| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L018061
BDB018061
|
US10576064, Example I-270
CNC(=O)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C32H29Cl2FN4O3 607.513000 |
LXZQARWOAZGMFD-ACIRYHQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432035; PubChem:CID118641429
|
Local ready
Direct docking supported
|
|
E3L018062
BDB018062
|
US10576064, Example I-272
CN(C)C(=O)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C33H31Cl2FN4O3 621.540000 |
ZDXPUWCVIHQHFW-UUZIFAJNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432036; PubChem:CID118636561
|
Local ready
Direct docking supported
|
|
E3L018063
BDB018063
|
US10576064, Example I-274
O=C(NO)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C31H27Cl2FN4O4 609.485000 |
QMVBUNXZEIOLHH-GURVGDRESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432037; PubChem:CID118641433
|
Local ready
Direct docking supported
|
|
E3L018064
BDB018064
|
US10576064, Example I-276
CN(O)C(=O)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C32H29Cl2FN4O4 623.512000 |
UALMRMQALCBXLK-ACIRYHQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432038; PubChem:CID118636562
|
Local ready
Direct docking supported
|
|
E3L018065
BDB018065
|
US10576064, Example I-278
CON(C)C(=O)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C33H31Cl2FN4O4 637.539000 |
GMIATVSRFQVTEO-UUZIFAJNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432039; PubChem:CID118636563
|
Local ready
Direct docking supported
|
|
E3L018066
BDB018066
|
US10576064, Example I-280
NC(=O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C30H25Cl2FN4O3 579.459000 |
XJNDMKUTROFFHA-YDXRHMNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432040; PubChem:CID118636565
|
Local ready
Direct docking supported
|
|
E3L018067
BDB018067
|
US10576064, Example I-281
NC(=O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1C(F)(F)F
|
C31H24Cl2F4N4O3 647.456000 |
SVNZEINXFXYQOT-YDXRHMNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432041; PubChem:CID118636564
|
Local ready
Direct docking supported
|
|
E3L018068
BDB018068
|
US10576064, Example I-283
CCOc1cccc(CN2[C@H]3CN(c4ccc(C(=O)NO)cc4)C(=O)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
|
C35H29Cl2FN4O5 675.544000 |
TXEOBRAQWREDST-VLWKUZPGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432042; PubChem:CID118641483
|
Local ready
Direct docking supported
|
|
E3L018069
BDB018069
|
US10576064, Example I-284
CCOc1cccc(CN2[C@H]3CN(c4ccc(C(N)=O)cc4)C(=O)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
|
C35H29Cl2FN4O4 659.545000 |
ZZGZPGFLJIUMOA-VLWKUZPGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432043; PubChem:CID118636566
|
Local ready
Direct docking supported
|
|
E3L018070
BDB018070
|
US10576064, Example I-285
O=C(NO)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C30H25Cl2FN4O4 595.458000 |
IBTJEANAVUETOB-YDXRHMNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432044; PubChem:CID118641835
|
Local ready
Direct docking supported
|
|
E3L018071
BDB018071
|
US10576064, Example I-286
CN(C)C(=O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C32H29Cl2FN4O3 607.513000 |
MTTDHHBLCNBSHM-ACIRYHQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432045; PubChem:CID118636568
|
Local ready
Direct docking supported
|
|
E3L018072
BDB018072
|
US10576064, Example I-287
CNC(=O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C31H27Cl2FN4O3 593.486000 |
QNCYRMZLSMSOFL-GURVGDRESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432046; PubChem:CID118636567
|
Local ready
Direct docking supported
|
|
E3L018073
BDB018073
|
US10576064, Example I-288
NC(=O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2ccnc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C29H24Cl2FN5O3 580.447000 |
BJZXIXJLALJMFM-LQZKXZFMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432047; PubChem:CID118636569
|
Local ready
Direct docking supported
|
|
E3L018074
BDB018074
|
US10576064, Example I-290
O=C(O)c1ccc(-c2cc(Cl)c(F)c([C@H]3[C@@H]4C(=O)NCC[C@@H]4N(CC4CC4)[C@@]34C(=O)Nc3cc(Cl)ccc34)c2)cc1
|
C31H26Cl2FN3O4 594.470000 |
KACHZTMRZFNBSZ-GURVGDRESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432048; PubChem:CID118639850
|
Local ready
Direct docking supported
|
|
E3L018075
BDB018075
|
US10576064, Example I-292
Nc1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C30H27Cl2FN4O2 565.476000 |
ZARWVZYKRKCTBJ-YRIIQKNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432049; PubChem:CID118636570
|
Local ready
Direct docking supported
|
|
E3L018076
BDB018076
|
US10576064, Example I-296
CC(=O)Nc1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C32H29Cl2FN4O3 607.513000 |
YHORSGKMLICEHG-CKXMCULTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432050; PubChem:CID118636572
|
Local ready
Direct docking supported
|
|
E3L018077
BDB018077
|
US10576064, Example I-298
O=CNc1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C31H27Cl2FN4O3 593.486000 |
VYWZDCOPSOGJLL-OVDFTCDZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432051; PubChem:CID118636574
|
Local ready
Direct docking supported
|
|
E3L018078
BDB018078
|
US10576064, Example I-300
CS(=O)(=O)Nc1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C31H29Cl2FN4O4S 643.568000 |
ZNNPWQWETDZFFW-OVDFTCDZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432052; PubChem:CID118636575
|
Local ready
Direct docking supported
|
|
E3L018079
BDB018079
|
US10576064, Example I-302
CS(=O)(=O)Nc1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1F
|
C30H26Cl2F2N4O4S 647.531000 |
STILUIOVWZGPAV-YRIIQKNPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432053; PubChem:CID118641434
|
Local ready
Direct docking supported
|
|
E3L018080
BDB018080
|
US10576064, Example I-304
CCOC(=O)CNc1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C34H33Cl2FN4O4 651.566000 |
OLOSVHAXPRQGKJ-AKMMMNCQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432054; PubChem:CID118636576
|
Local ready
Direct docking supported
|