| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L019481
BDB019481
|
BDBM464527
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4cnc(N5CCN(C)CC5)nc4)cc32)CC1
|
C33H39N7O4S 629.787000 |
RHLOKPGCUAJRJZ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464527; PubChem:CID139543592
|
Local ready
Direct docking supported
|
|
E3L019482
BDB019482
|
BDBM464528
C=CCC1(S(=O)(=O)n2cc(OC)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(N5CCN(C)CC5)nc4)cc32)CC1
|
C34H40N6O5S 644.798000 |
YYISXYQDJFLQEA-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464528; PubChem:CID177666042
|
Local ready
Direct docking supported
|
|
E3L019483
BDB019483
|
BDBM464529
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(CN(C)C)cc4F)cc32)CC1
|
C33H37FN4O4S 604.748000 |
CTACORXSFACCEC-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464529; PubChem:CID139543618
|
Local ready
Direct docking supported
|
|
E3L019484
BDB019484
|
BDBM464530
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(CN(C)C)c(F)c4)cc32)CC1
|
C33H37FN4O4S 604.748000 |
LRPCDMLAUKUYGC-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464530; PubChem:CID139543641
|
Local ready
Direct docking supported
|
|
E3L019485
BDB019485
|
BDBM464533
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OCCC)cc(C)[nH]c4=O)cc(-c4ccc(N5CCN(C)CC5)nc4)cc32)CC1
|
C35H42N6O6S 674.824000 |
FXRJBSKKRLSPCJ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464533
|
Local ready
Direct docking supported
|
|
E3L019486
BDB019486
|
BDBM464534
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(N5CCN(C)CC5)nc4)cc32)CC1
|
C33H38N6O6S 646.770000 |
QZTPVNUENBWUPE-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464534
|
Local ready
Direct docking supported
|
|
E3L019487
BDB019487
|
BDBM464535
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4ccc(F)c(CN(C)C)c4)cc32)CC1
|
C33H37FN4O4S 604.748000 |
FUSWQDWUGFIHOG-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464535; PubChem:CID139543645
|
Local ready
Direct docking supported
|
|
E3L019488
BDB019488
|
BDBM464536
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4cnc(N5CCOCC5)nc4)cc32)CC1
|
C32H36N6O5S 616.744000 |
PWEZXNVUOLJLMU-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464536; PubChem:CID177666157
|
Local ready
Direct docking supported
|
|
E3L019489
BDB019489
|
BDBM464537
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4cnc(N5CCNCC5)nc4)cc32)CC1
|
C31H35N7O6S 633.731000 |
VLGDZXFHUXKWIS-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464537; PubChem:CID177666410
|
Local ready
Direct docking supported
|
|
E3L019490
BDB019490
|
BDBM464538
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(C)cc(C)[nH]c4=O)cc(-c4cnc(N5CC(F)C5)nc4)cc32)CC1
|
C31H33FN6O4S 604.708000 |
YLVLIJLFBVYJID-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464538; PubChem:CID139543688
|
Local ready
Direct docking supported
|
|
E3L019491
BDB019491
|
BDBM464539
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(CC)cc(C)[nH]c4=O)cc(-c4ccc(-c5cn[nH]c5)nc4)cc32)CC1
|
C33H34N6O4S 610.740000 |
ZZRGMOCOQQUTBH-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464539; PubChem:CID177668041
|
Local ready
Direct docking supported
|
|
E3L019492
BDB019492
|
BDBM464540
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(-c5cncnc5)nc4)cc32)CC1
|
C32H30N6O6S 626.695000 |
GZJZUSPKCIJEFD-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464540; PubChem:CID177666763
|
Local ready
Direct docking supported
|
|
E3L019493
BDB019493
|
BDBM464541
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(-c5cccnc5)nc4)cc32)CC1
|
C34H33N5O5S 623.735000 |
GKZOZSJJEZDVED-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464541; PubChem:CID177667029
|
Local ready
Direct docking supported
|
|
E3L019494
BDB019494
|
BDBM464542
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(N5CCN(C)CC5)nc4)cc32)CC1
|
C34H40N6O5S 644.798000 |
PVDOHGHDNKZICQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464542
|
Local ready
Direct docking supported
|
|
E3L019495
BDB019495
|
BDBM464543
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(CN5CCOCC5)nc4)cc32)CC1
|
C33H37N5O7S 647.754000 |
RMTWHRRCJFXDNQ-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464543; PubChem:CID177666275
|
Local ready
Direct docking supported
|
|
E3L019496
BDB019496
|
BDBM464544
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4cnc(N5CC(F)C5)nc4)cc32)CC1
|
C31H33FN6O5S 620.707000 |
ORJYWWNQWIUWOE-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM464544
|
Local ready
Direct docking supported
|
|
E3L019497
BDB019497
|
BDBM464545
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4cncc(F)c4)cc32)CC1
|
C28H27FN4O6S 566.611000 |
CNFZHWQJHARDDP-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464545; PubChem:CID177666426
|
Local ready
Direct docking supported
|
|
E3L019498
BDB019498
|
BDBM464546
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(-c4ccc(CN(C)C)cc4)cc32)CC1
|
C33H38N4O5S 602.757000 |
CSOPDAGIMOCYKX-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464546; PubChem:CID139543692
|
Local ready
Direct docking supported
|
|
E3L019499
BDB019499
|
BDBM464548
C=CCC1(S(=O)(=O)n2cc(O)c3c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc(/C=C/c4ccccn4)cc32)CC1
|
C30H30N4O6S 574.659000 |
CTRPGMNOTNAIIO-CMDGGOBGSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464548; PubChem:CID177667775
|
Local ready
Direct docking supported
|
|
E3L019500
BDB019500
|
BDBM464549
C=CCC1(S(=O)(=O)n2cc(C)c3c(C(=O)NCc4c(Cl)cc(C)[nH]c4=O)cc(-c4ccc(N5C=CN(C)C=C5)nc4)cc32)CC1
|
C33H33ClN6O4S 645.185000 |
CKICBEZFCKVFMM-UHFFFAOYSA-N | O75530 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM464549; PubChem:CID177668228
|
Local ready
Direct docking supported
|