| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005301
BDB005301
|
BDBM129793
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cncc(Cl)c2)C3=O)c(OC)n1
|
C25H22Cl2N6O3 525.396000 |
GFQXHOAAJQSTAS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129793; PubChem:CID71678944
|
Local ready
Direct docking supported
|
|
E3L005302
BDB005302
|
BDBM129794
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
|
C30H28Cl2N4O3 563.485000 |
HMIBHMWUUQYKKI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129794; PubChem:CID86766902
|
Local ready
Direct docking supported
|
|
E3L005303
BDB005303
|
BDBM129795
COc1cc(C(=O)N(C)C)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
AIWSYEZTZZFXEJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129795; PubChem:CID86766903
|
Local ready
Direct docking supported
|
|
E3L005304
BDB005304
|
BDBM129796
COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H27Cl2N5O3 552.462000 |
XBJHBEQDHSREQB-QHCPKHFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129796; PubChem:CID71678945
|
Local ready
Direct docking supported
|
|
E3L005305
BDB005305
|
BDBM129797
COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H27Cl2N5O3 552.462000 |
XBJHBEQDHSREQB-HSZRJFAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129797; PubChem:CID86766904
|
Local ready
Direct docking supported
|
|
E3L005306
BDB005306
|
BDBM129798
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H25ClN4O2 496.998000 |
NRKWZUWZDDWWOK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129798; PubChem:CID86766905
|
Local ready
Direct docking supported
|
|
E3L005307
BDB005307
|
BDBM129799
Cc1ccc(Cl)cc1N1C(=O)c2nc(-c3ccccc3O)n(C(C)C)c2C1c1ccc(C#N)cc1
|
C28H23ClN4O2 482.971000 |
YGBFHERIAVTGCX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129799; PubChem:CID136351667
|
Local ready
Direct docking supported
|
|
E3L005308
BDB005308
|
BDBM129800
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C27H22ClFN6O3 532.963000 |
IQYWWOVGZNKRNH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129800; PubChem:CID71678096
|
Local ready
Direct docking supported
|
|
E3L005309
BDB005309
|
BDBM129801
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C28H22ClFN4O2 500.961000 |
GWDRXXNKBIDONN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129801; PubChem:CID86766907
|
Local ready
Direct docking supported
|
|
E3L005310
BDB005310
|
BDBM129802
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C31H27ClFN5O3 572.040000 |
AQMACUOUCKKZIZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129802; PubChem:CID86766908
|
Local ready
Direct docking supported
|
|
E3L005311
BDB005311
|
BDBM129803
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C27H22ClFN6O3 532.963000 |
IFLKNRJOFXYALF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129803; PubChem:CID86766909
|
Local ready
Direct docking supported
|
|
E3L005312
BDB005312
|
BDBM129804
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCC(=O)N(C)C1)C2=O
|
C27H29ClN4O3 493.007000 |
OEJMHTJNVDZAGG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129804; PubChem:CID86766910
|
Local ready
Direct docking supported
|
|
E3L005313
BDB005313
|
BDBM129805
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCC(=O)N(C)C2)C3=O)c(OC)n1
|
C26H29ClN6O4 525.009000 |
YRPAOUCIGFSOET-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129805; PubChem:CID71678946
|
Local ready
Direct docking supported
|
|
E3L005314
BDB005314
|
BDBM129806
COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C27H22Cl2FN5O3 554.409000 |
QWFGRHDCFCBDQY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129806; PubChem:CID71679109
|
Local ready
Direct docking supported
|
|
E3L005315
BDB005315
|
BDBM129807
COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H25Cl2N5O3 550.446000 |
PMNNNNBHSRTDBY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129807; PubChem:CID86766911
|
Local ready
Direct docking supported
|
|
E3L005316
BDB005316
|
BDBM129808
COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C28H22ClFN6O3 544.974000 |
JTNRNERLJWWBGB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129808; PubChem:CID86766912
|
Local ready
Direct docking supported
|
|
E3L005317
BDB005317
|
BDBM129809
COc1ncc(-c2nc3c(n2C2CC2)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C26H20Cl2FN5O3 540.382000 |
NWMSKQFIEYHHRO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129809; PubChem:CID86766913
|
Local ready
Direct docking supported
|
|
E3L005318
BDB005318
|
BDBM129810
COc1ccc(CO)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H29Cl2N3O3 550.486000 |
YJTBLUMJJBCGIZ-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129810; PubChem:CID71655944
|
Local ready
Direct docking supported
|
|
E3L005319
BDB005319
|
BDBM129811
COc1ccc(CO)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H29Cl2N3O3 550.486000 |
YJTBLUMJJBCGIZ-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129811; PubChem:CID71679110
|
Local ready
Direct docking supported
|
|
E3L005320
BDB005320
|
BDBM129812
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O
|
C26H29ClN8O2 521.025000 |
OFXGSVRDCAEEFE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129812; PubChem:CID86766914
|
Local ready
Direct docking supported
|