready
Direct docking supported
|
|
E3L010198
BDB010198
|
BDBM221751
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N(C)CC(C)(C)C)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H33F3N8O2 558.609000 |
RHFHKIXGXFDQML-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221751; PubChem:CID136954978
|
Local ready
Direct docking supported
|
|
E3L010199
BDB010199
|
BDBM221753
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCCC34CC4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H31F3N8O2 568.604000 |
RQBCRQJFKRHRAJ-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221753; PubChem:CID136954987
|
Local ready
Direct docking supported
|
|
E3L010200
BDB010200
|
BDBM221754
CC(C)C1CCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H33F3N8O2 570.620000 |
RGPHXFYABYWRGJ-QRIPLOBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221754; PubChem:CID136632748
|
Local ready
Direct docking supported
|