| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041121
BDB041121
|
US20250289799, Example 82
COc1cc(CNc2nc(-c3ccccc3C(C)C)nc3ccoc23)ccc1-c1nc(C(F)(F)F)cn1C
|
C28H26F3N5O2 521.543000 |
LVYZQLKHUFVKJA-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771922; PubChem:CID176244229
|
Local ready
Direct docking supported
|
|
E3L041122
BDB041122
|
US20250289799, Example 83
COc1cc(-n2nc(C(F)(F)F)cc2C)ccc1CNc1nc(-c2ccccc2C(C)C)nc2ccoc12
|
C28H26F3N5O2 521.543000 |
QZQRPSWKVFRMAR-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771923; PubChem:CID176244286
|
Local ready
Direct docking supported
|
|
E3L041123
BDB041123
|
US20250289799, Example 84
COc1cc(CNc2nc(-c3ccccc3C(C)C)nc3ccoc23)ccc1-n1nc(C(F)(F)F)cc1C
|
C28H26F3N5O2 521.543000 |
SIOQUJKMCMRGKJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771924; PubChem:CID176244153
|
Local ready
Direct docking supported
|
|
E3L041124
BDB041124
|
US20250289799, Example 85
C#Cc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C27H24F3N5 475.518000 |
MLSWUXJGLQVYPB-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771925; PubChem:CID176244116
|
Local ready
Direct docking supported
|
|
E3L041125
BDB041125
|
US20250289799, Example 86
CC(C)c1ccccc1-c1ncc(OC(F)F)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C26H24F5N5O 517.502000 |
MDNLSVZCADUZRA-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771926; PubChem:CID176244140
|
Local ready
Direct docking supported
|
|
E3L041126
BDB041126
|
US20250289799, Example 87
CC(C)c1ccccc1-c1ncc(N2CCOCC2)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C29H31F3N6O 536.602000 |
GFRSKJKFRWTEFP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771927; PubChem:CID176244304
|
Local ready
Direct docking supported
|
|
E3L041127
BDB041127
|
US20250289799, Example 88
CC(C)c1ccccc1-c1ncc(N2CCN(C)CC2)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C30H34F3N7 549.645000 |
ADVIRJZRMRVCGM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771928; PubChem:CID176244223
|
Local ready
Direct docking supported
|
|
E3L041128
BDB041128
|
US20250289799, Example 89
CC(C)c1ccccc1-c1ncc(O)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C25H24F3N5O 467.495000 |
YDBALLYLPVOBKL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771929; PubChem:CID165406174
|
Local ready
Direct docking supported
|
|
E3L041129
BDB041129
|
US20250289799, Example 89
CC(C)c1ccccc1-c1ncc(O)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C25H24F3N5O 467.495000 |
YDBALLYLPVOBKL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771930; PubChem:CID165406174
|
Local ready
Direct docking supported
|
|
E3L041130
BDB041130
|
US20250289799, Example 91
COC(=O)Cc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C28H28F3N5O2 523.559000 |
PVMJYWNDGDXJAE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771931; PubChem:CID176244172
|
Local ready
Direct docking supported
|
|
E3L041131
BDB041131
|
US20250289799, Example 92
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(C)CC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C25H31F3N8O2 532.571000 |
LXNVEIWSRUSHHU-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771932; PubChem:CID176244094
|
Local ready
Direct docking supported
|
|
E3L041132
BDB041132
|
US20250289799, Example 93
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C(C)C)cc1
|
C28H30F3N7O2 553.589000 |
XHARODXCKIWDRS-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771933; PubChem:CID176244132
|
Local ready
Direct docking supported
|
|
E3L041133
BDB041133
|
US20250289799, Example 94
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2ccccn2)cc1
|
C25H24N6O2 440.507000 |
AYJAZCDTLQXCIM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771934; PubChem:CID176244086
|
Local ready
Direct docking supported
|
|
E3L041134
BDB041134
|
US20250289799, Example 95
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C24H29F3N8O2 518.544000 |
AQGJCMOJKXVHOM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771935; PubChem:CID176244174
|
Local ready
Direct docking supported
|
|
E3L041135
BDB041135
|
US20250289799, Example 29
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H24F3N7O2 511.508000 |
GUVUYALCVUAQLY-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771936; PubChem:CID176244111
|
Local ready
Direct docking supported
|
|
E3L041136
BDB041136
|
US20250289799, Example 97
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc2c(c1)CCN(C(C)C)C2=O
|
C26H30N6O3 474.565000 |
CXZSWVMSSIIGEW-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771937; PubChem:CID176244230
|
Local ready
Direct docking supported
|
|
E3L041137
BDB041137
|
US20250289799, Example 98
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(OCc2ccccn2)cc1
|
C26H26N6O3 470.533000 |
MBZOEDFQWZTTGX-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771938; PubChem:CID176244295
|
Local ready
Direct docking supported
|
|
E3L041138
BDB041138
|
US20250289799, Example 99
CCOCCOc1ccc(CNc2nc(-c3c(OC)ncnc3C3CC3)ncc2OC)cc1
|
C24H29N5O4 451.527000 |
YEFXKMIUOCCOSN-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771939; PubChem:CID176244195
|
Local ready
Direct docking supported
|
|
E3L041139
BDB041139
|
US20250289799, Example 100
COc1cc(-c2nc(C(F)(F)F)cn2C)ccc1CNc1nc(-c2c(OC)ncnc2C2CC2)ncc1OC
|
C26H26F3N7O3 541.534000 |
RTBGYULEUIBEGG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771940; PubChem:CID176244247
|
Local ready
Direct docking supported
|
|
E3L041140
BDB041140
|
US20250289799, Example 101
COc1cc(CNc2nc(-c3c(OC)ncnc3C3CC3)ncc2OC)ccc1-c1nc(C(F)(F)F)cn1C
|
C26H26F3N7O3 541.534000 |
DZLBSNGAHUWGOT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771941; PubChem:CID176244233
|
Local ready
Direct docking supported
|