| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041181
BDB041181
|
US20250289799, Example 142
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1)OC
|
C26H26F3N7O3 541.534000 |
FXISMXFIIGMYTK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771982; PubChem:CID176244225
|
Local ready
Direct docking supported
|
|
E3L041182
BDB041182
|
US20250289799, Example 143
COc1cnc(-c2cccc3ccn(C)c23)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C26H23F3N6O 492.505000 |
MNAYUBDIGKAJKM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771983; PubChem:CID176244124
|
Local ready
Direct docking supported
|
|
E3L041183
BDB041183
|
US20250289799, Example 144
COc1cnc(-c2cccc3ccn(C)c23)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C26H23F3N6O 492.505000 |
IKIITLCXKANIJG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771984; PubChem:CID176244232
|
Local ready
Direct docking supported
|
|
E3L041184
BDB041184
|
US20250289799, Example 145
COc1cnc(-c2cccc3c2N(C)CC3)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C26H25F3N6O 494.521000 |
JJIDOUKUWMIRAP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771985; PubChem:CID176244220
|
Local ready
Direct docking supported
|
|
E3L041185
BDB041185
|
US20250289799, Example 146
COc1cnc(-c2cccc3c2N(C)CC3)nc1NCc1ccc(-n2ncc(C(F)(F)F)c2C)cc1
|
C26H25F3N6O 494.521000 |
YYCNXLDRQNUZHC-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771986; PubChem:CID176244171
|
Local ready
Direct docking supported
|
|
E3L041186
BDB041186
|
US20250289799, Example 147
COc1cnc(-c2c(C)ncn2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C24H26F3N7O 485.514000 |
HZPAZQBPENZHIE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771987; PubChem:CID176244213
|
Local ready
Direct docking supported
|
|
E3L041187
BDB041187
|
US20250289799, Example 148
COc1cnc(-c2c(C)ncn2C(C)C)nc1NCC12CCC(c3ccc(C(F)(F)F)cn3)(CC1)CC2
|
C27H33F3N6O 514.596000 |
LKZPKIMGGMTVRT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771988; PubChem:CID176244169
|
Local ready
Direct docking supported
|
|
E3L041188
BDB041188
|
US20250289799, Example 149
Cc1ncn(C(C)C)c1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2occc2n1
|
C25H24F3N7O 495.509000 |
LCISFGYYNYGWIJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771989; PubChem:CID176244125
|
Local ready
Direct docking supported
|
|
E3L041189
BDB041189
|
US20250289799, Example 150
Cc1ncn(C(C)C)c1-c1nc(NCC23CCC(c4ccc(C(F)(F)F)cn4)(CC2)CC3)c2occc2n1
|
C28H31F3N6O 524.591000 |
CZHWCACKZIFZER-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771990; PubChem:CID176244161
|
Local ready
Direct docking supported
|
|
E3L041190
BDB041190
|
US20250289799, Example 151
COc1cnc(-c2cccnc2C2CC2)nc1N(C)CC1CCN(c2ccccn2)CC1
|
C25H30N6O 430.556000 |
ZJVUSAMCQGNICK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771991; PubChem:CID176244088
|
Local ready
Direct docking supported
|
|
E3L041191
BDB041191
|
US20250289799, Example 152
COc1cnc(-c2cccnc2C2CC2)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C24H28F3N7O 487.530000 |
ZQNQTDMTXXAHSW-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771992; PubChem:CID176244183
|
Local ready
Direct docking supported
|
|
E3L041192
BDB041192
|
US20250289799, Example 153
COc1cnc(-c2cccnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H23F3N6O 480.494000 |
VEQWYGMKAAYVDQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771993; PubChem:CID176244117
|
Local ready
Direct docking supported
|
|
E3L041193
BDB041193
|
US20250289799, Example 154
COc1cnc(-c2cccnc2C2CC2)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C25H23F3N6O 480.494000 |
GGMRHCFMLKXRKU-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771994; PubChem:CID176244151
|
Local ready
Direct docking supported
|
|
E3L041194
BDB041194
|
US20250289799, Example 155
c1ccc(-c2ccc(CNc3nc(-c4cccnc4C4CC4)nc4ccoc34)cc2)nc1
|
C26H21N5O 419.488000 |
HVDHOLMEVYRFTO-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771995; PubChem:CID176244166
|
Local ready
Direct docking supported
|
|
E3L041195
BDB041195
|
US20250289799, Example 156
Cn1cc(C(F)(F)F)nc1-c1ccc(CNc2nc(-c3cccnc3C3CC3)ncc2OC(F)F)cc1
|
C25H21F5N6O 516.474000 |
UJCBWPQAIMUNAK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771996; PubChem:CID176244163
|
Local ready
Direct docking supported
|
|
E3L041196
BDB041196
|
US20250289799, Example 157
COc1cnc(-c2cccnc2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H25F3N6O 482.510000 |
QEVNKISCFPAYLJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771997; PubChem:CID176244177
|
Local ready
Direct docking supported
|
|
E3L041197
BDB041197
|
US20250289799, Example 158
COc1cnc(-c2cccnc2C(C)C)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C25H25F3N6O 482.510000 |
MFJLVXMEXCLUPN-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771998; PubChem:CID176244236
|
Local ready
Direct docking supported
|
|
E3L041198
BDB041198
|
US20250289799, Example 159
COc1cnc(-c2ccccc2N(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H25F3N6O 482.510000 |
QHVMEMRQOSXCOR-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771999; PubChem:CID176244143
|
Local ready
Direct docking supported
|
|
E3L041199
BDB041199
|
US20250289799, Example 160
COc1cnc(-c2ccccc2N(C)C)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C25H25F3N6O 482.510000 |
WNBNCBHVOIXVLM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772000; PubChem:CID176244245
|
Local ready
Direct docking supported
|
|
E3L041200
BDB041200
|
US20250289799, Example 161
COc1cnc(-c2c(Cl)cnn2C(C)C)nc1N(C)CC1CCN(c2ccccn2)CC1
|
C23H30ClN7O 455.994000 |
RVUOCXJNQZVASB-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772001; PubChem:CID176244167
|
Local ready
Direct docking supported
|