| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019361
BDB019361
|
US10730870, Example 32
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NCCC(C)C)C2CCCC2)cc1
|
C28H40N4O3S 512.720000 |
LBWXPENBLGROEU-DSITVLBTSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454869; PubChem:CID122528985
|
Local ready
Direct docking supported
|
|
E3L019362
BDB019362
|
US10730870, Example 33
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3c(F)cccc3C2=O)cc1
|
C29H31FN4O4S 550.656000 |
KFWCDEUBKRIYPP-YNJKOYDBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454870; PubChem:CID122529017
|
Local ready
Direct docking supported
|
|
E3L019363
BDB019363
|
US10730870, Example 34
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3cc(C#N)ccc3C2=O)cc1
|
C30H31N5O4S 557.676000 |
QEVBIPGACHQDQE-AFESJLNVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454871; PubChem:CID122529227
|
Local ready
Direct docking supported
|
|
E3L019364
BDB019364
|
US10730870, Example 35
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3c(C#N)cccc3C2=O)cc1
|
C30H31N5O4S 557.676000 |
LRZZTYVIZNQTND-RZFJZAQRSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454872; PubChem:CID122528984
|
Local ready
Direct docking supported
|
|
E3L019365
BDB019365
|
US10730870, Example 36
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCCCC2)C(C)(C)C)cc1
|
C29H40N4O4S 540.730000 |
HSEHJNACVZBYIS-GIFXNVAJSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454873; PubChem:CID122529083
|
Local ready
Direct docking supported
|
|
E3L019366
BDB019366
|
US10730870, Example 37
CSC[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)N1Cc2ccccc2C1=O
|
C28H30N4O4S2 550.706000 |
SAEAHPBBNLJBRH-NHTMILBNSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454874; PubChem:CID122529011
|
Local ready
Direct docking supported
|
|
E3L019367
BDB019367
|
US10730870, Example 38
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C2CCCC2)N2Cc3ccccc3C2=O)cc1
|
C31H34N4O4S 558.704000 |
YMRFUSDFDQZOFK-STXQHDJLSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454875; PubChem:CID122529132
|
Local ready
Direct docking supported
|
|
E3L019368
BDB019368
|
US10730870, Example 39
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C30H34N4O4S 546.693000 |
NRFUNIWQTXTAPE-JYCYPEEHSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454876; PubChem:CID122529005
|
Local ready
Direct docking supported
|
|
E3L019369
BDB019369
|
US10730870, Example 40
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2ccccc2)cc1)N1Cc2ccccc2C1=O
|
C31H33N3O4 511.622000 |
SFSXLCBUFCGBJV-PKXQUSJVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454877; PubChem:CID122529185
|
Local ready
Direct docking supported
|
|
E3L019370
BDB019370
|
BDBM454878
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2ccn[nH]2)cc1)N1Cc2ccccc2C1=O
|
C28H31N5O4 501.587000 |
XYQVMKXFOOMQAE-ZODMCCGTSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454878; PubChem:CID122529084
|
Local ready
Direct docking supported
|
|
E3L019371
BDB019371
|
US10730870, Example 42
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3cccc(Br)c3C2=O)cc1
|
C29H31BrN4O4S 611.562000 |
LXXLDGNKXVDXIO-VTZPFEBOSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454879; PubChem:CID122529228
|
Local ready
Direct docking supported
|
|
E3L019372
BDB019372
|
US10730870, Example 43
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccc(C#N)cc2)C(C)(C)C)cc1
|
C30H33N5O4S 559.692000 |
LMUZJDMUBMCIBC-RMTZWNOUSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454880; PubChem:CID122529246
|
Local ready
Direct docking supported
|
|
E3L019373
BDB019373
|
US10730870, Example 44
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCc2ccccc2)C(C)(C)C)cc1
|
C31H38N4O4S 562.736000 |
LZOHYKPBMBVPRQ-CERRFVOPSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454881; PubChem:CID122529085
|
Local ready
Direct docking supported
|
|
E3L019374
BDB019374
|
US10730870, Example 45
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]([C@H](C)O)N2Cc3ccccc3C2=O)cc1
|
C28H30N4O5S 534.638000 |
BMBWDWRJLPGOLE-UTZTXDCNSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454882; PubChem:CID122529108
|
Local ready
Direct docking supported
|
|
E3L019375
BDB019375
|
US10730870, Example 46
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C(C)(C)N2Cc3ccccc3C2=O)cc1
|
C28H30N4O4S 518.639000 |
YTRGLAJTSDIEPI-GGAORHGYSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454883; PubChem:CID122528919
|
Local ready
Direct docking supported
|
|
E3L019376
BDB019376
|
US10730870, Example 47
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3cccc(C#N)c3C2=O)cc1
|
C30H31N5O4S 557.676000 |
FLXRXNAKENRCSS-USZFVNFHSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454884; PubChem:CID122529195
|
Local ready
Direct docking supported
|
|
E3L019377
BDB019377
|
US10730870, Example 48
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](CS)N2Cc3ccccc3C2=O)cc1
|
C27H28N4O4S2 536.679000 |
VVJLUQNRZOJCMK-PUHATCMVSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454885; PubChem:CID122528990
|
Local ready
Direct docking supported
|
|
E3L019378
BDB019378
|
US10730870, Example 49
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C2(N3Cc4ccccc4C3=O)CC2)cc1
|
C28H28N4O4S 516.623000 |
QDXBUKNZQKWECA-GGAORHGYSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454886; PubChem:CID122529220
|
Local ready
Direct docking supported
|
|
E3L019379
BDB019379
|
US10730870, Example 50
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C2(N3Cc4ccccc4C3=O)CCCC2)cc1
|
C30H32N4O4S 544.677000 |
PXVPRLIAUDMNCB-NOZRDPDXSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454887; PubChem:CID122528969
|
Local ready
Direct docking supported
|
|
E3L019380
BDB019380
|
US10730870, Example 51
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCC(C)C)[C@H](C)O)cc1
|
C26H36N4O5S 516.664000 |
DPZAUJYQMWDFAV-OOIKZJQMSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454888; PubChem:CID122528912
|
Local ready
Direct docking supported
|