| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L017901
BDB017901
|
US10544132, Example 63
COC[C@@](C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H32Cl2FNO7S 652.568000 |
XPPOSVDBYKUPEU-BVRKHOPBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427116; PubChem:CID154732975
|
Local ready
Direct docking supported
|
|
E3L017902
BDB017902
|
US10544132, Example 64
COC[C@](C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H32Cl2FNO7S 652.568000 |
XPPOSVDBYKUPEU-IGYGKHONSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427117; PubChem:CID154732976
|
Local ready
Direct docking supported
|
|
E3L017903
BDB017903
|
US10544132, Example 65
C[C@@](O)(CO)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO7S 638.541000 |
HJVLHGXGDKFDKJ-PQHLKRTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427118; PubChem:CID154732977
|
Local ready
Direct docking supported
|
|
E3L017904
BDB017904
|
US10544132, Example 66
C[C@](O)(CO)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO7S 638.541000 |
HJVLHGXGDKFDKJ-MFMCTBQISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427119; PubChem:CID154732978
|
Local ready
Direct docking supported
|
|
E3L017905
BDB017905
|
US10544132, Example 67
CN1CCN(C[C@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(O[C@@H]2CCOC2)c2ccc(Cl)cc2)CC1
|
C34H38Cl2FN3O6S 706.664000 |
GEZPZMXREXHEJZ-LKDIDBIPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427120; PubChem:CID154732979
|
Local ready
Direct docking supported
|
|
E3L017906
BDB017906
|
US10544132, Example 68
CN1CCN(C[C@@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(O[C@@H]2CCOC2)c2ccc(Cl)cc2)CC1
|
C34H38Cl2FN3O6S 706.664000 |
GEZPZMXREXHEJZ-WTWHSOPRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427121; PubChem:CID154732980
|
Local ready
Direct docking supported
|
|
E3L017907
BDB017907
|
US10544132, Example 69
CN1CCN(C[C@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(O[C@H]2CCOC2)c2ccc(Cl)cc2)CC1
|
C34H38Cl2FN3O6S 706.664000 |
GEZPZMXREXHEJZ-FBBJSWSOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427122; PubChem:CID154732981
|
Local ready
Direct docking supported
|
|
E3L017908
BDB017908
|
US10544132, Example 70
CN1CCN(C[C@@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(O[C@H]2CCOC2)c2ccc(Cl)cc2)CC1
|
C34H38Cl2FN3O6S 706.664000 |
GEZPZMXREXHEJZ-HOMOBGQPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427123; PubChem:CID154732982
|
Local ready
Direct docking supported
|
|
E3L017909
BDB017909
|
US10544132, Example 71
CC(C)(O)c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C30H28Cl2FNO6 588.459000 |
PMXGSEVMEXTCLI-SGOMLOLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427124; PubChem:CID135281459
|
Local ready
Direct docking supported
|
|
E3L017910
BDB017910
|
US10544132, Example 72
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1CO)[C@@]2(OCC1(C#N)CC1)c1ccc(Cl)cc1
|
C30H27Cl2FN2O4 569.460000 |
FZOWPLQXTSEWMX-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427125; PubChem:CID135281421
|
Local ready
Direct docking supported
|
|
E3L017911
BDB017911
|
US10544132, Example 73
Cn1cc([C@@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(C(N)=O)CC2)c2ccc(Cl)cc2)cn1
|
C33H31Cl2FN4O6S 701.604000 |
YLXVSCUQMYZKFT-CQTOTRCISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427126; PubChem:CID154732983
|
Local ready
Direct docking supported
|
|
E3L017912
BDB017912
|
US10544132, Example 74
Cn1cc([C@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(C(N)=O)CC2)c2ccc(Cl)cc2)cn1
|
C33H31Cl2FN4O6S 701.604000 |
YLXVSCUQMYZKFT-ZQWAWDFXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427127; PubChem:CID154732984
|
Local ready
Direct docking supported
|
|
E3L017913
BDB017913
|
US10544132, Example 75
Cn1cc([C@@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(O)CC2)c2ccc(Cl)cc2)cn1
|
C32H30Cl2FN3O6S 674.578000 |
FATKFLNSLQQUOY-XDFJSJKPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427128; PubChem:CID145765602
|
Local ready
Direct docking supported
|
|
E3L017914
BDB017914
|
US10544132, Example 76
Cn1cc([C@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(O)CC2)c2ccc(Cl)cc2)cn1
|
C32H30Cl2FN3O6S 674.578000 |
FATKFLNSLQQUOY-XLJNKUFUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427129; PubChem:CID145765612
|
Local ready
Direct docking supported
|
|
E3L017915
BDB017915
|
US10544132, Example 77
CN1CCN(C[C@@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C35H40Cl2FN3O6S 720.691000 |
UAASDXMLTUDYGD-VLZNPVHKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427130; PubChem:CID154732985
|
Local ready
Direct docking supported
|
|
E3L017916
BDB017916
|
US10544132, Example 78
CN1CCN(C[C@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C35H40Cl2FN3O6S 720.691000 |
UAASDXMLTUDYGD-QWOOXDRHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427131; PubChem:CID154732986
|
Local ready
Direct docking supported
|
|
E3L017917
BDB017917
|
US10544132, Example 79
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1C(=O)O)[C@@]2(OCC1(C#N)CC1)c1ccc(Cl)cc1
|
C30H25Cl2FN2O5 583.443000 |
DEAVUDZEMMDBRA-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427132; PubChem:CID135281403
|
Local ready
Direct docking supported
|
|
E3L017918
BDB017918
|
US10544132, Example 80
CN1CCC([C@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C35H39Cl2FN2O6S 705.676000 |
MNUHQOFWGYDTKI-QWOOXDRHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427133; PubChem:CID154732987
|
Local ready
Direct docking supported
|
|
E3L017919
BDB017919
|
US10544132, Example 81
CN1CCC([C@@](C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C35H39Cl2FN2O6S 705.676000 |
MNUHQOFWGYDTKI-VLZNPVHKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427134; PubChem:CID154732988
|
Local ready
Direct docking supported
|
|
E3L017920
BDB017920
|
US10544132, Example 82
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1P(C)(C)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H33Cl2FNO5P 620.485000 |
IARKWVZHJYWTDX-WJOKGBTCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427135; PubChem:CID137405337
|
Local ready
Direct docking supported
|