| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L017941
BDB017941
|
US10544132, Example 103
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@](C)(O)C3CCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C30H28Cl2FNO5 572.460000 |
BVCCIEZECAVANS-AWJLRTIGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427163; PubChem:CID154733009
|
Local ready
Direct docking supported
|
|
E3L017942
BDB017942
|
US10544132, Example 104
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@@](C)(O)C3CCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C30H28Cl2FNO5 572.460000 |
BVCCIEZECAVANS-JPHFWNGBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427164; PubChem:CID154733010
|
Local ready
Direct docking supported
|
|
E3L017943
BDB017943
|
US10544132, Example 105
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C32H32Cl2FNO6 616.513000 |
TXTARTLLGHDDSD-RKVVATLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427165; PubChem:CID154733011
|
Local ready
Direct docking supported
|
|
E3L017944
BDB017944
|
US10544132, Example 106
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C32H32Cl2FNO6 616.513000 |
TXTARTLLGHDDSD-QUBLIXHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427166; PubChem:CID135281471
|
Local ready
Direct docking supported
|
|
E3L017945
BDB017945
|
US10544132, Example 107
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CCC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C33H34Cl2FNO6 630.540000 |
YDGNPXHTWKENIC-KXLBIAJQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427167; PubChem:CID135281641
|
Local ready
Direct docking supported
|
|
E3L017946
BDB017946
|
US10544132, Example 108
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CCC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C33H34Cl2FNO6 630.540000 |
YDGNPXHTWKENIC-XEUSQTKLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427168; PubChem:CID135281545
|
Local ready
Direct docking supported
|
|
E3L017947
BDB017947
|
BDBM427169
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CCC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C33H33Cl2F2NO6 648.530000 |
KQTPBMJSGVVRKO-SKTNCWGXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427169; PubChem:CID135281499
|
Local ready
Direct docking supported
|
|
E3L017948
BDB017948
|
US10544132, Example 111
CCO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@](O)(CC)C3(F)CCOCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C33H33Cl2F2NO6 648.530000 |
JMXJOWWAIDYRLU-SKTNCWGXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427171; PubChem:CID135281526
|
Local ready
Direct docking supported
|
|
E3L017949
BDB017949
|
US10544132, Example 113
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CCC(=O)O)c1ccc(OC)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C34H36ClF2NO7 644.111000 |
NOKLTVPSPDXSBE-HUTUBIKLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427172; PubChem:CID135281626
|
Local ready
Direct docking supported
|
|
E3L017950
BDB017950
|
BDBM427173
CCC(O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CCC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
|
C34H36Cl2FNO6 644.567000 |
QJTCYWYDSIOJFY-OYLRFEPJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM427173
|
Local ready
Direct docking supported
|
|
E3L017951
BDB017951
|
BDBM427174
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1OCC(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C32H31Cl2F2NO7 650.502000 |
JJZSDEJWGNDCRG-ROJLCIKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427174; PubChem:CID145283258
|
Local ready
Direct docking supported
|
|
E3L017952
BDB017952
|
US10544132, Example 116
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C31H30Cl2FNO6 602.486000 |
NOIABBKIABICFM-IOWSJCHKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427175; PubChem:CID135281393
|
Local ready
Direct docking supported
|
|
E3L017953
BDB017953
|
US10544132, Example 117
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C31H30Cl2FNO6 602.486000 |
NOIABBKIABICFM-FIRIVFDPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427176; PubChem:CID135281388
|
Local ready
Direct docking supported
|
|
E3L017954
BDB017954
|
US10544132, Example 118
CCO[C@]1(c2ccc(Cl)cc2)c2c(F)cc([C@](O)(CC)C3CCOCC3)cc2C(=O)N1Cc1ccc(Cl)cc1C(=O)O
|
C32H32Cl2FNO6 616.513000 |
DLUFTCNJNCOQGS-AJQTZOPKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427177; PubChem:CID135281631
|
Local ready
Direct docking supported
|
|
E3L017955
BDB017955
|
US10544132, Example 119
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C)cc1C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C32H32ClF2NO6 600.058000 |
XFQWQHWLXCPJND-ROJLCIKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427178; PubChem:CID135281401
|
Local ready
Direct docking supported
|
|
E3L017956
BDB017956
|
BDBM427179
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(OC)cc1C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C32H32ClF2NO7 616.057000 |
AMRXPNINJISJEN-ROJLCIKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427179; PubChem:CID135281709
|
Local ready
Direct docking supported
|
|
E3L017957
BDB017957
|
BDBM427180
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1C(C)(C)C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C34H36Cl2FNO6 644.567000 |
DMHHJJRAOBKLND-SZAHLOSFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427180; PubChem:CID135281424
|
Local ready
Direct docking supported
|
|
E3L017958
BDB017958
|
BDBM427181
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1CC(=O)O)C2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C32H32Cl2FNO6 616.513000 |
KSQHEVCOEVTEOI-CYZZXXEPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427181; PubChem:CID154733013
|
Local ready
Direct docking supported
|
|
E3L017959
BDB017959
|
US10544132, Example 123
CC[C@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1CC(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C32H32Cl2FNO6 616.513000 |
KSQHEVCOEVTEOI-ROJLCIKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427182; PubChem:CID135281591
|
Local ready
Direct docking supported
|
|
E3L017960
BDB017960
|
BDBM427183
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N([C@H](c1ccc(Cl)cc1)[C@H](C)C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1CCOCC1
|
C33H34Cl2FNO6 630.540000 |
JDCHPEZNOKLHPK-KJEAJVGRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM427183; PubChem:CID135281467
|
Local ready
Direct docking supported
|