| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L017881
BDB017881
|
US10544132, Example 41
C[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C34H36Cl2FNO7S 692.633000 |
JFGISRYCIHBUCK-ZFEZZJPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427086; PubChem:CID154732963
|
Local ready
Direct docking supported
|
|
E3L017882
BDB017882
|
US10544132, Example 42
C[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C34H36Cl2FNO7S 692.633000 |
JFGISRYCIHBUCK-UZNNEEJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427087; PubChem:CID154732964
|
Local ready
Direct docking supported
|
|
E3L017883
BDB017883
|
US10544132, Example 43
C[C@@](O)(CN1CCNCC1)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C34H38Cl2FN3O6S 706.664000 |
NTYHQRPYZXGTGT-ZFEZZJPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427088; PubChem:CID154732965
|
Local ready
Direct docking supported
|
|
E3L017884
BDB017884
|
US10544132, Example 44
C[C@](O)(CN1CCNCC1)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C34H38Cl2FN3O6S 706.664000 |
NTYHQRPYZXGTGT-UZNNEEJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427089; PubChem:CID154732966
|
Local ready
Direct docking supported
|
|
E3L017885
BDB017885
|
US10544132, Example 45
C[C@@H](c1ccc(Cl)cc1)N1C(=O)c2cc(C(C)(C)O)ccc2[C@]1(OC1COC[C@H]1O)c1ccc(Cl)cc1
|
C29H29Cl2NO5 542.459000 |
JLJRDOGQKDSPHW-BKVJDPFESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427090; PubChem:CID145765588
|
Local ready
Direct docking supported
|
|
E3L017886
BDB017886
|
US10544132, Example 46
C[C@@H](c1ccc(Cl)cc1)N1C(=O)c2cc(C(C)(C)O)ccc2[C@]1(OC1COC[C@@H]1O)c1ccc(Cl)cc1
|
C29H29Cl2NO5 542.459000 |
JLJRDOGQKDSPHW-QYEDSFCJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427091; PubChem:CID154732967
|
Local ready
Direct docking supported
|
|
E3L017887
BDB017887
|
US10544132, Example 47
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cc1
|
C25H23Cl2NO3 456.369000 |
GBBKEWOTKMXEJW-RUZDIDTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427092; PubChem:CID135281412
|
Local ready
Direct docking supported
|
|
E3L017888
BDB017888
|
US10544132, Example 49
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCCCO)c1ccc(Cl)cc1
|
C27H27Cl2NO4 500.422000 |
OAZOTQYKBROZDC-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427095; PubChem:CID135281478
|
Local ready
Direct docking supported
|
|
E3L017889
BDB017889
|
US10544132, Example 50
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO6S 622.542000 |
UZPANWLGEIIIFW-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427098; PubChem:CID135281647
|
Local ready
Direct docking supported
|
|
E3L017890
BDB017890
|
US10544132, Example 51
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC(F)(F)CO)c1ccc(Cl)cc1
|
C27H25Cl2F2NO4 536.402000 |
DKLIPENWHNVPEY-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427099; PubChem:CID135281507
|
Local ready
Direct docking supported
|
|
E3L017891
BDB017891
|
US10544132, Example 52
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC[C@H]1CC[C@H]1CO)c1ccc(Cl)cc1
|
C30H31Cl2NO4 540.487000 |
YJPCYIKTKXDGAX-KSWJDTNCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427101; PubChem:CID137411534
|
Local ready
Direct docking supported
|
|
E3L017892
BDB017892
|
US10544132, Example 53
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC[C@H]1CC[C@@H]1CO)c1ccc(Cl)cc1
|
C30H31Cl2NO4 540.487000 |
YJPCYIKTKXDGAX-URCPOSBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427102; PubChem:CID154732968
|
Local ready
Direct docking supported
|
|
E3L017893
BDB017893
|
US10544132, Example 54
CC(O)(C(=O)N1CCCC1)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C33H34Cl2N2O5 609.550000 |
AVCINXLMIYQZIG-NFCCVXSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427103; PubChem:CID135281508
|
Local ready
Direct docking supported
|
|
E3L017894
BDB017894
|
US10544132, Example 56
CN(C)C(=O)[C@@](C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H32Cl2N2O5 583.512000 |
QSQWTXWPCPYZCQ-IGYGKHONSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427104; PubChem:CID154732969
|
Local ready
Direct docking supported
|
|
E3L017895
BDB017895
|
US10544132, Example 57
CN(C)C(=O)[C@](C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H32Cl2N2O5 583.512000 |
QSQWTXWPCPYZCQ-BVRKHOPBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427108; PubChem:CID154732970
|
Local ready
Direct docking supported
|
|
E3L017896
BDB017896
|
US10544132, Example 58
CNC(=O)[C@@](C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2N2O5 569.485000 |
FLAAYSHQWIAMDD-MFMCTBQISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427109; PubChem:CID154732971
|
Local ready
Direct docking supported
|
|
E3L017897
BDB017897
|
US10544132, Example 59
CNC(=O)[C@](C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2N2O5 569.485000 |
FLAAYSHQWIAMDD-PQHLKRTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427110; PubChem:CID154732972
|
Local ready
Direct docking supported
|
|
E3L017898
BDB017898
|
US10544132, Example 60
CSc1cc(Cl)ccc1CN1C(=O)c2cc(C(C)(C)O)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO4S 590.544000 |
OAWFYJRYUZCBKK-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427111; PubChem:CID135281694
|
Local ready
Direct docking supported
|
|
E3L017899
BDB017899
|
US10544132, Example 61
C[S@+]([O-])c1cc(Cl)ccc1CN1C(=O)c2cc(C(C)(C)O)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO5S 606.543000 |
PVRYETGYPNIACM-FRRBMJAGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427113; PubChem:CID154732973
|
Local ready
Direct docking supported
|
|
E3L017900
BDB017900
|
US10544132, Example 62
C[S@@+]([O-])c1cc(Cl)ccc1CN1C(=O)c2cc(C(C)(C)O)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO5S 606.543000 |
PVRYETGYPNIACM-HFOCTHEHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427115; PubChem:CID154732974
|
Local ready
Direct docking supported
|