| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041201
BDB041201
|
US20250289799, Example 162
COc1cnc(-c2c(Cl)cnn2C(C)C)nc1NCc1ccc(-c2ccccn2)cc1
|
C23H23ClN6O 434.931000 |
FEKOIYXJHVOYIJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772002; PubChem:CID176244137
|
Local ready
Direct docking supported
|
|
E3L041202
BDB041202
|
US20250289799, Example 163
COc1cnc(-c2c(Cl)cnn2C(C)C)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C22H28ClF3N8O 512.968000 |
LBMZBFNZSIYGTM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772003; PubChem:CID176244141
|
Local ready
Direct docking supported
|
|
E3L041203
BDB041203
|
US20250289799, Example 164
COc1cnc(-c2c(Cl)cnn2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C23H23ClF3N7O 505.932000 |
VTJJLXUHGABRCL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772004; PubChem:CID176244242
|
Local ready
Direct docking supported
|
|
E3L041204
BDB041204
|
US20250289799, Example 165
COc1cnc(-c2c(Cl)cnn2C(C)C)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C23H23ClF3N7O 505.932000 |
ZXFXEWZESNJFHX-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772005; PubChem:CID176244102
|
Local ready
Direct docking supported
|
|
E3L041205
BDB041205
|
US20250289799, Example 166
CC(C)n1ncc(Cl)c1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2occc2n1
|
C24H21ClN6O 444.926000 |
RKHYTOSBSABWAI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772006; PubChem:CID176244218
|
Local ready
Direct docking supported
|
|
E3L041206
BDB041206
|
US20250289799, Example 167
CC(C)n1ncc(Cl)c1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2occc2n1
|
C24H21ClF3N7O 515.927000 |
LSWVZMVHULIPJJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772007; PubChem:CID176244231
|
Local ready
Direct docking supported
|
|
E3L041207
BDB041207
|
US20250289799, Example 168
Cc1cc(C(F)(F)F)nn1-c1ccc(CNc2nc(-c3c(Cl)cnn3C(C)C)nc3ccoc23)cc1
|
C24H21ClF3N7O 515.927000 |
FXJQKAMCKAKBRM-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772008; PubChem:CID176244201
|
Local ready
Direct docking supported
|
|
E3L041208
BDB041208
|
US20250289799, Example 169
COc1cnc(-c2ccccc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C26H24F3N5O 479.506000 |
MTNAHCMPPPIFRC-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772009; PubChem:CID176244127
|
Local ready
Direct docking supported
|
|
E3L041209
BDB041209
|
US20250289799, Example 170
COc1cnc(-c2ccccc2C2CC2)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C26H24F3N5O 479.506000 |
ZJWUIRUOCIUDHP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772010; PubChem:CID176244206
|
Local ready
Direct docking supported
|
|
E3L041210
BDB041210
|
US20250289799, Example 171
COc1cc(-c2nc(C(F)(F)F)cn2C)ccc1CNc1nc(-c2ccccc2C2CC2)ncc1OC
|
C27H26F3N5O2 509.532000 |
VOCRYBKFHUNSRZ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772011; PubChem:CID176244099
|
Local ready
Direct docking supported
|
|
E3L041211
BDB041211
|
US20250289799, Example 172
COc1cc(CNc2nc(-c3ccccc3C3CC3)ncc2OC)ccc1-c1nc(C(F)(F)F)cn1C
|
C27H26F3N5O2 509.532000 |
PKKLYVQGWYEFEU-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772012; PubChem:CID176244249
|
Local ready
Direct docking supported
|
|
E3L041212
BDB041212
|
US20250289799, Example 173
Cn1cc(C(F)(F)F)nc1-c1ccc(CNc2nc(-c3ccccc3C3CC3)nc3ccoc23)cc1
|
C27H22F3N5O 489.501000 |
ZQQHWDAESUUUBG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772013; PubChem:CID176244105
|
Local ready
Direct docking supported
|
|
E3L041213
BDB041213
|
US20250289799, Example 174
Cc1cc(C(F)(F)F)nn1-c1ccc(CNc2nc(-c3ccccc3C3CC3)nc3ccoc23)cc1
|
C27H22F3N5O 489.501000 |
OATPWTPUURDMDS-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772014; PubChem:CID176244109
|
Local ready
Direct docking supported
|
|
E3L041214
BDB041214
|
US20250289799, Example 175
COc1cc(-c2nc(C(F)(F)F)cn2C)ccc1CNc1nc(-c2ccccc2C2CC2)nc2ccoc12
|
C28H24F3N5O2 519.527000 |
XPNPGOQQUGFDRR-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772015; PubChem:CID176244142
|
Local ready
Direct docking supported
|
|
E3L041215
BDB041215
|
US20250289799, Example 176
COc1cc(CNc2nc(-c3ccccc3C3CC3)nc3ccoc23)ccc1-c1nc(C(F)(F)F)cn1C
|
C28H24F3N5O2 519.527000 |
OCKSPIGTROLROW-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772016; PubChem:CID176244098
|
Local ready
Direct docking supported
|
|
E3L041216
BDB041216
|
US20250289799, Example 177
COc1cnc(-c2c(OC)cnn2C(C)C)nc1N(C)CC1CCN(c2ccccn2)CC1
|
C24H33N7O2 451.575000 |
YFZDWXCDZMWQSO-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772017; PubChem:CID176244267
|
Local ready
Direct docking supported
|
|
E3L041217
BDB041217
|
US20250289799, Example 178
COc1cnc(-c2c(OC)cnn2C(C)C)nc1NCc1ccc(-c2ccccn2)cc1
|
C24H26N6O2 430.512000 |
FSUGLILHBBHYAV-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772018; PubChem:CID176244104
|
Local ready
Direct docking supported
|
|
E3L041218
BDB041218
|
US20250289799, Example 179
COc1cnc(-c2c(OC)cnn2C(C)C)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C23H31F3N8O2 508.549000 |
USEJPPVVCFWZCZ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772019; PubChem:CID176244156
|
Local ready
Direct docking supported
|
|
E3L041219
BDB041219
|
US20250289799, Example 180
COc1cnc(-c2c(OC)cnn2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C24H26F3N7O2 501.513000 |
MMGWTGWOEGIBKG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772020; PubChem:CID176244235
|
Local ready
Direct docking supported
|
|
E3L041220
BDB041220
|
US20250289799, Example 181
COc1cnn(C(C)C)c1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2occc2n1
|
C25H24N6O2 440.507000 |
AVACTWYCWOQDLT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM772021; PubChem:CID176244299
|
Local ready
Direct docking supported
|