| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005341
BDB005341
|
BDBM129835
COc1cnc(N(C)CCO)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H27Cl2FN6O3 585.467000 |
NOWVGTXXMRRIRK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129835; PubChem:CID86766929
|
Local ready
Direct docking supported
|
|
E3L005342
BDB005342
|
BDBM129836
COc1ncc(-c2nc3c(n2C(C)C)C([C@H]2CC[C@H](C)CC2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C28H34ClN5O3 524.065000 |
QIPWRXYWJNYXCT-UWMOKNSSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM129836
|
Local ready
Direct docking supported
|
|
E3L005343
BDB005343
|
BDBM129837
CCOC(=O)C1(c2ccc(Cl)cc2C)c2c(nc(-c3cnc(OC)nc3OC)n2C(C)C)C(=O)N1c1cc(Cl)ccc1C
|
C31H31Cl2N5O5 624.525000 |
XQNRGIAXRIHLJJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM129837
|
Local ready
Direct docking supported
|
|
E3L005344
BDB005344
|
BDBM129838
COc1ncc(-c2nc3c(n2[C@H](C)CO)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H25Cl2N5O4 554.434000 |
YPDNCAWNHQIVIG-JGHKVMFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129838; PubChem:CID86766932
|
Local ready
Direct docking supported
|
|
E3L005345
BDB005345
|
BDBM129839
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(C#N)cc1C)C2=O
|
C27H24ClN7O2 513.989000 |
ICJLNFGTIBHUHH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129839; PubChem:CID71679281
|
Local ready
Direct docking supported
|
|
E3L005346
BDB005346
|
BDBM129840
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(C#N)cc2C)C3=O)c(OC)n1
|
C28H25ClN6O3 529.000000 |
DIZPOBZOWAGISE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129840; PubChem:CID71679282
|
Local ready
Direct docking supported
|
|
E3L005347
BDB005347
|
BDBM129841
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C#N)C3=O)c(OC)n1
|
C27H22Cl2N6O3 549.418000 |
AHWLLVQJHLCKBM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129841; PubChem:CID86766933
|
Local ready
Direct docking supported
|
|
E3L005348
BDB005348
|
BDBM129842
COc1cnc(N(C)CCO)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H30Cl2N6O3 581.504000 |
AMCPMNKHONILSG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129842; PubChem:CID86766934
|
Local ready
Direct docking supported
|
|
E3L005349
BDB005349
|
BDBM129843
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
CHOHEJZMEHHXSJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129843; PubChem:CID89715173
|
Local ready
Direct docking supported
|
|
E3L005350
BDB005350
|
BDBM129844
CNC(=O)N1CCC(N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1
|
C27H32ClN7O4 554.051000 |
KICKGPNYIUHOAY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129844; PubChem:CID86766935
|
Local ready
Direct docking supported
|
|
E3L005351
BDB005351
|
BDBM129845
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C27H24ClN7O4 545.987000 |
ZUOLXONBWFJJSH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129845; PubChem:CID86766936
|
Local ready
Direct docking supported
|
|
E3L005352
BDB005352
|
BDBM129846
COC(=O)N1CCC(N2C(=O)c3nc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1
|
C27H31ClN6O5 555.035000 |
ZKMZCEKCOKVDFD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129846; PubChem:CID86766937
|
Local ready
Direct docking supported
|
|
E3L005353
BDB005353
|
BDBM129847
CNC(=O)Cc1cc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)cn1
|
C29H26Cl2FN5O3 582.463000 |
WEMVEOJZUHPYLK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129847; PubChem:CID86766938
|
Local ready
Direct docking supported
|
|
E3L005354
BDB005354
|
BDBM129848
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cnc(O)c(Cl)c1)C2=O
|
C26H25Cl2N7O3 554.438000 |
QZMKRXNCNGDXOD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129848; PubChem:CID89715239
|
Local ready
Direct docking supported
|
|
E3L005355
BDB005355
|
BDBM129849
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CN(C)C(=O)N(C)C1)C2=O
|
C25H29ClN8O3 525.013000 |
ROYOOEDSXUZTAX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129849; PubChem:CID86766939
|
Local ready
Direct docking supported
|
|
E3L005356
BDB005356
|
BDBM129850
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CN(C)C(=O)N(C)C1)C2=O
|
C27H33ClN8O3 553.067000 |
MRCOWWDJETYBCS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129850; PubChem:CID86766940
|
Local ready
Direct docking supported
|
|
E3L005357
BDB005357
|
BDBM129851
COc1ccc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C30H23ClFN5O2 539.998000 |
GERLYFGVNAOEIU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129851; PubChem:CID86766941
|
Local ready
Direct docking supported
|
|
E3L005358
BDB005358
|
BDBM129852
COc1ncc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H25ClN6O2 537.023000 |
RZQOJXJIASBDHI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129852; PubChem:CID86766942
|
Local ready
Direct docking supported
|
|
E3L005359
BDB005359
|
BDBM129853
COc1ncc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H22ClFN6O2 540.986000 |
WRZQSDMOYZKSGB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129853; PubChem:CID86766943
|
Local ready
Direct docking supported
|
|
E3L005360
BDB005360
|
BDBM129854
COc1ncc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H22Cl2FN5O2 550.421000 |
FJJGHVXBAGOLIZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129854; PubChem:CID86766944
|
Local ready
Direct docking supported
|