| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019421
BDB019421
|
US10730870, Example 98
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2CCCC2=O)cc1
|
C25H32N4O4S 484.622000 |
GZEABFFQYSWWIQ-URVUXULASA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454931; PubChem:CID122529025
|
Local ready
Direct docking supported
|
|
E3L019422
BDB019422
|
US10730870, Example 99
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ncccc3C2=O)cc1
|
C28H31N5O4S 533.654000 |
PCDKDIQCUMWKIP-QDSKXPNFSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454932; PubChem:CID122529099
|
Local ready
Direct docking supported
|
|
E3L019423
BDB019423
|
BDBM454933
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2cnn[nH]2)cc1)N1Cc2ccccc2C1=O
|
C27H30N6O4 502.575000 |
ZBSJJPPJBHUJCJ-QDSKXPNFSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454933; PubChem:CID122538508
|
Local ready
Direct docking supported
|
|
E3L019424
BDB019424
|
US10730870, Example 101
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2ncon2)cc1)N1Cc2ccccc2C1=O
|
C27H29N5O5 503.559000 |
VKVAUVXKZZNVEO-PUHATCMVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454934; PubChem:CID122529211
|
Local ready
Direct docking supported
|
|
E3L019425
BDB019425
|
US10730870, Example 102
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C(F)(F)F)cc1)N1Cc2ccccc2C1=O
|
C29H29F3N4O4S 586.636000 |
FEQYFWWATDFOMX-PUHATCMVSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454935; PubChem:CID122528926
|
Local ready
Direct docking supported
|
|
E3L019426
BDB019426
|
US10730870, Example 103
Cc1ncn(C)c1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C30H35N5O4 529.641000 |
QSCOPWFYHSWYNM-AFESJLNVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454936; PubChem:CID122528922
|
Local ready
Direct docking supported
|
|
E3L019427
BDB019427
|
US10730870, Example 104
CC[C@H](C)[C@H](NCCc1ccccc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C30H38N4O3S 534.726000 |
QGUGPQZSTUMLQR-JYIOINSGSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454937; PubChem:CID122528965
|
Local ready
Direct docking supported
|
|
E3L019428
BDB019428
|
US10730870, Example 105
CC[C@H](C)[C@H](NC(C)c1ccccc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C30H38N4O3S 534.726000 |
AXZJILSTQJORSE-YLQURUFKSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454938; PubChem:CID122528913
|
Local ready
Direct docking supported
|
|
E3L019429
BDB019429
|
US10730870, Example 106
Cc1c(-c2ccc(CNC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](C(C)C)N3Cc4ccccc4C3=O)cc2)ncn1C
|
C30H35N5O4 529.641000 |
NOADDOKSHFVTFJ-NIYJGHKDSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454939; PubChem:CID122529115
|
Local ready
Direct docking supported
|
|
E3L019430
BDB019430
|
US10730870, Example 107
CC[C@H](NC(C)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C22H28N4O4S 444.557000 |
BBJYPVWFVYKSNF-QYZOEREBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454940; PubChem:CID117719924
|
Local ready
Direct docking supported
|
|
E3L019431
BDB019431
|
US10730870, Example 109
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2c2cccc(Oc3ccccc3)c2)cc1
|
C28H27N3O3S 485.609000 |
OCFBQOXLIKYFDS-BVAGGSTKSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454942; PubChem:CID122528948
|
Local ready
Direct docking supported
|
|
E3L019432
BDB019432
|
US10730870, Example 111
COC1=CC(=O)N([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)C)C1
|
C26H32N4O5S 512.632000 |
GTVIVAIUGKIIDT-NWSQWKLXSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454944; PubChem:CID122529102
|
Local ready
Direct docking supported
|
|
E3L019433
BDB019433
|
US10730870, Example 112
Cc1ncsc1-c1ccc(CN/C(=N/C#N)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C30H32N6O3S 556.692000 |
ASIGVMUYFSRLLF-AFESJLNVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454945; PubChem:CID122529072
|
Local ready
Direct docking supported
|
|
E3L019434
BDB019434
|
US10730870, Example 113
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2CC2)cc1)N1Cc2ccccc2C1=O
|
C28H33N3O4 475.589000 |
LXFCPUZPELNTFA-VJTSUQJLSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454946; PubChem:CID122529053
|
Local ready
Direct docking supported
|
|
E3L019435
BDB019435
|
US10730870, Example 114
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2CCC2)cc1)N1Cc2ccccc2C1=O
|
C29H35N3O4 489.616000 |
XLQZZKABSZPYAJ-AFESJLNVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454947; PubChem:CID122529201
|
Local ready
Direct docking supported
|
|
E3L019436
BDB019436
|
US10730870, Example 115
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2CCCC2)cc1)N1Cc2ccccc2C1=O
|
C30H37N3O4 503.643000 |
QSGNQAQPOMGOHI-STXQHDJLSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454948; PubChem:CID122529052
|
Local ready
Direct docking supported
|
|
E3L019437
BDB019437
|
US10730870, Example 116
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2=CCCC2)cc1)N1Cc2ccccc2C1=O
|
C30H35N3O4 501.627000 |
ZTDMSABBFAEYOW-STXQHDJLSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454949; PubChem:CID122528989
|
Local ready
Direct docking supported
|
|
E3L019438
BDB019438
|
US10730870, Example 117
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2CCCCC2)cc1)N1Cc2ccccc2C1=O
|
C31H39N3O4 517.670000 |
RXKTWNNRVGVJPG-PKXQUSJVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454950; PubChem:CID122529013
|
Local ready
Direct docking supported
|
|
E3L019439
BDB019439
|
US10730870, Example 118
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2CCOCC2)cc1)N1Cc2ccccc2C1=O
|
C30H37N3O5 519.642000 |
MPMNCQPWYGFQAN-STXQHDJLSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454951; PubChem:CID122528953
|
Local ready
Direct docking supported
|
|
E3L019440
BDB019440
|
US10730870, Example 120
CO/N=C(/NCc1ccc(-c2scnc2C)cc1)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)C)N1Cc2ccccc2C1=O
|
C30H35N5O4S 561.708000 |
PTOLTNIVIBFTGK-AFESJLNVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454952; PubChem:CID122529116
|
Local ready
Direct docking supported
|