| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007441
BDB007441
|
BDBM170371
CNC[C@@H](O)CCNC(=O)[C@@H]1N[C@H](CC(C)(C)C)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1ccc(F)c(Cl)c1
|
C28H34Cl2F2N4O3 583.507000 |
WDFCDLJQBVQULI-AXJGOAPESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170371
|
Local ready
Direct docking supported
|
|
E3L007442
BDB007442
|
BDBM170372
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCN(C(=O)CO)CC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C31H38Cl2FN5O4 634.580000 |
WMDCDRJSVJIQDI-QQZZJUGLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170372
|
Local ready
Direct docking supported
|
|
E3L007443
BDB007443
|
BDBM170373
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cncc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C26H31Cl2FN4O4 553.462000 |
DRIMAFXWWITGAX-GTJCPKOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170373
|
Local ready
Direct docking supported
|
|
E3L007444
BDB007444
|
BDBM170374
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cc(Cl)ccn2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C26H31Cl2FN4O4 553.462000 |
DDOZHOLPFKQAEQ-CRYDRMAXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170374
|
Local ready
Direct docking supported
|
|
E3L007445
BDB007445
|
BDBM170375
CC(C)(CCO)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C28H34Cl2FN3O5 582.500000 |
PCQRRVUHQZIMLN-FKUBJEGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170375
|
Local ready
Direct docking supported
|
|
E3L007446
BDB007446
|
BDBM170376
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CC2(CCO)CCCC2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C30H36Cl2FN3O5 608.538000 |
AAFJQQUWSZNMBT-OPMYFTJMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170376
|
Local ready
Direct docking supported
|
|
E3L007447
BDB007447
|
BDBM170377
O=C(NCC[C@H](O)CO)[C@H]1[C@H](c2cccc(Cl)c2)[C@@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]2CC3(CCCC3)CCN12
|
C30H34Cl2FN3O4 590.523000 |
DXMLPKPFMBVILL-OPMYFTJMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170377
|
Local ready
Direct docking supported
|
|
E3L007448
BDB007448
|
BDBM170378
CC[C@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C26H29Cl2FN4O3 535.447000 |
OKBIPZYWYPWAND-VUMQFKOGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170378; PubChem:CID58254294
|
Local ready
Direct docking supported
|
|
E3L007449
BDB007449
|
BDBM170379
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2ccc(F)c(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C27H31ClF3N3O4 554.009000 |
UXIBQHKZOWEBOT-LYAXWJQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170379
|
Local ready
Direct docking supported
|
|
E3L007450
BDB007450
|
BDBM170380
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C27H32ClF2N3O4 536.019000 |
VQEGFXQMFKVRFW-NVHWNKAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170380; PubChem:CID89770313
|
Local ready
Direct docking supported
|
|
E3L007451
BDB007451
|
BDBM170381
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C27H31ClF3N3O4 554.009000 |
ZHTQECJQWOMFTI-DUIWIZSASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170381
|
Local ready
Direct docking supported
|
|
E3L007452
BDB007452
|
BDBM170383
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(F)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C27H32F3N3O4 519.564000 |
LNRIBNIHPVEGRA-NVHWNKAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170383; PubChem:CID58254192
|
Local ready
Direct docking supported
|
|
E3L007453
BDB007453
|
BDBM170384
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2ccc(F)c(F)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C27H31F4N3O4 537.554000 |
RVSNGVUURYLGCO-LYAXWJQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170384; PubChem:CID58254420
|
Local ready
Direct docking supported
|
|
E3L007454
BDB007454
|
BDBM170386
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2ccc(F)c(Cl)c2)[C@@]12C(=O)Nc1cc(F)ccc12
|
C27H32ClF2N3O4 536.019000 |
IGICLMRIKAFWQP-NVHWNKAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170386; PubChem:CID89770314
|
Local ready
Direct docking supported
|
|
E3L007455
BDB007455
|
BDBM170387
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(F)ccc12
|
C27H33ClFN3O4 518.029000 |
YFGYLUBMLUNMRB-NXKDEWIBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170387; PubChem:CID89770407
|
Local ready
Direct docking supported
|
|
E3L007456
BDB007456
|
US9079913, MI-519-15-me
CN1[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]2(C(=O)Nc3cc(F)ccc32)[C@H]1CC(C)(C)C
|
C28H35ClFN3O4 532.056000 |
UXISGYQRMSDIJD-CPESNJHYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170388; PubChem:CID89770418
|
Local ready
Direct docking supported
|
|
E3L007457
BDB007457
|
US9079913, MI-219-M8
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCCO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C26H30Cl2FN3O3 522.448000 |
AHLYBKDOCLPCPH-SRCYTUNASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170389; PubChem:CID58254417
|
Local ready
Direct docking supported
|
|
E3L007458
BDB007458
|
BDBM170390
CC(C)(C)C[C@H]1N[C@@H](CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C23H25Cl2FN2O2 451.369000 |
XCRMMSPQWBXLBL-SRYPRDQNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170390; PubChem:CID58254206
|
Local ready
Direct docking supported
|
|
E3L007459
BDB007459
|
BDBM170391
CCCN1CCN(CCNC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)c(F)cc43)[C@H]2c2cccc(Cl)c2)CC1
|
C32H42Cl2FN5O2 618.625000 |
DMWNVBHSSYSUHN-IDSQFFPFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170391
|
Local ready
Direct docking supported
|
|
E3L007460
BDB007460
|
BDBM170393
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCC2CCC(O)C2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C30H36ClF2N3O3 560.085000 |
SSHNWZWLAACLAH-QCDXHFAXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170393
|
Local ready
Direct docking supported
|