| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005261
BDB005261
|
BDBM129753
COc1ccc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H26Cl2N4O3 537.447000 |
GEULGLPILCKMCV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129753; PubChem:CID86766870
|
Local ready
Direct docking supported
|
|
E3L005262
BDB005262
|
BDBM129754
CCc1nc(OC)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H28Cl2N4O2 535.475000 |
SPHGMLFGVFUINR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129754; PubChem:CID86766871
|
Local ready
Direct docking supported
|
|
E3L005263
BDB005263
|
BDBM129755
CCc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H26Cl2N4O 529.471000 |
WORAYMUWOFHGGE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129755; PubChem:CID86766872
|
Local ready
Direct docking supported
|
|
E3L005264
BDB005264
|
BDBM129756
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C29H30Cl2N6O2 565.505000 |
CEYPFPHDHTZWEL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129756; PubChem:CID71678602
|
Local ready
Direct docking supported
|
|
E3L005265
BDB005265
|
BDBM129757
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C28H28Cl2N6O2 551.478000 |
OVRPOAGFZYTDML-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129757; PubChem:CID86766873
|
Local ready
Direct docking supported
|
|
E3L005266
BDB005266
|
BDBM129758
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C26H24Cl2N6O2 523.424000 |
CYGATABVHKQRES-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129758; PubChem:CID71678603
|
Local ready
Direct docking supported
|
|
E3L005267
BDB005267
|
BDBM129759
COc1nc(N(C)CCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H30Cl2N6O3 581.504000 |
SGQARYWGCYDRAS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129759; PubChem:CID86766874
|
Local ready
Direct docking supported
|
|
E3L005268
BDB005268
|
BDBM129760
COc1nc(NCCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C28H28Cl2N6O3 567.477000 |
TXAXFJFZJYVGBO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129760; PubChem:CID86766875
|
Local ready
Direct docking supported
|
|
E3L005269
BDB005269
|
BDBM129761
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
|
C27H24ClN7O2 513.989000 |
MJVWLQDZDLHULW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129761; PubChem:CID86766876
|
Local ready
Direct docking supported
|
|
E3L005270
BDB005270
|
BDBM129762
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
|
C28H26ClN7O2 528.016000 |
IOHUBRSXDOQTML-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129762; PubChem:CID86766877
|
Local ready
Direct docking supported
|
|
E3L005271
BDB005271
|
BDBM129763
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)ccc2C)cc1
|
C29H28ClN7O2 542.043000 |
SLDHXOHIMFEVPD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129763; PubChem:CID86766878
|
Local ready
Direct docking supported
|
|
E3L005272
BDB005272
|
BDBM129764
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N(C)C)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)cc1
|
C28H27ClN8O3 559.030000 |
BVXRQVJVSOCXMR-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM129764; PubChem:CID86766879
|
Local ready
Direct docking supported
|
|
E3L005273
BDB005273
|
BDBM129765
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(NC)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)cc1
|
C27H25ClN8O3 545.003000 |
AOTTVOYUTCWOFO-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129765; PubChem:CID86766880
|
Local ready
Direct docking supported
|
|
E3L005274
BDB005274
|
BDBM129766
[C-]#[N+]c1ccc(C2c3c(nc(-c4cnc(N)nc4OC)n3C(C)C)C(=O)N2c2cc(Cl)c(=O)n(C)c2)cc1
|
C26H23ClN8O3 530.976000 |
FJLKTGDDKSVKTJ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129766; PubChem:CID86766881
|
Local ready
Direct docking supported
|
|
E3L005275
BDB005275
|
BDBM129767
CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H28Cl2N6O2 551.478000 |
QHOOVIZXRZTMGC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129767; PubChem:CID86766882
|
Local ready
Direct docking supported
|
|
E3L005276
BDB005276
|
BDBM129768
CCc1nc(OC)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H30Cl2N4O2 549.502000 |
LTRXNVZHKWDWQF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129768; PubChem:CID86766883
|
Local ready
Direct docking supported
|
|
E3L005277
BDB005277
|
BDBM129769
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C27H26Cl2N6O2 537.451000 |
XJJMMPRBAOIDAL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129769; PubChem:CID71678769
|
Local ready
Direct docking supported
|
|
E3L005278
BDB005278
|
BDBM129770
CCc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C31H28Cl2N4O 543.498000 |
OQCSDKCPGCNGSE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129770; PubChem:CID71678770
|
Local ready
Direct docking supported
|
|
E3L005279
BDB005279
|
BDBM129771
COc1ncncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C26H23Cl2N5O2 508.409000 |
JVYRQVSXQJWOJR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129771; PubChem:CID86766884
|
Local ready
Direct docking supported
|
|
E3L005280
BDB005280
|
BDBM129772
COc1nc(N(C)CCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H32Cl2N6O3 595.531000 |
WPGXEJMDQHHDTN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM129772
|
Local ready
Direct docking supported
|