| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041221
BDB041221
|
US20250289799, Example 182
COc1cnn(C(C)C)c1-c1nc(NCc2ccc(-n3nc(C(F)(F)F)cc3C)cc2)c2occc2n1
|
C25H24F3N7O2 511.508000 |
GXVWXLQYZCEQPF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772022; PubChem:CID176244152
|
Local ready
Direct docking supported
|
|
E3L041222
BDB041222
|
US20250289799, Example 183
COc1cnc(-c2c(OC)cnn2C2CC2)nc1NCc1ccc(-c2ccccn2)cc1
|
C24H24N6O2 428.496000 |
GYUIOLMCFNFNFT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772023; PubChem:CID176244115
|
Local ready
Direct docking supported
|
|
E3L041223
BDB041223
|
US20250289799, Example 184
COc1cnc(-c2c(OC)cnn2C2CC2)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C23H29F3N8O2 506.533000 |
CUNCAMDYXWQYPS-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772024; PubChem:CID176244179
|
Local ready
Direct docking supported
|
|
E3L041224
BDB041224
|
US20250289799, Example 185
COc1cnn(C2CC2)c1-c1ncc(OC(F)F)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C24H22F5N7O2 535.477000 |
WWILVHUNGUWQNS-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772025; PubChem:CID176244096
|
Local ready
Direct docking supported
|
|
E3L041225
BDB041225
|
US20250289799, Example 186
COc1cnc(-c2c(C)noc2C(C)C)nc1N(C)CC1CCN(c2ccccn2)CC1
|
C24H32N6O2 436.560000 |
AFQXCUPMKLEOBQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772026; PubChem:CID176244212
|
Local ready
Direct docking supported
|
|
E3L041226
BDB041226
|
US20250289799, Example 187
COc1cnc(-c2c(C)noc2C(C)C)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C23H30F3N7O2 493.534000 |
YOIYORLJLANVFO-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772027; PubChem:CID176244095
|
Local ready
Direct docking supported
|
|
E3L041227
BDB041227
|
US20250289799, Example 188
COc1cnc(-c2c(C)noc2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C24H25F3N6O2 486.498000 |
MKYIVUPNUCEBHB-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772028; PubChem:CID176244306
|
Local ready
Direct docking supported
|
|
E3L041228
BDB041228
|
US20250289799, Example 189
Cc1noc(C(C)C)c1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2occc2n1
|
C25H23N5O2 425.492000 |
XSASQTJEEZBMKG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772029; PubChem:CID176244305
|
Local ready
Direct docking supported
|
|
E3L041229
BDB041229
|
US20250289799, Example 190
Cc1noc(C(C)C)c1-c1ncc(OC(F)F)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C24H23F5N6O2 522.478000 |
HJKPOIKPRMLBRL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772030; PubChem:CID176244091
|
Local ready
Direct docking supported
|
|
E3L041230
BDB041230
|
US20250289799, Example 191
COc1cnc(-c2c(Cl)cnn2C2CC2)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C24H23ClF3N7O 517.943000 |
CQGAVWVWPIWIHI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772031; PubChem:CID176244149
|
Local ready
Direct docking supported
|
|
E3L041231
BDB041231
|
US20250289799, Example 192
COc1cnc(-c2c(Cl)cnn2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C23H21ClF3N7O 503.916000 |
GSRMRBRECUZMKQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772032; PubChem:CID176244122
|
Local ready
Direct docking supported
|
|
E3L041232
BDB041232
|
US20250289799, Example 193
COc1cnc(-c2cncnc2C2CC2)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H24F3N7O 495.509000 |
DRWFBECKFLLUKD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772033; PubChem:CID176244176
|
Local ready
Direct docking supported
|
|
E3L041233
BDB041233
|
US20250289799, Example 194
COc1cnc(-c2cncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C24H22F3N7O 481.482000 |
DSICGXYPFVXBCT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772034; PubChem:CID176244199
|
Local ready
Direct docking supported
|
|
E3L041234
BDB041234
|
US20250289799, Example 195
COc1cnc(-c2cncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)F)cn2C)cc1
|
C24H23F2N7O 463.492000 |
SFOUOIDIEVEZOD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772035; PubChem:CID176244133
|
Local ready
Direct docking supported
|
|
E3L041235
BDB041235
|
US20250289799, Example 196
Cn1cc(C(F)(F)F)nc1-c1ccc(CNc2nc(-c3cncnc3C3CC3)nc3ccoc23)cc1
|
C25H20F3N7O 491.477000 |
OANXJARSNGGWRE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772036; PubChem:CID176244285
|
Local ready
Direct docking supported
|
|
E3L041236
BDB041236
|
US20250289799, Example 197
Cn1cc(C(F)F)nc1-c1ccc(CNc2nc(-c3cncnc3C3CC3)nc3ccoc23)cc1
|
C25H21F2N7O 473.487000 |
PBXDIBDNQSSAHW-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772037; PubChem:CID176244241
|
Local ready
Direct docking supported
|
|
E3L041237
BDB041237
|
US20250289799, Example 198
COc1cnc(-c2c(C)cnn2C2CC2)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H26F3N7O 497.525000 |
TWSHPWAFQSQPPQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772038; PubChem:CID176244228
|
Local ready
Direct docking supported
|
|
E3L041238
BDB041238
|
US20250289799, Example 199
COc1cnc(-c2c(C)cnn2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C24H24F3N7O 483.498000 |
BDHZVONZIFUFFZ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772039; PubChem:CID176244180
|
Local ready
Direct docking supported
|
|
E3L041239
BDB041239
|
US20250289799, Example 200
COc1cnc(-c2c(C)cnn2C(C)C)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H28F3N7O 499.541000 |
GQYFENFXGKYSDT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772040; PubChem:CID176244198
|
Local ready
Direct docking supported
|
|
E3L041240
BDB041240
|
US20250289799, Example 201
COc1cnc(-c2c(C)cnn2C(C)C)nc1N(C)Cc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C25H28F3N7O 499.541000 |
DVQIMNZTUPBBPJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772041; PubChem:CID176244205
|
Local ready
Direct docking supported
|