| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L018021
BDB018021
|
US10576064, Example I-198
O=C(O)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CCC2)cc1
|
C32H28Cl2FN3O4 608.497000 |
NDXNEQUBTZHDFA-ACIRYHQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431992; PubChem:CID118636521
|
Local ready
Direct docking supported
|
|
E3L018022
BDB018022
|
US10576064, Example I-200
COc1cc(C(=O)O)ccc1N1CC[C@H]2[C@@H](C1=O)[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CCC1
|
C33H30Cl2FN3O5 638.523000 |
ZUKLNSFUDLMAOA-JLLCTVPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431993; PubChem:CID118636522
|
Local ready
Direct docking supported
|
|
E3L018023
BDB018023
|
US10576064, Example I-202
CC(C)(C)CN1[C@H]2CCN(c3ccc(C(=O)O)cc3)C(=O)[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C32H30Cl2FN3O4 610.513000 |
YJLOBQOXVWOPPZ-ZVJSOJQNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431994; PubChem:CID118636523
|
Local ready
Direct docking supported
|
|
E3L018024
BDB018024
|
US10576064, Example I-204
O=C(O)c1ccc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Br)ccc42)N3CC2CC2)cc1
|
C31H26BrClFN3O4 638.921000 |
QRWQVQIPVROZIK-GURVGDRESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431995; PubChem:CID118636524
|
Local ready
Direct docking supported
|
|
E3L018025
BDB018025
|
US10576064, Example I-206
Cc1cc(N2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc(C)c1C(=O)O
|
C33H30Cl2FN3O4 622.524000 |
OSYXIHMFGARYQG-JLLCTVPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431996; PubChem:CID118636525
|
Local ready
Direct docking supported
|
|
E3L018026
BDB018026
|
US10576064, Example I-208
O=C(O)c1ccc(CN2CC[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C32H28Cl2FN3O4 608.497000 |
VWLYRWRTDYSBJB-ACIRYHQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431997; PubChem:CID118636526
|
Local ready
Direct docking supported
|
|
E3L018027
BDB018027
|
US10576064, Example I-210
CC(C)(C)CN1[C@H]2CCN(Cc3ccc(C(=O)O)cc3)C(=O)[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C33H32Cl2FN3O4 624.540000 |
YQXVFLWEXVPGOC-LIHQSLCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431998; PubChem:CID118636527
|
Local ready
Direct docking supported
|
|
E3L018028
BDB018028
|
US10576064, Example I-212
CCOc1cccc(CN2[C@H]3CCN(Cc4ccc(C(=O)O)cc4)C(=O)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
|
C37H32Cl2FN3O5 688.583000 |
UCGWFKIGVYYLIJ-AWYYSMRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM431999; PubChem:CID118636528
|
Local ready
Direct docking supported
|
|
E3L018029
BDB018029
|
US10576064, Example I-214
COc1cccc(CN2[C@H]3CCN(Cc4ccc(C(=O)O)cc4)C(=O)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]23C(=O)Nc2cc(Cl)ccc23)c1
|
C36H30Cl2FN3O5 674.556000 |
VJWXXSSEHVXWTP-GHFJTSGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432000; PubChem:CID118636529
|
Local ready
Direct docking supported
|
|
E3L018030
BDB018030
|
US10576064, Example I-216
O=C(O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C30H24Cl2FN3O4 580.443000 |
VBSBZEWOGJQBHV-YDXRHMNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432001; PubChem:CID118636530
|
Local ready
Direct docking supported
|
|
E3L018031
BDB018031
|
US10576064, Example I-218
O=C(O)c1ccc(N2C[C@@H]3[C@H](C2=O)[C@@H](c2cccc(Cl)c2F)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C30H24Cl2FN3O4 580.443000 |
VBSBZEWOGJQBHV-ZXPXOXBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432003; PubChem:CID118636489
|
Local ready
Direct docking supported
|
|
E3L018032
BDB018032
|
US10576064, Example I-219
COc1cc(C(=O)O)ccc1N1C[C@H]2[C@@H](C1=O)[C@H](c1cccc(Cl)c1F)[C@]1(C(=O)Nc3cc(Cl)ccc31)N2CC1CC1
|
C31H26Cl2FN3O5 610.469000 |
LZOUDXJTKFIDHB-BQNOKLPLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432004; PubChem:CID118636531
|
Local ready
Direct docking supported
|
|
E3L018033
BDB018033
|
US10576064, Example I-221
O=C(O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CCC2)cc1
|
C31H26Cl2FN3O4 594.470000 |
ZZBLQOXLGBBFOV-GURVGDRESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432005; PubChem:CID118636532
|
Local ready
Direct docking supported
|
|
E3L018034
BDB018034
|
US10576064, Example I-223
O=C(O)c1ccc(N2C[C@@H]3[C@H](C2=O)[C@@H](c2cccc(Cl)c2F)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CCC2)cc1
|
C31H26Cl2FN3O4 594.470000 |
ZZBLQOXLGBBFOV-ANKKVJNISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432006; PubChem:CID118636535
|
Local ready
Direct docking supported
|
|
E3L018035
BDB018035
|
US10576064, Example I-224
COCCN1[C@H]2CN(c3ccc(C(=O)O)cc3)C(=O)[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C29H24Cl2FN3O5 584.431000 |
JVSQJENQMMPUMK-HNFJUSDZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432007; PubChem:CID118636533
|
Local ready
Direct docking supported
|
|
E3L018036
BDB018036
|
US10576064, Example I-226
O=C(O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CCC(F)(F)F)cc1
|
C29H21Cl2F4N3O4 622.402000 |
GVNUTUCQUFMITC-LQZKXZFMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432008; PubChem:CID118636534
|
Local ready
Direct docking supported
|
|
E3L018037
BDB018037
|
US10576064, Example I-228
CC(C)(C)CN1[C@H]2CN(c3ccc(C(=O)O)cc3)C(=O)[C@H]2[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C31H28Cl2FN3O4 596.486000 |
QSFUOMOVHNPERZ-TXHDDHBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432009; PubChem:CID118636536
|
Local ready
Direct docking supported
|
|
E3L018038
BDB018038
|
US10576064, Example I-230
O=C(O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC(F)(F)C2)cc1
|
C31H24Cl2F3N3O4 630.450000 |
KQHCBDNGTQZFFX-TXHDDHBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432011; PubChem:CID118636537
|
Local ready
Direct docking supported
|
|
E3L018039
BDB018039
|
US10576064, Example I-231
O=C(O)C(=O)c1ccc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)cc1
|
C31H24Cl2FN3O5 608.453000 |
IQCYUNAJDGBXQO-TXHDDHBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432012; PubChem:CID118636538
|
Local ready
Direct docking supported
|
|
E3L018040
BDB018040
|
US10576064, Example I-233
O=C(O)c1csc(N2C[C@H]3[C@@H](C2=O)[C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc4cc(Cl)ccc42)N3CC2CC2)n1
|
C27H21Cl2FN4O4S 587.460000 |
RJGCAARZUCDBMF-ZZWZOVRCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM432013; PubChem:CID118636539
|
Local ready
Direct docking supported
|