| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L034941
BDB034941
|
BDBM701158
O=C(O)CN(c1ccc(N(CC(=O)O)S(=O)(=O)c2c(F)cccc2F)cc1)S(=O)(=O)c1c(F)cccc1F
|
C22H16F4N2O8S2 576.502000 |
OGEQGJXPMJDFOW-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB
BindingDB:BDBM701158
|
Local ready
Direct docking supported
|
|
E3L034942
BDB034942
|
BDBM701159
O=C(O)CN(c1ccc(N(CC(=O)O)S(=O)(=O)c2ccc(Oc3ccccc3)cc2)cc1)S(=O)(=O)c1ccc(Oc2ccccc2)cc1
|
C34H28N2O10S2 688.736000 |
IBEJAJJDUUKCJU-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB
BindingDB:BDBM701159
|
Local ready
Direct docking supported
|
|
E3L034943
BDB034943
|
BDBM701160
O=C(O)CN(c1ccc(N(CC(=O)O)S(=O)(=O)c2ccc3ccccc3c2)cc1)S(=O)(=O)c1ccc2ccccc2c1
|
C30H24N2O8S2 604.662000 |
GABPVRRWVDKCED-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB
BindingDB:BDBM701160
|
Local ready
Direct docking supported
|
|
E3L034944
BDB034944
|
BDBM701161
COc1ccc(S(=O)(=O)N(Cc2nnn[nH]2)c2ccc(N(Cc3nnn[nH]3)S(=O)(=O)c3ccc(OC)cc3)cc2)cc1
|
C24H24N10O6S2 612.654000 |
QXLVOXWNYIEAEL-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB
BindingDB:BDBM701161
|
Local ready
Direct docking supported
|
|
E3L034945
BDB034945
|
Pioglitazone
CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1
|
C19H20N2O3S 356.447000 |
HYAFETHFCAUJAY-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM702010; PubChem:CID4829
|
Local ready
Direct docking supported
|
|
E3L034946
BDB034946
|
US20240365736, Example 11
COCCOCC1COCCN1Cc1ccc(COc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1
|
C29H35N3O7 537.613000 |
STDUYDKQKZRBOM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702899; PubChem:CID172496086
|
Local ready
Direct docking supported
|
|
E3L034947
BDB034947
|
US20240365736, Example 12
COCCCCC1COCCN1Cc1ccc(COc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1
|
C30H37N3O6 535.641000 |
QYYOORVUGPOACD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702900; PubChem:CID172878912
|
Local ready
Direct docking supported
|
|
E3L034948
BDB034948
|
US20240365736, Example 14
COCCNC(=O)C1CCCN(Cc2ccc(COc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)cc2)C1
|
C30H36N4O6 548.640000 |
UWWGSOMFLNRZAX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702901; PubChem:CID172496076
|
Local ready
Direct docking supported
|
|
E3L034949
BDB034949
|
US20240365736, Example 16
COCCCC(=O)C1CCN(Cc2ccc(COc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)cc2)CC1
|
C31H37N3O6 547.652000 |
QTJKSTLCSWRPHO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702902; PubChem:CID172878913
|
Local ready
Direct docking supported
|
|
E3L034950
BDB034950
|
US20240365736, Example 18
COCCNC(=O)C1CCN(Cc2ccc(COc3cccc4c3CN(C3CCC(=O)CC3=O)C4=O)cc2)C1
|
C30H35N3O6 533.625000 |
JYLGTOLSSAUPHO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702903; PubChem:CID172878914
|
Local ready
Direct docking supported
|
|
E3L034951
BDB034951
|
US20240365736, Example 20
COCCOCC1CCN(Cc2ccc(COc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)cc2)CC1
|
C30H37N3O6 535.641000 |
VUUXCYIPKCHKFI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702904; PubChem:CID172496070
|
Local ready
Direct docking supported
|
|
E3L034952
BDB034952
|
US20240365736, Example 21
COCCOc1cc(OCc2ccc(CN3CCOCC3)cc2)c2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2
|
C28H33N3O7 523.586000 |
PJBNYZZSTZBBMG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702905; PubChem:CID172496084
|
Local ready
Direct docking supported
|
|
E3L034953
BDB034953
|
US20240365736, Example 22
COCCCc1cc(COc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)ccc1CN1CCOCC1
|
C29H35N3O6 521.614000 |
CAOFXMJQXIJBGC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702906; PubChem:CID172878915
|
Local ready
Direct docking supported
|
|
E3L034954
BDB034954
|
US20240365736, Example 23
COCCNc1cc(CN2CCOCC2)ccc1COc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O
|
C28H34N4O6 522.602000 |
RGHRTUBGGRCNQN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702907; PubChem:CID172496067
|
Local ready
Direct docking supported
|
|
E3L034955
BDB034955
|
US20240365736, Example 24
COCCCC(=O)c1cc(COc2cccc3c2CN([C@H]2CCC(=O)NC2=O)C3=O)ccc1CN1CCOCC1
|
C30H35N3O7 549.624000 |
FHKFSHQHPBCJDY-VWLOTQADSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM702908; PubChem:CID172878916
|
Local ready
Direct docking supported
|
|
E3L034956
BDB034956
|
US20240368153, Example 1-1
Cc1cc(N)nc2cc(-c3ccccc3)cnc12
|
C15H13N3 235.290000 |
CDSMVLOAJAFUKK-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703854; PubChem:CID172487122
|
Local ready
Direct docking supported
|
|
E3L034957
BDB034957
|
US20240368153, Example 1-2
Cc1cc(N)nc2cc(-c3ccccn3)cnc12
|
C14H12N4 236.278000 |
XGARVOSZCBNAAT-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703871; PubChem:CID172487097
|
Local ready
Direct docking supported
|
|
E3L034958
BDB034958
|
US20240368153, Example 1-3
Cc1cc(N)nc2cc(-c3cccnc3)cnc12
|
C14H12N4 236.278000 |
PJNYMJYHWXXOBJ-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703885; PubChem:CID167289044
|
Local ready
Direct docking supported
|
|
E3L034959
BDB034959
|
US20240368153, Example 1-4
Cc1cc(N)nc2cc(-c3cccnn3)cnc12
|
C13H11N5 237.266000 |
HXIPASNYKUHCAT-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703886; PubChem:CID172487064
|
Local ready
Direct docking supported
|
|
E3L034960
BDB034960
|
US20240368153, Example 1-5
Cc1cc(N)nc2cc(-c3ccsn3)cnc12
|
C12H10N4S 242.307000 |
ILRUNGHBIYFCTN-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703887; PubChem:CID166460453
|
Local ready
Direct docking supported
|