| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019441
BDB019441
|
US10730870, Example 121
Cc1ncsc1-c1ccc(CNC[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C29H34N4O3S 518.683000 |
OHHQWLNQEJPZQB-GSLIJJQTSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454953; PubChem:CID122529074
|
Local ready
Direct docking supported
|
|
E3L019442
BDB019442
|
US10730870, Example 122
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)(C)C)cc1
|
C30H43N5O6S 601.770000 |
SIYKQIOZRBLSPF-STCFVSJZSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454954; PubChem:CID122550989
|
Local ready
Direct docking supported
|
|
E3L019443
BDB019443
|
US10730870, Example 123
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)(C)C)cc1
|
C25H35N5O4S 501.653000 |
YLFNLUHMLHXZSZ-SDWXPCGYSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454955; PubChem:CID122529096
|
Local ready
Direct docking supported
|
|
E3L019444
BDB019444
|
VH032-NH-CO-CH2-NHBoc
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)(C)C)cc1
|
C29H41N5O6S 587.743000 |
VTKNFMYABFTAQP-ZFGGDYGUSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454956; PubChem:CID122529104
|
Local ready
Direct docking supported
|
|
E3L019445
BDB019445
|
(S,R,S)-Ahpc-C1-NH2
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CN)C(C)(C)C)cc1
|
C24H33N5O4S 487.626000 |
JCICRLSKTBKTGL-LVCYWYKZSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454957; PubChem:CID122529240
|
Local ready
Direct docking supported
|
|
E3L019446
BDB019446
|
US10730870, Example 126
Cc1ncsc1-c1ccc(CNC(=N)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C29H33N5O3S 531.682000 |
HBNQYNNIXDSMQE-VJTSUQJLSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454958; PubChem:CID122529097
|
Local ready
Direct docking supported
|
|
E3L019447
BDB019447
|
US10730870, Example 127
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2(O)COC2)cc1)N1Cc2ccccc2C1=O
|
C28H33N3O6 507.587000 |
BGZKKLDCVYTKEE-NHTMILBNSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454959; PubChem:CID122529174
|
Local ready
Direct docking supported
|
|
E3L019448
BDB019448
|
US10730870, Example 128
Cc1ncsc1-c1ccc(CNC(=O)C2(C)C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C30H34N4O4S 546.693000 |
CWWBCISTWBLCMI-CGYACHGYSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454960; PubChem:CID122550988
|
Local ready
Direct docking supported
|
|
E3L019449
BDB019449
|
US10730870, Example 130
CC(=O)N[C@H](C(=S)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)C
|
C23H30N4O3S2 474.652000 |
VHBITMCQHKMGGJ-AABGKKOBSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454962; PubChem:CID122529048
|
Local ready
Direct docking supported
|
|
E3L019450
BDB019450
|
US10730870, Example 133
Cc1ncoc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C29H32N4O5 516.598000 |
QKBCDUISQZTJFO-VJTSUQJLSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454964; PubChem:CID122529064
|
Local ready
Direct docking supported
|
|
E3L019451
BDB019451
|
US10730870, Example 134
CC(=O)N(C)[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)C
|
C24H32N4O4S 472.611000 |
BCQQTYRJCKNNEA-HKBOAZHASA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454965; PubChem:CID122529187
|
Local ready
Direct docking supported
|
|
E3L019452
BDB019452
|
US10730870, Example 136
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2ccno2)cc1)N1Cc2ccccc2C1=O
|
C28H30N4O5 502.571000 |
BMDMKOJTORHUHU-VTZPFEBOSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454967; PubChem:CID122529183
|
Local ready
Direct docking supported
|
|
E3L019453
BDB019453
|
US10730870, Example 137
CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2cnoc2)cc1)N1Cc2ccccc2C1=O
|
C28H30N4O5 502.571000 |
WYVZEJWRHSNNMU-VJTSUQJLSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454968; PubChem:CID122529089
|
Local ready
Direct docking supported
|
|
E3L019454
BDB019454
|
US10730870, Example 145
Cc1cc([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)C)on1
|
C25H30N4O4S 482.606000 |
LIUCLKNTUXMZEI-RZUBCFFCSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454969; PubChem:CID122529123
|
Local ready
Direct docking supported
|
|
E3L019455
BDB019455
|
US10730870, Example 139
Cc1cc([C@H](C)C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)on1
|
C23H26N4O4S 454.552000 |
LLBLDVFFCNUTQR-KYNGSXCRSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454970; PubChem:CID122529158
|
Local ready
Direct docking supported
|
|
E3L019456
BDB019456
|
US10730870, Example 140
Cc1cc(C(C)(C)C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)on1
|
C24H28N4O4S 468.579000 |
BCVYJRNKQQMGAR-MOPGFXCFSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454971; PubChem:CID122529100
|
Local ready
Direct docking supported
|
|
E3L019457
BDB019457
|
US10730870, Example 141
Cc1cc(C(C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)C)on1
|
C25H30N4O4S 482.606000 |
LIUCLKNTUXMZEI-MFCMXAAESA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454972; PubChem:CID122528974
|
Local ready
Direct docking supported
|
|
E3L019458
BDB019458
|
US10730870, Example 142
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@](C)(O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1
|
C30H34N4O4S 546.693000 |
HQFKQSUJYIWMNN-SAGWHXFDSA-N | P40337, P62877, Q13617 | Cullin-2, von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454973; PubChem:CID122529068
|
Local ready
Direct docking supported
|
|
E3L019459
BDB019459
|
US10730870, Example 143
CCC(C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)c1cc(C)no1
|
C24H28N4O4S 468.579000 |
ZGOLSNHYXOMXQC-ITIDOPETSA-N | P40337, P62877, Q13617 | von Hippel-Lindau disease tumor suppressor, Cullin-2 |
BindingDB, PubChem
BindingDB:BDBM454974; PubChem:CID122528921
|
Local ready
Direct docking supported
|
|
E3L019460
BDB019460
|
US10730870, Example 145
Cc1cc([C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)C)on1
|
C25H30N4O4S 482.606000 |
LIUCLKNTUXMZEI-RZUBCFFCSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, PubChem
BindingDB:BDBM454975; PubChem:CID122529123
|
Local ready
Direct docking supported
|