| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041161
BDB041161
|
US20250289799, Example 122
COc1cc(CNc2nc(-c3c(OC)ncnc3C3CC3)nc3ccoc23)ccc1-n1nc(C(F)(F)F)cc1C
|
C27H24F3N7O3 551.529000 |
QWTOQZGMGGGZFB-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771962; PubChem:CID176244211
|
Local ready
Direct docking supported
|
|
E3L041162
BDB041162
|
US20250289799, Example 123
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(-c3nc(C(F)F)cn3C)cc2)c2occc2n1
|
C26H23F2N7O2 503.513000 |
IRVYRMKTHVFEON-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771963; PubChem:CID176244175
|
Local ready
Direct docking supported
|
|
E3L041163
BDB041163
|
US20250289799, Example 124
COc1ncnc(C2CC2)c1-c1ncc(Cl)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C24H21ClF3N7O 515.927000 |
BWMYLQMWJXQQFQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771964; PubChem:CID176244296
|
Local ready
Direct docking supported
|
|
E3L041164
BDB041164
|
US20250289799, Example 125
COc1ncnc(C2CC2)c1-c1ncc(Cl)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C3CC3)cc2)n1
|
C26H23ClF3N7O 541.965000 |
IKJHVHWHEHMGQM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771965; PubChem:CID176244217
|
Local ready
Direct docking supported
|
|
E3L041165
BDB041165
|
US20250289799, Example 126
COc1ncnc(C2CC2)c1-c1ncc(Cl)c(NCc2ccc(-c3nc(C(F)(F)F)cn3CF)cc2)n1
|
C24H20ClF4N7O 533.917000 |
PXGWTYOBZBPUTA-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771966; PubChem:CID176244260
|
Local ready
Direct docking supported
|
|
E3L041166
BDB041166
|
US20250289799, Example 127
COc1ncnc(C2CC2)c1-c1ncc(F)c(N(C)Cc2ccc(-c3nc(C(F)(F)F)cn3C(C)C)cc2)n1
|
C27H27F4N7O 541.553000 |
NWZBULYWZXMKKP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771967; PubChem:CID176244190
|
Local ready
Direct docking supported
|
|
E3L041167
BDB041167
|
US20250289799, Example 128
[2H]C([2H])([2H])N(Cc1ccc(-c2nc(C(F)(F)F)cn2C2CC2)cc1)c1nc(-c2c(OC)ncnc2C2CC2)ncc1F
|
C27H25F4N7O 542.555305 |
JHSYQHLNUBHKGO-FIBGUPNXSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771968; PubChem:CID176244181
|
Local ready
Direct docking supported
|
|
E3L041168
BDB041168
|
US20250289799, Example 129
[2H]C([2H])([2H])N(Cc1ccc(-c2nc(C(F)(F)F)cn2C(C)C)cc1)c1nc(-c2c(OC)ncnc2C2CC2)ncc1F
|
C27H27F4N7O 544.571305 |
NWZBULYWZXMKKP-HPRDVNIFSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771969; PubChem:CID176244186
|
Local ready
Direct docking supported
|
|
E3L041169
BDB041169
|
US20250289799, Example 130
[2H]C([2H])([2H])N(Cc1ccc(-c2nc(C(F)(F)F)cn2CF)cc1)c1nc(-c2c(OC)ncnc2C2CC2)ncc1F
|
C25H22F5N7O 534.507305 |
AZRNVXAZPIAHOO-FIBGUPNXSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771970; PubChem:CID176244193
|
Local ready
Direct docking supported
|
|
E3L041170
BDB041170
|
US20250289799, Example 131
COc1ncnc(C2CC2)c1-c1ncc(C#N)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C25H21F3N8O 506.492000 |
JMEDKCLMXAJDMF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771971; PubChem:CID165400951
|
Local ready
Direct docking supported
|
|
E3L041171
BDB041171
|
US20250289799, Example 132
C#Cc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C26H22F3N7O 505.504000 |
SIECUWPKUMGQKK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771972; PubChem:CID176244123
|
Local ready
Direct docking supported
|
|
E3L041172
BDB041172
|
US20250289799, Example 133
COc1ncnc(C2CC2)c1-c1ncc(OC(F)F)c(NCC2CCN(c3nc(C(F)(F)F)cn3C)CC2)n1
|
C24H27F5N8O2 554.524000 |
ULNPAWMBAVXQEI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771973; PubChem:CID176244298
|
Local ready
Direct docking supported
|
|
E3L041173
BDB041173
|
US20250289799, Example 134
COc1ncnc(C2CC2)c1-c1ncc(OC(F)F)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C25H22F5N7O2 547.488000 |
FDJNPANWBIDYFE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771974; PubChem:CID176244110
|
Local ready
Direct docking supported
|
|
E3L041174
BDB041174
|
US20250289799, Example 135
COc1ncnc(C2CC2)c1-c1ncc(OC(F)F)c(NCc2ccc(-n3nc(C(F)(F)F)cc3C)cc2)n1
|
C25H22F5N7O2 547.488000 |
PNCHVEHBGGOBQM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771975; PubChem:CID176244157
|
Local ready
Direct docking supported
|
|
E3L041175
BDB041175
|
US20250289799, Example 136
COc1cc(-c2nc(C(F)(F)F)cn2C)ccc1CNc1nc(-c2c(OC)ncnc2C2CC2)ncc1OC(F)F
|
C26H24F5N7O3 577.514000 |
XROZNNHDQFNGSQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771976; PubChem:CID176244314
|
Local ready
Direct docking supported
|
|
E3L041176
BDB041176
|
US20250289799, Example 137
COc1ncnc(C2CC2)c1-c1ncc(CO)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C(C)C)cc2)n1
|
C27H28F3N7O2 539.562000 |
DCKKLJKTUKGBKK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771977; PubChem:CID170707707
|
Local ready
Direct docking supported
|
|
E3L041177
BDB041177
|
US20250289799, Example 138
COCc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C(C)C)cc1
|
C29H32F3N7O2 567.616000 |
XOKIRIXERRFQJF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771978; PubChem:CID176244204
|
Local ready
Direct docking supported
|
|
E3L041178
BDB041178
|
US20250289799, Example 139
C#CCN(Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1)c1nc(-c2c(OC)ncnc2C2CC2)ncc1OC
|
C28H26F3N7O2 549.557000 |
PBUPMKGKBDYPIJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771979; PubChem:CID176244134
|
Local ready
Direct docking supported
|
|
E3L041179
BDB041179
|
US20250289799, Example 140
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1)C1CCOC1
|
C29H30F3N7O3 581.599000 |
LNHRYZHXNDHHSY-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771980; PubChem:CID176244185
|
Local ready
Direct docking supported
|
|
E3L041180
BDB041180
|
US20250289799, Example 141
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1)C1CC1
|
C28H28F3N7O2 551.573000 |
WOUITGFYYPCTCH-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771981; PubChem:CID176244238
|
Local ready
Direct docking supported
|