| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041141
BDB041141
|
US20250289799, Example 102
COc1cc(-n2nc(C(F)(F)F)cc2C)ccc1CNc1nc(-c2c(OC)ncnc2C2CC2)ncc1OC
|
C26H26F3N7O3 541.534000 |
RJTZBJCDTKGMAY-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771942; PubChem:CID176244226
|
Local ready
Direct docking supported
|
|
E3L041142
BDB041142
|
US20250289799, Example 103
COc1cc(CNc2nc(-c3c(OC)ncnc3C3CC3)ncc2OC)ccc1-n1nc(C(F)(F)F)cc1C
|
C26H26F3N7O3 541.534000 |
IPVDORQQWAIUQG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771943; PubChem:CID176244207
|
Local ready
Direct docking supported
|
|
E3L041143
BDB041143
|
US20250289799, Example 104
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCC12CCC(c3nc(C(F)(F)F)cn3C)(CC1)CC2
|
C27H32F3N7O2 543.594000 |
LSCYMXIDVNDUBJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771944; PubChem:CID176204081
|
Local ready
Direct docking supported
|
|
E3L041144
BDB041144
|
US20250289799, Example 105
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nc(C)cn2C(F)F)cc1
|
C25H25F2N7O2 493.518000 |
MWUDBUWRDSAWDC-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771945; PubChem:CID176244214
|
Local ready
Direct docking supported
|
|
E3L041145
BDB041145
|
US20250289799, Example 106
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C(C)C)cc1
|
C27H28F3N7O2 539.562000 |
KKUCWXUWJXNTIA-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771946; PubChem:CID176244277
|
Local ready
Direct docking supported
|
|
E3L041146
BDB041146
|
US20250289799, Example 107
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2CF)cc1
|
C25H23F4N7O2 529.498000 |
MHSGMBAFEOIWLI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771947; PubChem:CID176244237
|
Local ready
Direct docking supported
|
|
E3L041147
BDB041147
|
US20250289799, Example 108
COc1ncnc(C2CC2)c1-c1ncc(OC(C)C)c(N(C)CC2CCN(c3nc(C(F)(F)F)cn3C)CC2)n1
|
C27H35F3N8O2 560.625000 |
DBOZFENGGBJQLK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771948; PubChem:CID176244239
|
Local ready
Direct docking supported
|
|
E3L041148
BDB041148
|
US20250289799, Example 109
COc1ncnc(C2CC2)c1-c1ncc(OC(C)C)c(N(C)Cc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C28H30F3N7O2 553.589000 |
JYQZRIVVQIQSGP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771949; PubChem:CID176244113
|
Local ready
Direct docking supported
|
|
E3L041149
BDB041149
|
US20250289799, Example 110
COc1ncnc(C2CC2)c1-c1ncc(OC(C)C)c(NCC2CCN(c3nc(C(F)(F)F)cn3C)CC2)n1
|
C26H33F3N8O2 546.598000 |
DATGSWRZPTVCNE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771950; PubChem:CID176244131
|
Local ready
Direct docking supported
|
|
E3L041150
BDB041150
|
US20250289799, Example 111
COc1ncnc(C2CC2)c1-c1ncc(OC(C)C)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C27H28F3N7O2 539.562000 |
OJUYGOLJAAJENA-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771951; PubChem:CID176244121
|
Local ready
Direct docking supported
|
|
E3L041151
BDB041151
|
US20250289799, Example 112
COc1ncnc(C2CC2)c1-c1ncc(OC(C)C)c(NCC23CCC(c4ccc(C(F)(F)F)cn4)(CC2)CC3)n1
|
C30H35F3N6O2 568.644000 |
MLSCZANKHKJCPG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771952; PubChem:CID176244222
|
Local ready
Direct docking supported
|
|
E3L041152
BDB041152
|
US20250289799, Example 113
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)s2)c2occc2n1
|
C24H20F3N7O2S 527.532000 |
WUGDZUORGPRJJQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771953; PubChem:CID176244155
|
Local ready
Direct docking supported
|
|
E3L041153
BDB041153
|
US20250289799, Example 114
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc3c(c2)CCN(C)C3=O)c2occc2n1
|
C25H24N6O3 456.506000 |
JHRNEWUUWZFTQR-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771954; PubChem:CID176244202
|
Local ready
Direct docking supported
|
|
E3L041154
BDB041154
|
US20250289799, Example 115
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc3c(c2)CCN(C(C)C)C3=O)c2occc2n1
|
C27H28N6O3 484.560000 |
MKERFPVPHAOGED-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771955; PubChem:CID176244197
|
Local ready
Direct docking supported
|
|
E3L041155
BDB041155
|
US20250289799, Example 116
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(OCc3ccccn3)cc2)c2occc2n1
|
C27H24N6O3 480.528000 |
AXSSSLHNJMJVCE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771956; PubChem:CID176244224
|
Local ready
Direct docking supported
|
|
E3L041156
BDB041156
|
US20250289799, Example 117
CCOCCOc1ccc(CNc2nc(-c3c(OC)ncnc3C3CC3)nc3ccoc23)cc1
|
C25H27N5O4 461.522000 |
RAMRMSZVAYAODD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771957; PubChem:CID176244178
|
Local ready
Direct docking supported
|
|
E3L041157
BDB041157
|
US20250289799, Example 118
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(OC3CC(OC)C3)cc2)c2occc2n1
|
C26H27N5O4 473.533000 |
IMKYFMPRYPPYIN-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771958; PubChem:CID176244184
|
Local ready
Direct docking supported
|
|
E3L041158
BDB041158
|
US20250289799, Example 119
COc1cc(-c2nc(C(F)(F)F)cn2C)ccc1CNc1nc(-c2c(OC)ncnc2C2CC2)nc2ccoc12
|
C27H24F3N7O3 551.529000 |
WKOOZXNBACCQKW-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771959; PubChem:CID176244148
|
Local ready
Direct docking supported
|
|
E3L041159
BDB041159
|
US20250289799, Example 120
COc1cc(CNc2nc(-c3c(OC)ncnc3C3CC3)nc3ccoc23)ccc1-c1nc(C(F)(F)F)cn1C
|
C27H24F3N7O3 551.529000 |
ZTNYEZZUKQDTAD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771960; PubChem:CID176244274
|
Local ready
Direct docking supported
|
|
E3L041160
BDB041160
|
US20250289799, Example 121
COc1cc(-n2nc(C(F)(F)F)cc2C)ccc1CNc1nc(-c2c(OC)ncnc2C2CC2)nc2ccoc12
|
C27H24F3N7O3 551.529000 |
MPGOOXPXORLUDP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771961; PubChem:CID176244138
|
Local ready
Direct docking supported
|