| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L003961
BDB003961
|
US20250388593, Example 188
COc1ccc2sc(N3CCC4(CCCC(=O)NC4=O)C3)nc2c1
|
C17H19N3O3S 345.424000 |
FTXBZZGJMZYDPX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88620; PubChem:CID175638827
|
Local ready
Direct docking supported
|
|
E3L003962
BDB003962
|
US20250388593, Example 189
COc1cccc2sc(N3CCC4(CCCC(=O)NC4=O)C3)nc12
|
C17H19N3O3S 345.424000 |
ADQAQIADMURXSX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88621; PubChem:CID177778484
|
Local ready
Direct docking supported
|
|
E3L003963
BDB003963
|
US20250388593, Example 190
CC(C)(C)OC(=O)N1CCc2c(ncnc2N2CCC3(CCCC(=O)NC3=O)C2)C1
|
C21H29N5O4 415.494000 |
NWKFMOURUWMWBD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88622; PubChem:CID175638829
|
Local ready
Direct docking supported
|
|
E3L003964
BDB003964
|
US20250388593, Example 149
CC(C)(C)OC(=O)COc1ccccc1-c1cn(C2CCCC(=O)NC2=O)nn1
|
C20H24N4O5 400.435000 |
VEQCCCXPTJKADU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88623; PubChem:CID171844060
|
Local ready
Direct docking supported
|
|
E3L003965
BDB003965
|
US20250388593, Example 192
COc1ccc(C#N)c(N2CCC3(CCCC(=O)NC3=O)C2)c1
|
C17H19N3O3 313.357000 |
GDUAVMBMCPGAQU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88624; PubChem:CID178289691
|
Local ready
Direct docking supported
|
|
E3L003966
BDB003966
|
US20250388593, Example 193
CC(C)(C)OC(=O)COc1ccc(C#N)c(N2CCC3(CCCC(=O)NC3=O)C2)c1
|
C22H27N3O5 413.474000 |
DVQKNFCCPYVUDL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88625; PubChem:CID177778588
|
Local ready
Direct docking supported
|
|
E3L003967
BDB003967
|
US20250388593, Example 194
CC(C)(C)OC(=O)CCCCCCCCCOc1ccc(C#N)c(N2CCC3(CCCC(=O)NC3=O)C2)c1
|
C30H43N3O5 525.690000 |
AHEPBFHELXHSDI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88626; PubChem:CID178289692
|
Local ready
Direct docking supported
|
|
E3L003968
BDB003968
|
US20250388593, Example 195
CC(C)(C)OC(=O)CCCCCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21
|
C25H35N3O5 457.571000 |
RVHQTWFOORQKIY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88627; PubChem:CID175638675
|
Local ready
Direct docking supported
|
|
E3L003969
BDB003969
|
US20250388593, Example 196
CC(C)(C)OC(=O)NCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21
|
C21H28N4O5 416.478000 |
KLPCWRGHWFJFFD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88628; PubChem:CID171844121
|
Local ready
Direct docking supported
|
|
E3L003970
BDB003970
|
US20250388593, Example 197
CC(C)(C)OC(=O)NCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21
|
C20H26N4O5 402.451000 |
JDLCLGLNJIICNC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88629; PubChem:CID171843940
|
Local ready
Direct docking supported
|
|
E3L003971
BDB003971
|
US20250388593, Example 198
CC(C)(C)OC(=O)NCCCCCCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21
|
C25H36N4O5 472.586000 |
UDSKZJIPLUMMOQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88630; PubChem:CID177778501
|
Local ready
Direct docking supported
|
|
E3L003972
BDB003972
|
US20250388593, Example 199
CC(C)(C)OC(=O)NCCOCCOCCn1c(=O)n(C2CCCC(=O)NC2=O)c2ccccc21
|
C24H34N4O7 490.557000 |
QNBHRKZGWGPJEU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88631; PubChem:CID171844167
|
Local ready
Direct docking supported
|
|
E3L003973
BDB003973
|
3-(2-Oxoazepan-3-yl)-1H-imidazo[4,5-b]pyridin-2-one
O=C1NCCCCC1N1C(=O)NC2CC=CN=C21
|
C12H16N4O2 248.286000 |
JKBMBCWPSBVPJZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88632; PubChem:CID178289693
|
Local ready
Direct docking supported
|
|
E3L003974
BDB003974
|
US20250388593, Example 202
Cc1ccc(NC(=O)NCCCn2c(=O)n(C3CCCC(=O)NC3=O)c3ccccc32)cc1Cl
|
C24H26ClN5O4 483.956000 |
ZHMREHCWAHCJMK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88633; PubChem:CID171843932
|
Local ready
Direct docking supported
|
|
E3L003975
BDB003975
|
US20250388593, Example 203
Cc1cc(NC(=O)NCCn2c(=O)n(C3CCCC(=O)NC3=O)c3ccccc32)ccc1Cl
|
C23H24ClN5O4 469.929000 |
UZRWHBWJPOPJLN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88634; PubChem:CID178289694
|
Local ready
Direct docking supported
|
|
E3L003976
BDB003976
|
US20250388593, Example 206
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(C#CCCCCCC(=O)OC(C)(C)C)c21
|
C26H33N3O5 467.566000 |
FMPBXMHJXLIWJM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88635; PubChem:CID175638697
|
Local ready
Direct docking supported
|
|
E3L003977
BDB003977
|
US20250388593, Example 207
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(CCCCCCCC(=O)OC(C)(C)C)c21
|
C26H37N3O5 471.598000 |
GMMREYYISVKAKQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88636; PubChem:CID175638701
|
Local ready
Direct docking supported
|
|
E3L003978
BDB003978
|
US20250388593, Example 209
O=C(O)CCCCCCCc1nn(C2CCCC(=O)NC2=O)c2ccccc12
|
C21H27N3O4 385.464000 |
WELWTLFSJDLNKE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88637; PubChem:CID175638709
|
Local ready
Direct docking supported
|
|
E3L003979
BDB003979
|
US20250388593, Example 210
Cn1c(=O)n(C2CCCC(=O)NC2=O)c2cccc(I)c21
|
C14H14IN3O3 399.188000 |
UVRIXAXPLOQUCH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88638; PubChem:CID171844158
|
Local ready
Direct docking supported
|
|
E3L003980
BDB003980
|
US20250388593, Example 211
Cn1c(=O)n([C@@H]2CCCC(=O)NC2=O)c2cccc(I)c21
|
C14H14IN3O3 399.188000 |
UVRIXAXPLOQUCH-SNVBAGLBSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88639; PubChem:CID178289695
|
Local ready
Direct docking supported
|