| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019501
BDB019501
|
BDBM464550
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(CCC)cc(C)[nH]c4=O)cc(-c4ccc(N5C=CN(C)C=C5)nc4)cc32)CC1
|
C36H40N6O4S 652.821000 |
OJEZJWDIBGFFMT-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464550; PubChem:CID177666681
|
Local ready
Direct docking supported
|
|
E3L019502
BDB019502
|
BDBM464551
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(N)nc4)cc32)CC1
|
C29H31N5O5S 561.664000 |
QTPQMGNCWCCIHN-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464551; PubChem:CID139543600
|
Local ready
Direct docking supported
|
|
E3L019503
BDB019503
|
BDBM464552
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(CCC(C)C)nc4)cc32)CC1
|
C33H38N4O6S 618.756000 |
DZXKUGJTQQFYJV-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464552; PubChem:CID177668499
|
Local ready
Direct docking supported
|
|
E3L019504
BDB019504
|
BDBM464553
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(N(C)C)nc4)cc32)CC1
|
C30H33N5O6S 591.690000 |
VJSKJBCRWCKMOV-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464553; PubChem:CID177667094
|
Local ready
Direct docking supported
|
|
E3L019505
BDB019505
|
BDBM464554
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4cncc(N5CCN(C)CC5)c4)cc32)CC1
|
C33H38N6O6S 646.770000 |
GSGYZQJGPTXSRX-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464554
|
Local ready
Direct docking supported
|
|
E3L019506
BDB019506
|
BDBM464555
C=CCC1(S(=O)(=O)n2cc(Cl)c3c(C(=O)NCc4c(Cl)cc(C)[nH]c4=O)cc(-c4cnc(N5C=CN(C(C)C)C=C5)nc4)cc32)CC1
|
C33H33Cl2N7O4S 694.645000 |
FDGNPMJCDIJXOQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464555
|
Local ready
Direct docking supported
|
|
E3L019507
BDB019507
|
BDBM464556
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(N5C=CN(CC(C)(F)F)C=C5)nc4)cc32)CC1
|
C36H38F2N6O4S 688.801000 |
RYFHKRACOHEEPD-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464556
|
Local ready
Direct docking supported
|
|
E3L019508
BDB019508
|
BDBM464558
C=CCC1(S(=O)(=O)n2cc(Cl)c3c(C(=O)NCc4c(Cl)cc(C)[nH]c4=O)cc(-c4ccc(N5C=CN(CC(C)(F)F)C=C5)nc4)cc32)CC1
|
C34H32Cl2F2N6O4S 729.637000 |
QOYBYCVGYWVUIM-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464558
|
Local ready
Direct docking supported
|
|
E3L019509
BDB019509
|
BDBM464559
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(O)cc(C)[nH]c4=O)cc(-c4ccnc(N5CCN(C)CC5)c4)cc32)CC1
|
C32H36N6O6S 632.743000 |
YWLLOMMLWQWASK-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464559
|
Local ready
Direct docking supported
|
|
E3L019510
BDB019510
|
BDBM464561
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(N5CCN(C(C)C)CC5)nc4)cc32)CC1
|
C36H44N6O4S 656.853000 |
ZLEVWZJBARHVGV-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464561; PubChem:CID139530055
|
Local ready
Direct docking supported
|
|
E3L019511
BDB019511
|
BDBM464562
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(N5CCNCC5)nc4)cc32)CC1
|
C32H36N6O6S 632.743000 |
WAKNXLQHJPZLOV-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464562; PubChem:CID172636620
|
Local ready
Direct docking supported
|
|
E3L019512
BDB019512
|
BDBM464563
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4cnc(N5CCNCC5)nc4)cc32)CC1
|
C32H37N7O4S 615.760000 |
LPZRXANKEJXKFQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464563; PubChem:CID139543593
|
Local ready
Direct docking supported
|
|
E3L019513
BDB019513
|
BDBM464564
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4cnc(N5CCN(C(C)C)CC5)nc4)cc32)CC1
|
C35H43N7O5S 673.840000 |
KFBDQUMEGVZMJM-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464564
|
Local ready
Direct docking supported
|
|
E3L019514
BDB019514
|
BDBM464565
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC(F)F)cc(C)nc4OCc4ccccc4)cc(-c4ccc(N5CCN(C)CC5)nc4)cc32)CC1
|
C41H44F2N6O5S 770.903000 |
HFKYKTAWQXMWGQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464565
|
Local ready
Direct docking supported
|
|
E3L019515
BDB019515
|
BDBM464566
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(N4CCN(C)CC4)cc32)CC1
|
C29H37N5O5S 567.712000 |
OPDSDRNDYJKMNU-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464566; PubChem:CID139543666
|
Local ready
Direct docking supported
|
|
E3L019516
BDB019516
|
BDBM464567
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(N4C=CN(CC(C)(F)F)C=C4)cc32)CC1
|
C31H35F2N5O5S 627.714000 |
XKZOVUPFXXUUBM-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464567; PubChem:CID177668182
|
Local ready
Direct docking supported
|
|
E3L019517
BDB019517
|
BDBM464568
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(N4C=CN(C(C)C)C=C4)cc32)CC1
|
C31H37N5O5S 591.734000 |
ZNUCFGBUOACYBF-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464568; PubChem:CID177667771
|
Local ready
Direct docking supported
|
|
E3L019518
BDB019518
|
BDBM464569
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(N4C=CN(C)C(C)=C4)cc32)CC1
|
C30H35N5O5S 577.707000 |
YTCYIIQKVJFDTA-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464569; PubChem:CID177667647
|
Local ready
Direct docking supported
|
|
E3L019519
BDB019519
|
BDBM464570
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(N4C=CN(CC)C=C4)cc32)CC1
|
C30H35N5O5S 577.707000 |
KOLUAFMFXXTAKO-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464570; PubChem:CID177668408
|
Local ready
Direct docking supported
|
|
E3L019520
BDB019520
|
BDBM464571
C=CCC1(S(=O)(=O)n2ccc3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(N5CCN(C)CC5)nc4)cc32)CC1
|
C33H38N6O4S 614.772000 |
GBXMRSWKFIOOTI-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464571; PubChem:CID147610544
|
Local ready
Direct docking supported
|