| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019401
BDB019401
|
US10730870, Example 77
COc1cccc(CCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)c1
|
C32H40N4O5S 592.762000 |
FKLIIDWOMMJUOM-DOBADDLBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454910; PubChem:CID122528942
|
Local ready
Direct docking supported
|
|
E3L019402
BDB019402
|
US10730870, Example 78
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccn2)C(C)(C)C)cc1
|
C28H33N5O4S 535.670000 |
GENALQNUPMUAKG-JCTONOIOSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454911; PubChem:CID122528917
|
Local ready
Direct docking supported
|
|
E3L019403
BDB019403
|
US10730870, Example 79
CC(C)[C@@H](C(=O)N1C[C@](C)(O)C[C@H]1C(=O)O)N1Cc2ccccc2C1=O
|
C19H24N2O5 360.410000 |
QUBUYLUWNCJKOM-YZVOILCLSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454912; PubChem:CID122528936
|
Local ready
Direct docking supported
|
|
E3L019404
BDB019404
|
US10730870, Example 80
Cc1cnccc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C31H34N4O4 526.637000 |
YYJKUNBEMJVWFB-KGPYPHOUSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454913; PubChem:CID122529224
|
Local ready
Direct docking supported
|
|
E3L019405
BDB019405
|
US10730870, Example 81
COc1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C26H31N3O5 465.550000 |
PDXUBEWQSIEGOD-OIBXWCBGSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454914; PubChem:CID122528980
|
Local ready
Direct docking supported
|
|
E3L019406
BDB019406
|
US10730870, Example 82
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)c(F)c1
|
C29H31FN4O4S 550.656000 |
XBPOOTKQGYFSFH-ZODMCCGTSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454915; PubChem:CID122529189
|
Local ready
Direct docking supported
|
|
E3L019407
BDB019407
|
US10730870, Example 83
COc1ccccc1CCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C
|
C32H40N4O5S 592.762000 |
ORYIAYLKBQJOHH-BEYSDYMESA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454916; PubChem:CID122529235
|
Local ready
Direct docking supported
|
|
E3L019408
BDB019408
|
US10730870, Example 84
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2cccnc2)C(C)(C)C)cc1
|
C28H33N5O4S 535.670000 |
MUJBSIOEGFOHBE-AOHZBQACSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454917; PubChem:CID122529034
|
Local ready
Direct docking supported
|
|
E3L019409
BDB019409
|
US10730870, Example 86
CC(=O)NCC(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C20H24N4O4S 416.503000 |
BKKFHZVHSZJOJS-SJORKVTESA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454919; PubChem:CID122529219
|
Local ready
Direct docking supported
|
|
E3L019410
BDB019410
|
US10730870, Example 87
CC(=O)O[C@@H](C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C21H25N3O5S 431.514000 |
KBZQCHCLOJYNTO-VHSSKADRSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454920; PubChem:CID89690747
|
Local ready
Direct docking supported
|
|
E3L019411
BDB019411
|
US10730870, Example 88
COc1ccc(C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)c(C)c1
|
C25H27N3O4S 465.575000 |
JTKHEMDQUGUNOU-KNQAVFIVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454921; PubChem:CID122528914
|
Local ready
Direct docking supported
|
|
E3L019412
BDB019412
|
US10730870, Example 89
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C(N)C(F)(F)F)cc1
|
C19H21F3N4O3S 442.463000 |
FNBHJRUQIBKBLR-CNYCQXTOSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454922; PubChem:CID122529018
|
Local ready
Direct docking supported
|
|
E3L019413
BDB019413
|
US10730870, Example 90
CC(=O)NC(C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(F)(F)F
|
C21H23F3N4O4S 484.500000 |
QFIBPTJZUZOBKU-LNKXUWQBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454923; PubChem:CID122529223
|
Local ready
Direct docking supported
|
|
E3L019414
BDB019414
|
US10730870, Example 91
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(N2CCOCC2)cc1)N1Cc2ccccc2C1=O
|
C29H36N4O5 520.630000 |
CJRVBIQPTLOGFS-AFESJLNVSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454924; PubChem:CID122529206
|
Local ready
Direct docking supported
|
|
E3L019415
BDB019415
|
US10730870, Example 92
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2ccnn2C)cc1)N1Cc2ccccc2C1=O
|
C29H33N5O4 515.614000 |
DEEILZWFZPBMKY-RZFJZAQRSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454925; PubChem:CID122528958
|
Local ready
Direct docking supported
|
|
E3L019416
BDB019416
|
US10730870, Example 93
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1F
|
C29H31FN4O4S 550.656000 |
DSNGWORZYXGRCK-YNJKOYDBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454926; PubChem:CID122529153
|
Local ready
Direct docking supported
|
|
E3L019417
BDB019417
|
US10730870, Example 94
CC[C@H](C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)N1Cc2ccc(F)cc2C1=O
|
C30H33FN4O4S 564.683000 |
BADMTEFLTGIPRJ-NMCMYWIVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454927; PubChem:CID122529196
|
Local ready
Direct docking supported
|
|
E3L019418
BDB019418
|
US10730870, Example 95
COc1ccc(C)c(C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)c1
|
C25H27N3O4S 465.575000 |
URTYDBFSZYOXSY-KNQAVFIVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454928; PubChem:CID122528972
|
Local ready
Direct docking supported
|
|
E3L019419
BDB019419
|
US10730870, Example 96
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2cncn2C)cc1)N1Cc2ccccc2C1=O
|
C29H33N5O4 515.614000 |
KIVPCBMSZJYPOT-CWDLOFLHSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454929; PubChem:CID122529004
|
Local ready
Direct docking supported
|
|
E3L019420
BDB019420
|
US10730870, Example 97
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2cncs2)cc1)N1Cc2ccccc2C1=O
|
C28H30N4O4S 518.639000 |
HPQQXUHHJMDFGG-VTZPFEBOSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454930; PubChem:CID122529022
|
Local ready
Direct docking supported
|