| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005281
BDB005281
|
BDBM129773
COc1nc(NCCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H30Cl2N6O3 581.504000 |
QSLXODIZZRYVSB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129773; PubChem:CID86766886
|
Local ready
Direct docking supported
|
|
E3L005282
BDB005282
|
BDBM129774
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2cccc(Cl)c2F)cc1
|
C26H21ClFN7O2 517.952000 |
QISCNELKGABNFQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129774; PubChem:CID86766887
|
Local ready
Direct docking supported
|
|
E3L005283
BDB005283
|
BDBM129775
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2cccc(Cl)c2F)cc1
|
C27H23ClFN7O2 531.979000 |
FGTJSOCKXSMWEJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129775; PubChem:CID86766888
|
Local ready
Direct docking supported
|
|
E3L005284
BDB005284
|
BDBM129776
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2cccc(Cl)c2F)cc1
|
C28H25ClFN7O2 546.006000 |
NRXLUQOFKXODJO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129776; PubChem:CID86766889
|
Local ready
Direct docking supported
|
|
E3L005285
BDB005285
|
BDBM129777
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2ccc(F)c(Cl)c2)cc1
|
C26H21ClFN7O2 517.952000 |
HKZYTKQFISYGFA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129777; PubChem:CID86766890
|
Local ready
Direct docking supported
|
|
E3L005286
BDB005286
|
BDBM129778
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2ccc(F)c(Cl)c2)cc1
|
C27H23ClFN7O2 531.979000 |
IENITCCKRMMHIT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129778; PubChem:CID86766891
|
Local ready
Direct docking supported
|
|
E3L005287
BDB005287
|
BDBM129779
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2ccc(F)c(Cl)c2)cc1
|
C28H25ClFN7O2 546.006000 |
RYJXGHVVHUWSCN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129779; PubChem:CID86766892
|
Local ready
Direct docking supported
|
|
E3L005288
BDB005288
|
BDBM129780
COc1nc(N2CC(C)(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H30Cl2N6O3 593.515000 |
QZRFCIAUPJFICU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129780; PubChem:CID86766893
|
Local ready
Direct docking supported
|
|
E3L005289
BDB005289
|
BDBM129781
COc1nc(N2CC(C)(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C31H32Cl2N6O3 607.542000 |
QDKRKAFLRSLXHA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM129781
|
Local ready
Direct docking supported
|
|
E3L005290
BDB005290
|
BDBM129782
COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H28Cl2N6O3 579.488000 |
RWJYYWPZAMHPEH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129782; PubChem:CID71678772
|
Local ready
Direct docking supported
|
|
E3L005291
BDB005291
|
BDBM129783
COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H30Cl2N6O3 593.515000 |
BMFNBERSZYIXPW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129783; PubChem:CID86766895
|
Local ready
Direct docking supported
|
|
E3L005292
BDB005292
|
BDBM129784
COc1cc(CN)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H28Cl2N4O2 535.475000 |
MSRGKAGCQFVQIT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129784; PubChem:CID71678773
|
Local ready
Direct docking supported
|
|
E3L005293
BDB005293
|
BDBM129785
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C28H24Cl2FN3O2 524.423000 |
KWTIXCAYTLZJLJ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129785; PubChem:CID71678942
|
Local ready
Direct docking supported
|
|
E3L005294
BDB005294
|
BDBM129786
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1
|
C26H24Cl2N6O4 555.422000 |
KCQKWYOOVWMMJQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129786; PubChem:CID78147001
|
Local ready
Direct docking supported
|
|
E3L005295
BDB005295
|
BDBM129787
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H27Cl2N7O3 568.465000 |
BHSYORLRKZQLHB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129787; PubChem:CID86766896
|
Local ready
Direct docking supported
|
|
E3L005296
BDB005296
|
BDBM129788
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C25H23Cl2N7O3 540.411000 |
GXVYFINVMHGBLE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129788; PubChem:CID86766897
|
Local ready
Direct docking supported
|
|
E3L005297
BDB005297
|
BDBM129789
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C30H29Cl2N5O4 594.499000 |
UJENNFSXRDFNGG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129789; PubChem:CID86766898
|
Local ready
Direct docking supported
|
|
E3L005298
BDB005298
|
BDBM129790
COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C32H29Cl2FN4O4 623.512000 |
DSVHIZQKOOALOF-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM129790; PubChem:CID86766899
|
Local ready
Direct docking supported
|
|
E3L005299
BDB005299
|
BDBM129791
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C30H27Cl2FN4O3 581.475000 |
BXPMSTDGQOHVRY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129791; PubChem:CID86766900
|
Local ready
Direct docking supported
|
|
E3L005300
BDB005300
|
BDBM129792
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccn1)C2=O
|
C27H24Cl2N4O2 507.421000 |
AQZQMISXFNTOHS-UHFFFAOYSA-N | O15151 | Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM129792; PubChem:CID86766901
|
Local ready
Direct docking supported
|