| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L025701
BDB025701
|
US11319299, Example 87
C[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2ccc(F)cc2Cl)C[C@H](C)N1C
|
C28H31ClF2N6O2 557.045000 |
OHHYLCGVVMQZEM-HDICACEKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553037; PubChem:CID138541641
|
Local ready
Direct docking supported
|
|
E3L025702
BDB025702
|
US11319299, Example 88
C[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2cc(F)ccc2C(F)(F)F)C[C@H](C)N1C
|
C29H31F5N6O2 590.597000 |
BEDPKUFFMNDEMS-HDICACEKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553038; PubChem:CID137376898
|
Local ready
Direct docking supported
|
|
E3L025703
BDB025703
|
US11319299, Example 89
COc1cccc(C(=O)Nc2cc(-c3cnc(N4CCOCC4)nc3)c(F)cc2N2C[C@@H](C)N(C)[C@@H](C)C2)c1
|
C29H35FN6O3 534.636000 |
OOLSQXVQUZSLSY-BGYRXZFFSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553039; PubChem:CID137377064
|
Local ready
Direct docking supported
|
|
E3L025704
BDB025704
|
BDBM553040
COCCOc1ccc(-c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c(N3C[C@@H](C)N(C)[C@@H](C)C3)cc2F)cc1
|
C29H32F4N4O4 576.591000 |
LJEZKJONINXQKR-HDICACEKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553040; PubChem:CID137377108
|
Local ready
Direct docking supported
|
|
E3L025705
BDB025705
|
BDBM553041
CC(C)COc1ncc(-c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c(N3C[C@@H](C)N(C)[C@@H](C)C3)cc2F)cc1Cl
|
C29H32ClF4N5O3 610.052000 |
JJPSHYJTNCXTLD-CALCHBBNSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553041; PubChem:CID137376852
|
Local ready
Direct docking supported
|
|
E3L025706
BDB025706
|
BDBM553042
C[C@@H]1CN(c2cc(F)c(-c3ccc(OCC4CC4)c(Cl)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C30H31ClF4N4O3 607.048000 |
VUTVWOZKULFNRC-CALCHBBNSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553042; PubChem:CID137377178
|
Local ready
Direct docking supported
|
|
E3L025707
BDB025707
|
US11319299, Example 93
C[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2cn(C)c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C29H33F4N7O3 603.621000 |
NNAMONHIEIUUHG-HDICACEKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553043; PubChem:CID137376930
|
Local ready
Direct docking supported
|
|
E3L025708
BDB025708
|
BDBM553044
C[C@@H]1CN(c2cc(F)c(C3=CCOCC3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C25H28F4N4O3 508.516000 |
RRCYZJTZHOHODI-GASCZTMLSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553044; PubChem:CID137377118
|
Local ready
Direct docking supported
|
|
E3L025709
BDB025709
|
BDBM553045
C[C@@H]1CN(c2cc(F)c(C3=CCNCC3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C25H29F4N5O2 507.532000 |
AVGVTXDSLOVNKU-GASCZTMLSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553045; PubChem:CID137377198
|
Local ready
Direct docking supported
|
|
E3L025710
BDB025710
|
US11319299, Example 96
C[C@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2c[nH]nc2C(F)(F)F)CCN1C
|
C25H28F4N8O2 548.545000 |
RBCIHUVQKPTWLN-HNNXBMFYSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553046; PubChem:CID138551433
|
Local ready
Direct docking supported
|
|
E3L025711
BDB025711
|
US11319299, Example 97
Cc1cc(C(=O)Nc2cc(-c3cnc(N4CCOCC4)nc3)c(F)cc2N2CCN(C)[C@@H](C)C2)cc(C)c1F
|
C29H34F2N6O2 536.627000 |
QTPUIDDNZCGPCD-FQEVSTJZSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553047; PubChem:CID138551314
|
Local ready
Direct docking supported
|
|
E3L025712
BDB025712
|
BDBM553048
C[C@@H]1CN(c2cc(F)c(-c3cc(Cl)c(O)c(C#N)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C27H24ClF4N5O3 577.966000 |
ZNUVRQIZJMPPNN-OKILXGFUSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553048; PubChem:CID137376983
|
Local ready
Direct docking supported
|
|
E3L025713
BDB025713
|
BDBM553049
C[C@@H]1CN(c2cc(F)c(-c3cnc(OCc4ccccc4)c(C#N)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C33H30F4N6O3 634.634000 |
JHWNBLRQSVZFFV-BGYRXZFFSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553049; PubChem:CID137377132
|
Local ready
Direct docking supported
|
|
E3L025714
BDB025714
|
BDBM553050
C[C@@H]1CN(c2cc(F)c(-c3ccc(C#N)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C27H25F4N5O2 527.522000 |
IPEMJWWKLFCDAQ-IYBDPMFKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553050; PubChem:CID137377145
|
Local ready
Direct docking supported
|
|
E3L025715
BDB025715
|
BDBM553051
C[C@@H]1CN(c2cc(F)c(-c3ccc(OC4CCOCC4)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C30H33F4N5O4 603.617000 |
XNFQQDCHXNKZAL-HDICACEKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553051; PubChem:CID137376822
|
Local ready
Direct docking supported
|
|
E3L025716
BDB025716
|
BDBM553052
C[C@@H]1CN(c2cc(F)c(-c3cccc(C#N)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C27H25F4N5O2 527.522000 |
GQMOUZIVWHCVSC-IYBDPMFKSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553052; PubChem:CID137377063
|
Local ready
Direct docking supported
|
|
E3L025717
BDB025717
|
BDBM553053
C[C@@H]1CN(c2cc(F)c(-c3cnc(N(C)C)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C
|
C26H29F4N7O2 547.557000 |
YSPYPNXBAMLRAS-GASCZTMLSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553053; PubChem:CID137377211
|
Local ready
Direct docking supported
|
|
E3L025718
BDB025718
|
BDBM553054
COc1cc(-c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c(N3C[C@@H](C)N(C)[C@@H](C)C3)cc2F)cnc1OC
|
C27H29F4N5O4 563.552000 |
JYHUDMVMJYPMOG-GASCZTMLSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553054; PubChem:CID137377667
|
Local ready
Direct docking supported
|
|
E3L025719
BDB025719
|
US11319299, Example 105
C[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2cccc3c2OCO3)C[C@H](C)N1C
|
C29H33FN6O4 548.619000 |
FAJAAYYRXGYELC-KDURUIRLSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553055; PubChem:CID138541651
|
Local ready
Direct docking supported
|
|
E3L025720
BDB025720
|
US11319299, Example 106
COc1ccc(C(=O)Nc2cc(-c3cnc(N4CCOCC4)nc3)c(F)cc2N2C[C@@H](C)N(C)[C@@H](C)C2)cc1
|
C29H35FN6O3 534.636000 |
NSSDRFOXNAVQTL-BGYRXZFFSA-N | P61964 | WD repeat-containing protein 5 |
BindingDB, PubChem
BindingDB:BDBM553056; PubChem:CID138541931
|
Local ready
Direct docking supported
|