| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019341
BDB019341
|
US10730870, Example 11
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccc(Br)cc3C2=O)cc1
|
C29H31BrN4O4S 611.562000 |
ZVUFLGVKYVCKFG-VJTSUQJLSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454848; PubChem:CID122529142
|
Local ready
Direct docking supported
|
|
E3L019342
BDB019342
|
US10730870, Example 13
CCCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C
|
C26H36N4O4S 500.665000 |
WLNJESDHZIGLKM-ZRCGQRJVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454850; PubChem:CID122529070
|
Local ready
Direct docking supported
|
|
E3L019343
BDB019343
|
US10730870, Example 14
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(C)(C)C)C(C)(C)C)cc1
|
C27H38N4O4S 514.692000 |
BDJXRJAHFHEPLB-RZUBCFFCSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454851; PubChem:CID122529159
|
Local ready
Direct docking supported
|
|
E3L019344
BDB019344
|
US10730870, Example 15
COc1cccc2c1C(=O)N([C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c3scnc3C)cc1)C(C)C)C2
|
C30H34N4O5S 562.692000 |
OOJPKSNELSHOJZ-UMFSSWHCSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454852; PubChem:CID122529210
|
Local ready
Direct docking supported
|
|
E3L019345
BDB019345
|
US10730870, Example 16
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3cc(F)ccc3C2=O)cc1
|
C29H31FN4O4S 550.656000 |
SFZYCFJYAYHUKT-VJTSUQJLSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454853; PubChem:CID122529250
|
Local ready
Direct docking supported
|
|
E3L019346
BDB019346
|
US10730870, Example 17
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccc(C#N)cc3C2=O)cc1
|
C30H31N5O4S 557.676000 |
AUKCLGZXQGRCNV-AFESJLNVSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454854; PubChem:CID122528939
|
Local ready
Direct docking supported
|
|
E3L019347
BDB019347
|
US10730870, Example 18
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CC(C)C)C(C)(C)C)cc1
|
C27H38N4O4S 514.692000 |
FEEFVTMBJHCHIE-ZFGGDYGUSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454855; PubChem:CID122529036
|
Local ready
Direct docking supported
|
|
E3L019348
BDB019348
|
(S,R,S)-AHPC-CO-C-cyclohexane
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CC2CCCCC2)C(C)(C)C)cc1
|
C30H42N4O4S 554.757000 |
YCTQBQRSFGVCDE-ONBPZOJHSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454856; PubChem:CID122529110
|
Local ready
Direct docking supported
|
|
E3L019349
BDB019349
|
US10730870, Example 20
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCC2CCCCC2)C(C)(C)C)cc1
|
C31H44N4O4S 568.784000 |
KGIHOLKJYPBHKG-CERRFVOPSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454857; PubChem:CID122528915
|
Local ready
Direct docking supported
|
|
E3L019350
BDB019350
|
(S,R,S)-AHPC-phenylacetic acid
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)Cc2ccccc2)C(C)(C)C)cc1
|
C30H36N4O4S 548.709000 |
GAUPKVQHAPDXDP-ONBPZOJHSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454858; PubChem:CID122529112
|
Local ready
Direct docking supported
|
|
E3L019351
BDB019351
|
US10730870, Example 22
CSC[C@H](NC(=O)CCC(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C26H36N4O4S2 532.732000 |
VDESLTPJMGJHJZ-FSSWDIPSSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454859; PubChem:CID122529007
|
Local ready
Direct docking supported
|
|
E3L019352
BDB019352
|
US10730870, Example 23
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(Br)cc1)N1Cc2ccccc2C1=O
|
C25H28BrN3O4 514.420000 |
GBDJQICBAQOICA-HJNYFJLDSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454860; PubChem:CID122529234
|
Local ready
Direct docking supported
|
|
E3L019353
BDB019353
|
US10730870, Example 24
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(Br)cc1)N1Cc2ccccc2C1=O
|
C26H30BrN3O4 528.447000 |
HMHXRZASSUKLFH-MWHIGSEQSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454861; PubChem:CID122529233
|
Local ready
Direct docking supported
|
|
E3L019354
BDB019354
|
US10730870, Example 25
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3cc(Br)ccc3C2=O)cc1
|
C29H31BrN4O4S 611.562000 |
JMVWFPZRNUOXKD-VJTSUQJLSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454862; PubChem:CID122529179
|
Local ready
Direct docking supported
|
|
E3L019355
BDB019355
|
US10730870, Example 26
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3c(Br)cccc3C2=O)cc1
|
C29H31BrN4O4S 611.562000 |
GVGRVMHQPPDFKJ-YNJKOYDBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454863; PubChem:CID122529143
|
Local ready
Direct docking supported
|
|
E3L019356
BDB019356
|
US10730870, Example 27
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(C)C)C(C)(C)C)cc1
|
C26H36N4O4S 500.665000 |
CAFPUERSNMOOTE-RZUBCFFCSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454864; PubChem:CID122529026
|
Local ready
Direct docking supported
|
|
E3L019357
BDB019357
|
US10730870, Example 28
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCC(C)C)C(C)(C)C)cc1
|
C28H40N4O4S 528.719000 |
FQUBAGYWCJIYHA-OTNCWRBYSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454865; PubChem:CID122529141
|
Local ready
Direct docking supported
|
|
E3L019358
BDB019358
|
US10730870, Example 29
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccc2)C(C)(C)C)cc1
|
C29H34N4O4S 534.682000 |
KLBZQDSKHPUBJP-GIFXNVAJSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454866; PubChem:CID122528999
|
Local ready
Direct docking supported
|
|
E3L019359
BDB019359
|
US10730870, Example 30
CC[C@H](C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)N1Cc2ccccc2C1=O
|
C30H34N4O4S 546.693000 |
SEXYQPBYWZVVSL-JYCYPEEHSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454867; PubChem:CID122528935
|
Local ready
Direct docking supported
|
|
E3L019360
BDB019360
|
US10730870, Example 31
CC[C@H](C)[C@H](NC(=O)CCC(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1
|
C28H40N4O4S 528.719000 |
GYXAUHPUDYQGAZ-SEBHOYJNSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454868; PubChem:CID122529033
|
Local ready
Direct docking supported
|