| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L003981
BDB003981
|
US20250388593, Example 213
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(CCC(=O)OC(C)(C)C)c21
|
C21H27N3O5 401.463000 |
YFMYPKWDAAKLOK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88640; PubChem:CID171844166
|
Local ready
Direct docking supported
|
|
E3L003982
BDB003982
|
US20250388593, Example 214
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(CCCCC(=O)OC(C)(C)C)c21
|
C23H31N3O5 429.517000 |
DSMLRTCVSBPJTE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88641; PubChem:CID175638720
|
Local ready
Direct docking supported
|
|
E3L003983
BDB003983
|
US20250388593, Example 215
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C#CCCCCCC(=O)OC(C)(C)C)cc21
|
C26H33N3O5 467.566000 |
PATVSAKEELVHBO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88642; PubChem:CID175638724
|
Local ready
Direct docking supported
|
|
E3L003984
BDB003984
|
US20250388593, Example 216
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(CCCCCCCC(=O)OC(C)(C)C)cc21
|
C26H37N3O5 471.598000 |
AWUXGNWQMCKSFH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88643; PubChem:CID175638725
|
Local ready
Direct docking supported
|
|
E3L003985
BDB003985
|
US20250388593, Example 217
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(CCCCC(=O)OC(C)(C)C)cc21
|
C23H31N3O5 429.517000 |
ILXVOACYTGKRNW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88644; PubChem:CID175638726
|
Local ready
Direct docking supported
|
|
E3L003986
BDB003986
|
US20250388593, Example 218
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc21
|
C24H32N4O5 456.543000 |
TUGYNVKDXZIADZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88645; PubChem:CID171844091
|
Local ready
Direct docking supported
|
|
E3L003987
BDB003987
|
US20250388593, Example 219
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C3CCN(CC(=O)OC(C)(C)C)CC3)cc21
|
C25H34N4O5 470.570000 |
OJQDZJWQQFRSRX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88646; PubChem:CID171844054
|
Local ready
Direct docking supported
|
|
E3L003988
BDB003988
|
US20250388593, Example 220
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(C3=CCN(C(=O)OC(C)(C)C)CC3)c21
|
C24H30N4O5 454.527000 |
BSYPHYPDQCQAGM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88682; PubChem:CID171844116
|
Local ready
Direct docking supported
|
|
E3L003989
BDB003989
|
BDBM89212
[C]Oc1cc([C][C]c2ccccc2)c(C([O])=O)c([O])c1[C]/[C]=C(/[C])[C][C][C]=C([C])[C]
|
C26H6O4 382.330000 |
AOFZKACZCBVRHL-UHFFFAOYSA-N | P37231 | Peroxisome proliferator-activated receptor gamma |
BindingDB
BindingDB:BDBM89212
|
Local ready
Direct docking supported
|
|
E3L003990
BDB003990
|
1-(3,4-Dichlorobenzyl)-4,6-dimethyl-isatin
Cc1cc(C)c2c(c1)N(Cc1ccc(Cl)c(Cl)c1)C(=O)C2=O
|
C17H13Cl2NO2 334.202000 |
YLTIMTDAACDJAV-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89226; PubChem:CID53389328
|
Local ready
Direct docking supported
|
|
E3L003991
BDB003991
|
6-Chloro-1-(3,4-dichlorobenzyl)isatin
O=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2cc(Cl)ccc21
|
C15H8Cl3NO2 340.593000 |
MOYGLYKQDFJZQO-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89227; PubChem:CID53389327
|
Local ready
Direct docking supported
|
|
E3L003992
BDB003992
|
BDBM89489
Cc1nn(CC(C)C(=O)O)c(C)c1Br
|
C9H13BrN2O2 261.119000 |
BZLIXBYMKOSUCJ-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89489; PubChem:CID6457554
|
Local ready
Direct docking supported
|
|
E3L003993
BDB003993
|
3-(3,5-Dimethyl-1-pyrazolyl)-2-methylbutanoic acid
Cc1cc(C)n(C(C)C(C)C(=O)O)n1
|
C10H16N2O2 196.250000 |
PUWWRVCWHZQCNL-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89490; PubChem:CID45596943
|
Local ready
Direct docking supported
|
|
E3L003994
BDB003994
|
2-methyl-3-(1H-pyrazol-1-yl)propanoic acid
CC(Cn1cccn1)C(=O)O
|
C7H10N2O2 154.169000 |
FWIFKSTVTRTEQU-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89491; PubChem:CID6483897
|
Local ready
Direct docking supported
|
|
E3L003995
BDB003995
|
BDBM89492
COc1cc(OC)c(C2=NOC(C(=O)O)C2)cc1Cl
|
C12H12ClNO5 285.683000 |
IDRVXUULWFWTEI-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89492; PubChem:CID2974597
|
Local ready
Direct docking supported
|
|
E3L003996
BDB003996
|
BDBM89493
O=C(O)C1CC(c2ccccc2O)=NO1
|
C10H9NO4 207.185000 |
FRDPLMQZUFGNIK-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89493; PubChem:CID2962281
|
Local ready
Direct docking supported
|
|
E3L003997
BDB003997
|
BDBM89494
O=C(O)C1CC(c2ccccc2Cl)=NO1
|
C10H8ClNO3 225.631000 |
XBABASIBBODKAE-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89494; PubChem:CID2962259
|
Local ready
Direct docking supported
|
|
E3L003998
BDB003998
|
BDBM89495
O=C(O)C1CC(c2cccc(Br)c2)=NO1
|
C10H8BrNO3 270.082000 |
PPLKIMIGZSEKTE-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89495; PubChem:CID2962252
|
Local ready
Direct docking supported
|
|
E3L003999
BDB003999
|
BDBM89496
O=C(O)C1CC(c2c(F)cccc2Cl)=NO1
|
C10H7ClFNO3 243.621000 |
KIWWDOKNJZYHSY-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89496; PubChem:CID2962193
|
Local ready
Direct docking supported
|
|
E3L004000
BDB004000
|
BDBM89497
COc1ccc(OC)c(C2=NOC(C(=O)O)C2)c1
|
C12H13NO5 251.238000 |
TVKIPMFFMHSWBP-UHFFFAOYSA-N | O14727 | Apoptotic protease-activating factor 1 |
BindingDB, PubChem
BindingDB:BDBM89497; PubChem:CID25220803
|
Local ready
Direct docking supported
|