| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L017861
BDB017861
|
US10544132, Example 18
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(C#N)CC1)c1ccc(Cl)cc1
|
C29H26Cl2N2O3 521.444000 |
CHHGWWCMCGHFMJ-GDLZYMKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427065; PubChem:CID135281503
|
Local ready
Direct docking supported
|
|
E3L017862
BDB017862
|
US10544132, Example 19
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CNS(C)(=O)=O)CC1)c1ccc(Cl)cc1
|
C30H32Cl2N2O5S 603.568000 |
FDNNWFOMKUDPQB-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427066; PubChem:CID135281434
|
Local ready
Direct docking supported
|
|
E3L017863
BDB017863
|
BDBM427067
C#Cc1ccc(CN2C(=O)c3cc(C(C)(C)O)ccc3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C31H30ClNO4 516.037000 |
LTEBUYNLVXWZOS-WJOKGBTCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427067; PubChem:CID135281739
|
Local ready
Direct docking supported
|
|
E3L017864
BDB017864
|
US10544132, Example 21
C#Cc1ccc(CN2C(=O)c3cc(C(C)(C)O)cc(F)c3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C31H29ClFNO4 534.027000 |
NBPAQCMFLGCFBK-WJOKGBTCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427068; PubChem:CID135281734
|
Local ready
Direct docking supported
|
|
E3L017865
BDB017865
|
US10544132, Example 22
C#Cc1ccc(CN2C(=O)c3cc([C@@](C)(O)CO)cc(F)c3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C31H29ClFNO5 550.026000 |
LDOCNQIRVXHZQU-IGYGKHONSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427069; PubChem:CID154732955
|
Local ready
Direct docking supported
|
|
E3L017866
BDB017866
|
US10544132, Example 25
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H29ClN2O4 517.025000 |
KUYDFZZMIJDWQY-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427071; PubChem:CID135281419
|
Local ready
Direct docking supported
|
|
E3L017867
BDB017867
|
US10544132, Example 26
CC1(CO[C@]2(c3ccc(Cl)cc3)c3ccc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cc2)COC1
|
C29H29Cl2NO4 526.460000 |
JPJMGSQFTCZFQV-GDLZYMKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427072; PubChem:CID135281408
|
Local ready
Direct docking supported
|
|
E3L017868
BDB017868
|
US10544132, Example 27
C[C@](O)(CO)c1ccc2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@]2(C)OCC1(CO)CC1
|
C25H28N2O5 436.508000 |
RGPOYMGRXRWDFL-BJKOFHAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427073; PubChem:CID154732956
|
Local ready
Direct docking supported
|
|
E3L017869
BDB017869
|
US10544132, Example 28
CC(O)(CO)c1ccc2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@]2(C)OCC1(CO)CC1
|
C25H28N2O5 436.508000 |
RGPOYMGRXRWDFL-XMMISQBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427074; PubChem:CID145765548
|
Local ready
Direct docking supported
|
|
E3L017870
BDB017870
|
US10544132, Example 29
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(O)CC1)c1ccc(Cl)cc1
|
C28H27Cl2NO4 512.433000 |
RCIVCEHJWTYZDO-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427075; PubChem:CID135281489
|
Local ready
Direct docking supported
|
|
E3L017871
BDB017871
|
US10544132, Example 30
CN(C)C(=O)CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cc1
|
C28H28Cl2N2O4 527.448000 |
RRQCJUUJERJVBP-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427076; PubChem:CID135281547
|
Local ready
Direct docking supported
|
|
E3L017872
BDB017872
|
US10544132, Example 31
COCC1(CO[C@]2(c3ccc(Cl)cc3)c3ccc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cc2)CC1
|
C30H31Cl2NO4 540.487000 |
RARQEPSEJKMFPX-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427077; PubChem:CID135281414
|
Local ready
Direct docking supported
|
|
E3L017873
BDB017873
|
US10544132, Example 33
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1C(=O)O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H29Cl2NO6 570.469000 |
NQWVLAWWWVVUAN-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427078; PubChem:CID135281410
|
Local ready
Direct docking supported
|
|
E3L017874
BDB017874
|
US10544132, Example 34
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(=O)(=O)N1CCOCC1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C33H36Cl2N2O7S 675.631000 |
JFAQMYZAZWRRKT-MGBGTMOVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427079; PubChem:CID135281697
|
Local ready
Direct docking supported
|
|
E3L017875
BDB017875
|
US10544132, Example 35
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)C2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1
|
C30H29Cl2FN2O6S 635.541000 |
QXTIAAQSOXPAAN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427080; PubChem:CID154732957
|
Local ready
Direct docking supported
|
|
E3L017876
BDB017876
|
US10544132, Example 36
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H31Cl2NO6S 604.552000 |
RXUWUIRMPWZSAR-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427081; PubChem:CID154732958
|
Local ready
Direct docking supported
|
|
E3L017877
BDB017877
|
US10544132, Example 37
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(O[C@@H]1CCOC1)c1ccc(Cl)cc1
|
C28H27Cl2NO4 512.433000 |
ITVICYXWRBVNRA-QDPGVEIFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427082; PubChem:CID154732959
|
Local ready
Direct docking supported
|
|
E3L017878
BDB017878
|
US10544132, Example 38
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C28H27Cl2NO4 512.433000 |
ITVICYXWRBVNRA-NEKDWFFYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427083; PubChem:CID154732960
|
Local ready
Direct docking supported
|
|
E3L017879
BDB017879
|
US10544132, Example 39
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC[C@H]1CCOC1)c1ccc(Cl)cc1
|
C29H29Cl2NO4 526.460000 |
OTIYWWDOPCSJHZ-AFJIDDCJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427084; PubChem:CID154732961
|
Local ready
Direct docking supported
|
|
E3L017880
BDB017880
|
US10544132, Example 40
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC[C@@H]1CCOC1)c1ccc(Cl)cc1
|
C29H29Cl2NO4 526.460000 |
OTIYWWDOPCSJHZ-ACSYHNTCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427085; PubChem:CID154732962
|
Local ready
Direct docking supported
|