| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023501
BDB023501
|
US11236047, Example 292
CC(=O)N1CCC(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(C#N)cn2)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C35H36ClFN4O5 647.147000 |
ILWWWJCABRTVHO-PWXSHKNQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535342; PubChem:CID135282777
|
Local ready
Direct docking supported
|
|
E3L023502
BDB023502
|
US11236047, Example 171
C[S+]([O-])C1(CO[C@]2(c3ccc(Cl)cc3)c3c(F)cc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cn2)CC1
|
C28H27Cl2FN2O4S 577.505000 |
BMDCWINLUAOPGG-GOGSRFGOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535343; PubChem:CID135282711
|
Local ready
Direct docking supported
|
|
E3L023503
BDB023503
|
US11236047, Example 269
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H27Cl2N3O3 512.437000 |
OZCYVNAYNKYZPN-SSYAZFEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535345; PubChem:CID135282142
|
Local ready
Direct docking supported
|
|
E3L023504
BDB023504
|
US11236047, Example 168
C[C@H](CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1)C(N)=O
|
C27H26Cl2FN3O4 546.426000 |
BQIHMGXSJXBAHX-YVORESIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535347; PubChem:CID135282694
|
Local ready
Direct docking supported
|
|
E3L023505
BDB023505
|
US11236047, Example 175
Cn1cc(C(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cn2)[C@@]3(OCC2(C(N)=O)CC2)c2ccc(Cl)cc2)cn1
|
C30H26Cl2FN5O4 610.473000 |
PHAFDTKHQROBDP-NPRFROTHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535348; PubChem:CID135282380
|
Local ready
Direct docking supported
|
|
E3L023506
BDB023506
|
US11236047, Example 271
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCN(C)[C@@H](C)C3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H34Cl2N4O3 569.533000 |
XDGXLCFSFAEFAF-BUVZGADESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535350; PubChem:CID135282731
|
Local ready
Direct docking supported
|
|
E3L023507
BDB023507
|
US11236047, Example 274
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCN(C)C[C@@H]3C)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H34Cl2N4O3 569.533000 |
OAXQKVNYPRRULT-BUVZGADESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535351; PubChem:CID135282887
|
Local ready
Direct docking supported
|
|
E3L023508
BDB023508
|
US11236047, Example 309
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)c1ccccn1
|
C33H28ClFN4O4 599.062000 |
GBXYQVTUXFUTDE-NFCCVXSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535352; PubChem:CID135282651
|
Local ready
Direct docking supported
|
|
E3L023509
BDB023509
|
US11236047, Example 272
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCN(C)[C@H](C)C3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H34Cl2N4O3 569.533000 |
XDGXLCFSFAEFAF-DVVOHRMSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535353; PubChem:CID135282222
|
Local ready
Direct docking supported
|
|
E3L023510
BDB023510
|
US11236047, Example 178
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cn2)[C@@]3(OCC2(C(N)=O)CC2)c2ccc(Cl)cc2)cn1
|
C31H28Cl2FN5O4 624.500000 |
XMACNOJSFYZIIC-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535354; PubChem:CID135282386
|
Local ready
Direct docking supported
|
|
E3L023511
BDB023511
|
US11236047, Example 145
CNC(=O)C(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OC)c1ccc(Cl)cc1
|
C25H23Cl2N3O4 500.382000 |
WHDQNEDIIFHEHU-WUBHUQEYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535355; PubChem:CID135282706
|
Local ready
Direct docking supported
|
|
E3L023512
BDB023512
|
US11236047, Example 173
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(C#N)cn1
|
C25H21ClFN3O3 465.912000 |
ZMIMOAHXTNUTOH-RUZDIDTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535356; PubChem:CID135283060
|
Local ready
Direct docking supported
|
|
E3L023513
BDB023513
|
US11236047, Example 148
CCNC(=O)C(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OC)c1ccc(Cl)cc1
|
C26H25Cl2N3O4 514.409000 |
KYLDDLUOIYASLH-FXDYGKIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535358; PubChem:CID135282453
|
Local ready
Direct docking supported
|
|
E3L023514
BDB023514
|
US11236047, Example 153
CC(O)C1(CO[C@]2(c3ccc(Cl)cc3)c3c(F)cc(C(C)(C)O)cc3C(=O)N2Cc2ccc(C#N)cn2)CC1
|
C30H29ClFN3O4 550.030000 |
DUDAOHFBLXUQBQ-ZGPRTBGDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535359; PubChem:CID135282549
|
Local ready
Direct docking supported
|
|
E3L023515
BDB023515
|
US11236047, Example 287
CN1CCC(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(C#N)cn2)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C34H36ClFN4O4 619.137000 |
FDQSEIVSQMEFMB-SZFCLFMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535361; PubChem:CID135282603
|
Local ready
Direct docking supported
|
|
E3L023516
BDB023516
|
US11236047, Example 152
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)C(=O)NC(C)C)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H27Cl2N3O4 528.436000 |
SQIISUGGYDTKSQ-SSYAZFEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535362; PubChem:CID135282152
|
Local ready
Direct docking supported
|
|
E3L023517
BDB023517
|
US11236047, Example 345
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cn2)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)cn1
|
C31H29Cl2FN4O4 611.501000 |
PTBQGDBOHCKVRI-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535363; PubChem:CID135282087
|
Local ready
Direct docking supported
|
|
E3L023518
BDB023518
|
US11236047, Example 280
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C33H32ClFN4O5 619.093000 |
JEXOJDCVYWEBKG-NFCCVXSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535365; PubChem:CID135282624
|
Local ready
Direct docking supported
|
|
E3L023519
BDB023519
|
US11236047, Example 131
CCC(O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)C2(OC)c1ccc(Cl)cc1)C1(F)CCN(C)CC1
|
C33H34Cl2F2N2O5 647.546000 |
UASWWYBCWGDNKX-BECFNDGMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535366; PubChem:CID135281559
|
Local ready
Direct docking supported
|
|
E3L023520
BDB023520
|
US11236047, Example 284
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C31H31Cl2FN4O5 629.516000 |
CHZQZTPQTRTMGE-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535368; PubChem:CID135282373
|
Local ready
Direct docking supported
|