| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L017921
BDB017921
|
US10544132, Example 83
CS(=O)(=O)c1cc(Cl)ccc1CN1C(=O)c2cc([C@@H](O)C3CCOCC3)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C33H34Cl2FNO7S 678.606000 |
IRIZYNABKNVLML-BZKUTMRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427136; PubChem:CID154732989
|
Local ready
Direct docking supported
|
|
E3L017922
BDB017922
|
US10544132, Example 84
CS(=O)(=O)c1cc(Cl)ccc1CN1C(=O)c2cc([C@H](O)C3CCOCC3)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C33H34Cl2FNO7S 678.606000 |
IRIZYNABKNVLML-LXANVCGNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427139; PubChem:CID154732991
|
Local ready
Direct docking supported
|
|
E3L017923
BDB017923
|
US10544132, Example 85
C[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C34H35Cl2FN2O7S 705.632000 |
WPEIHYLRRFWOGP-ZFEZZJPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427143; PubChem:CID154732993
|
Local ready
Direct docking supported
|
|
E3L017924
BDB017924
|
US10544132, Example 86
C[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C34H35Cl2FN2O7S 705.632000 |
WPEIHYLRRFWOGP-UZNNEEJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427145; PubChem:CID154732994
|
Local ready
Direct docking supported
|
|
E3L017925
BDB017925
|
US10544132, Example 87
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)C3CCN(C)CC3)cc2C(=O)N1Cc1ccc(Cl)cc1C(=O)O
|
C31H31Cl2FN2O5 601.502000 |
PGUDRRCAMVOBPY-NLIBRCFJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427146; PubChem:CID135281456
|
Local ready
Direct docking supported
|
|
E3L017926
BDB017926
|
US10544132, Example 88
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@@](C)(O)C3CCOCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C31H30Cl2FNO6 602.486000 |
AVDHVIXZENQIRS-HOSFBAFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427147; PubChem:CID154732995
|
Local ready
Direct docking supported
|
|
E3L017927
BDB017927
|
US10544132, Example 89
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@](C)(O)C3CCOCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C31H30Cl2FNO6 602.486000 |
AVDHVIXZENQIRS-MAJWKWKESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427148; PubChem:CID154732996
|
Local ready
Direct docking supported
|
|
E3L017928
BDB017928
|
US10544132, Example 90
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CO)c1ccc(C#N)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O5 631.104000 |
DLDOXTZEZBHSKM-PRLHHBRKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427149; PubChem:CID154732997
|
Local ready
Direct docking supported
|
|
E3L017929
BDB017929
|
US10544132, Example 91
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CO)c1ccc(C#N)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O5 631.104000 |
DLDOXTZEZBHSKM-ZZQNMKAFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427150; PubChem:CID154732998
|
Local ready
Direct docking supported
|
|
E3L017930
BDB017930
|
US10544132, Example 92
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1CO)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O5 631.104000 |
LQLKHTDURGSYEY-FBBJSWSOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427152; PubChem:CID154732999
|
Local ready
Direct docking supported
|
|
E3L017931
BDB017931
|
US10544132, Example 93
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1CO)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O5 631.104000 |
LQLKHTDURGSYEY-HOMOBGQPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427153; PubChem:CID154733000
|
Local ready
Direct docking supported
|
|
E3L017932
BDB017932
|
US10544132, Example 94
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O4 615.105000 |
ZOWAIYZZMIRJLG-SZAHLOSFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427154; PubChem:CID154733001
|
Local ready
Direct docking supported
|
|
E3L017933
BDB017933
|
US10544132, Example 95
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O4 615.105000 |
ZOWAIYZZMIRJLG-KKLWWLSJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427155; PubChem:CID154733002
|
Local ready
Direct docking supported
|
|
E3L017934
BDB017934
|
US10544132, Example 96
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C33H30ClFN4O4 601.078000 |
CDUKUNZREUVQKN-FRJUPVQCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427156; PubChem:CID154733003
|
Local ready
Direct docking supported
|
|
E3L017935
BDB017935
|
US10544132, Example 97
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C33H30ClFN4O4 601.078000 |
CDUKUNZREUVQKN-WNNZTAQKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427157; PubChem:CID154733004
|
Local ready
Direct docking supported
|
|
E3L017936
BDB017936
|
US10544132, Example 98
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@](C)(O)C3(F)CCOCC3)cc2C(=O)N1[C@H](CC(=O)O)c1ccc(Cl)cc1
|
C31H29Cl2F2NO6 620.476000 |
HZTQINJSGAPBLS-JEVIFJNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427158; PubChem:CID154733005
|
Local ready
Direct docking supported
|
|
E3L017937
BDB017937
|
US10544132, Example 99
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@@](C)(O)C3(F)CCOCC3)cc2C(=O)N1[C@H](CC(=O)O)c1ccc(Cl)cc1
|
C31H29Cl2F2NO6 620.476000 |
HZTQINJSGAPBLS-DSXODZLMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427159; PubChem:CID154733006
|
Local ready
Direct docking supported
|
|
E3L017938
BDB017938
|
US10544132, Example 100
CCC(O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CCC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)c1ccn(C)n1
|
C32H30Cl2FN3O5 626.512000 |
ACCSRYKZIIOHIZ-LTZUXFEUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427160; PubChem:CID135281496
|
Local ready
Direct docking supported
|
|
E3L017939
BDB017939
|
US10544132, Example 101
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C32H31Cl2F2NO6 634.503000 |
HXHSKGLWTNIZIS-XBZWSRNISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427161; PubChem:CID154733007
|
Local ready
Direct docking supported
|
|
E3L017940
BDB017940
|
US10544132, Example 102
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C32H31Cl2F2NO6 634.503000 |
HXHSKGLWTNIZIS-OODHRNECSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427162; PubChem:CID154733008
|
Local ready
Direct docking supported
|