| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L003801
BDB003801
|
US20250388593, Example 5
CC(C)(C)OC(=O)Nc1cccc(-c2cn(C3CCCC(=O)NC3=O)nn2)c1
|
C19H23N5O4 385.424000 |
LMUHRNXTIQRZNM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87354; PubChem:CID171844082
|
Local ready
Direct docking supported
|
|
E3L003802
BDB003802
|
US20250388593, Example 6
CC(C)(C)OC(=O)Nc1ccccc1-c1cn(C2CCCC(=O)NC2=O)nn1
|
C19H23N5O4 385.424000 |
WTDOTEMLYSBESC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87355; PubChem:CID171844019
|
Local ready
Direct docking supported
|
|
E3L003803
BDB003803
|
BDBM87356
CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1ccc(Cl)cc1
|
C13H15ClN2O4S 330.793000 |
JSNFSKNNQYWNBK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87356; PubChem:CID171844096
|
Local ready
Direct docking supported
|
|
E3L003804
BDB003804
|
US20250388593, Example 8
O=C1CCCC(NS(=O)(=O)c2ccc(Cl)cc2)C(=O)N1
|
C12H13ClN2O4S 316.766000 |
CLCASNZGTALWCD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87357; PubChem:CID171844016
|
Local ready
Direct docking supported
|
|
E3L003805
BDB003805
|
US20250388593, Example 9
O=C1CCCC(NS(=O)(=O)c2cccc(Cl)c2)C(=O)N1
|
C12H13ClN2O4S 316.766000 |
ZOKQAEBEMBRNON-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87358; PubChem:CID171844126
|
Local ready
Direct docking supported
|
|
E3L003806
BDB003806
|
US20250388593, Example 10
CN(C1CCCC(=O)NC1=O)S(=O)(=O)c1cccc(Cl)c1
|
C13H15ClN2O4S 330.793000 |
HMHDHJTXLTYBIU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87359; PubChem:CID171844159
|
Local ready
Direct docking supported
|
|
E3L003807
BDB003807
|
US20250388593, Example 11
COC(=O)c1cccc(S(=O)(=O)N(C)C2CCCC(=O)NC2=O)c1
|
C15H18N2O6S 354.384000 |
VPEFFVLUSINTQQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87366; PubChem:CID177307327
|
Local ready
Direct docking supported
|
|
E3L003808
BDB003808
|
US20250388593, Example 12-2
O=C1COCC2(CCCN(C(=O)c3ccccc3)C2)C(=O)N1
|
C16H18N2O4 302.330000 |
PPWYBVBINJEZJC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87378; PubChem:CID171843967
|
Local ready
Direct docking supported
|
|
E3L003809
BDB003809
|
BDBM87431
CC(=O)Nc1ccc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)cc1
|
C19H21N3O3S 371.462000 |
WYBHFUAXFSOQRU-UHFFFAOYSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM87431; PubChem:CID1081265
|
Local ready
Direct docking supported
|
|
E3L003810
BDB003810
|
US20250388593, Example 13-2
O=C1COCC2(CCN(C(=O)c3ccccc3)CC2)C(=O)N1
|
C16H18N2O4 302.330000 |
UBJHUEOUEQTQBA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87534; PubChem:CID178289680
|
Local ready
Direct docking supported
|
|
E3L003811
BDB003811
|
US20250388593, Example 14
O=C1CCCC2(CCCN(C(=O)c3ccccc3)CCC2)C(=O)N1
|
C19H24N2O3 328.412000 |
ZMIHTNLXCUCFRO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87547; PubChem:CID177778509
|
Local ready
Direct docking supported
|
|
E3L003812
BDB003812
|
US20250388593, Example 15
CC(C)(C)OC(=O)c1ccc(N2CCCC3(COCC(=O)NC3=O)C2)nc1
|
C19H25N3O5 375.425000 |
PBIOMTMVRLQQQM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87583; PubChem:CID171843941
|
Local ready
Direct docking supported
|
|
E3L003813
BDB003813
|
US20250388593, Example 16
CC(C)(C)OC(=O)c1ccc(N2CCC3(CC2)COCC(=O)NC3=O)nc1
|
C19H25N3O5 375.425000 |
AVZRIRMKPHAQIJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87584; PubChem:CID171843974
|
Local ready
Direct docking supported
|
|
E3L003814
BDB003814
|
2-Phenyl-1,4-oxazepane-3,5-dione
O=C1CCOC(c2ccccc2)C(=O)N1
|
C11H11NO3 205.213000 |
RAUIOQJWYAKXEH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87585; PubChem:CID171843998
|
Local ready
Direct docking supported
|
|
E3L003815
BDB003815
|
US20250388593, Example 19
O=C1CCOC(c2cccc(Br)c2)C(=O)N1
|
C11H10BrNO3 284.109000 |
ZSQUSQBSLNEZEU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87586; PubChem:CID171844041
|
Local ready
Direct docking supported
|
|
E3L003816
BDB003816
|
N-(2,7-Dioxoazepan-3-yl)-N-methyl-3-phenylbenzamide
CN(C(=O)c1cccc(-c2ccccc2)c1)C1CCCC(=O)NC1=O
|
C20H20N2O3 336.391000 |
UBCDKBQAKZURGK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87587; PubChem:CID171844028
|
Local ready
Direct docking supported
|
|
E3L003817
BDB003817
|
US20250388593, Example 21
O=C1CCCC(NC(=O)c2cccc(-c3ccccc3)c2)C(=O)N1
|
C19H18N2O3 322.364000 |
VYADTGLHVIWDDH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87588; PubChem:CID177778531
|
Local ready
Direct docking supported
|
|
E3L003818
BDB003818
|
US20250388593, Example 22
O=C1COCC(NC(=O)c2cccc(-c3ccccc3)c2)C(=O)N1
|
C18H16N2O4 324.336000 |
LTWKQGDWUQVGTI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87783; PubChem:CID177778605
|
Local ready
Direct docking supported
|
|
E3L003819
BDB003819
|
US20250388593, Example 24
CC(C)(C)OC(=O)N(CC1CCCC(=O)NC1=O)c1ccc(F)cc1
|
C18H23FN2O4 350.390000 |
OOJFEDUEFZNJJK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87827; PubChem:CID171843970
|
Local ready
Direct docking supported
|
|
E3L003820
BDB003820
|
US20250388593, Example 25
O=C1CCCC(CNc2ccc(F)cc2)C(=O)N1
|
C13H15FN2O2 250.273000 |
XURSAOXRJFOVIH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM87901; PubChem:CID171843961
|
Local ready
Direct docking supported
|