| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005421
BDB005421
|
BDBM129916
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C30H27Cl2FN4O3 581.475000 |
HDXXIEYBJOZVKS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129916; PubChem:CID86766976
|
Local ready
Direct docking supported
|
|
E3L005422
BDB005422
|
BDBM129917
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C26H22Cl2FN5O3 542.398000 |
PLLKVLJFCLONMN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129917; PubChem:CID86766977
|
Local ready
Direct docking supported
|
|
E3L005423
BDB005423
|
BDBM129918
COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C27H22ClFN6O3 532.963000 |
IQYWWOVGZNKRNH-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129918; PubChem:CID71678097
|
Local ready
Direct docking supported
|
|
E3L005424
BDB005424
|
BDBM129919
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C30H29Cl2N5O4 594.499000 |
AYRHBAWMKWJMRJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129919; PubChem:CID86766978
|
Local ready
Direct docking supported
|
|
E3L005425
BDB005425
|
BDBM129920
COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H27Cl2N7O4 596.475000 |
JVTOZHREATWNCG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129920; PubChem:CID86766979
|
Local ready
Direct docking supported
|
|
E3L005426
BDB005426
|
BDBM129921
CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1
|
C26H25Cl2N7O3 554.438000 |
WYKUUMAEXJBREC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129921; PubChem:CID86766980
|
Local ready
Direct docking supported
|
|
E3L005427
BDB005427
|
BDBM129922
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C25H23Cl2N7O3 540.411000 |
UFQVQDSIDVRPAA-IBGZPJMESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129922; PubChem:CID86766981
|
Local ready
Direct docking supported
|
|
E3L005428
BDB005428
|
BDBM129923
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C25H23Cl2N7O3 540.411000 |
UFQVQDSIDVRPAA-LJQANCHMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129923; PubChem:CID71680111
|
Local ready
Direct docking supported
|
|
E3L005429
BDB005429
|
BDBM129924
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C26H24Cl2N6O2 523.424000 |
CYGATABVHKQRES-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129924; PubChem:CID71680112
|
Local ready
Direct docking supported
|
|
E3L005430
BDB005430
|
BDBM129925
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C26H24Cl2N6O2 523.424000 |
CYGATABVHKQRES-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129925; PubChem:CID86766982
|
Local ready
Direct docking supported
|
|
E3L005431
BDB005431
|
BDBM129926
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cncc(Cl)c1)C2=O
|
C29H27Cl2N5O3 564.473000 |
KSHVHIYZTYPPHF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129926; PubChem:CID86766983
|
Local ready
Direct docking supported
|
|
E3L005432
BDB005432
|
BDBM129927
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C26H22Cl2FN5O3 542.398000 |
MFKVIEVYLOJWSG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129927; PubChem:CID71680278
|
Local ready
Direct docking supported
|
|
E3L005433
BDB005433
|
BDBM129928
COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
OIHLWTJWGMLRKV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129928; PubChem:CID86766984
|
Local ready
Direct docking supported
|
|
E3L005434
BDB005434
|
BDBM129929
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2)C3=O)c(OC)n1
|
C26H23Cl2N5O3 524.408000 |
ABIXCDIFOVDPBV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129929; PubChem:CID86766985
|
Local ready
Direct docking supported
|
|
E3L005435
BDB005435
|
BDBM129930
COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1)C2=O
|
C28H22Cl2N4O2 517.416000 |
XPYVAUXJPWVVFW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129930; PubChem:CID86766986
|
Local ready
Direct docking supported
|
|
E3L005436
BDB005436
|
BDBM129932
COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1)C2=O
|
C33H32Cl2N4O4 619.549000 |
QQNALCFTOOSTNS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129932; PubChem:CID71680280
|
Local ready
Direct docking supported
|
|
E3L005437
BDB005437
|
BDBM129933
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(c2cccc(Cl)c2)C3=O)c(OC)n1
|
C27H25Cl2N5O3 538.435000 |
LKQMLLDUNCKLBG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129933; PubChem:CID86766987
|
Local ready
Direct docking supported
|
|
E3L005438
BDB005438
|
BDBM129934
COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1)C2=O
|
C29H24Cl2N4O2 531.443000 |
YSPQYIHQROIZFU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129934; PubChem:CID86766988
|
Local ready
Direct docking supported
|
|
E3L005439
BDB005439
|
BDBM129936
COc1ccc(C(=O)NCCO)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O4 607.538000 |
AMMRSBMBAHSSAG-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129936; PubChem:CID86766989
|
Local ready
Direct docking supported
|
|
E3L005440
BDB005440
|
BDBM129937
COc1ccc(C(=O)NCCO)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O4 607.538000 |
AMMRSBMBAHSSAG-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129937; PubChem:CID86766990
|
Local ready
Direct docking supported
|