| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L003841
BDB003841
|
US20250388593, Example 45
CC(C)(C)OC(=O)c1ccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)nc1
|
C21H24N4O6 428.445000 |
FRTFKWJYECPXBY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88440; PubChem:CID171843960
|
Local ready
Direct docking supported
|
|
E3L003842
BDB003842
|
US20250388593, Example 46
CC(C)(C)OC(=O)c1ccnc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)c1
|
C21H24N4O6 428.445000 |
SULFHTOAGBDWIL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88441; PubChem:CID177778580
|
Local ready
Direct docking supported
|
|
E3L003843
BDB003843
|
US20250388593, Example 47
CC(C)(C)OC(=O)c1cccc(N2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)n1
|
C21H24N4O6 428.445000 |
HZTYMIVXMUBJET-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88442; PubChem:CID177778538
|
Local ready
Direct docking supported
|
|
E3L003844
BDB003844
|
US20250388593, Example 48
CC(C)(C)OC(=O)CN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1
|
C17H23N3O6 365.386000 |
ZDRPNMFIRFZUQY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88443; PubChem:CID177778603
|
Local ready
Direct docking supported
|
|
E3L003845
BDB003845
|
US20250388593, Example 49
CC(C)(C)OC(=O)C(C)(C)N1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1
|
C19H27N3O6 393.440000 |
PFSXIMHJHKHFFU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88444; PubChem:CID177778502
|
Local ready
Direct docking supported
|
|
E3L003846
BDB003846
|
US20250388593, Example 50
CC(C)(C)OC(=O)NCCCCCN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1
|
C21H32N4O6 436.509000 |
RDEAWYQJHDBFLW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88445; PubChem:CID177778549
|
Local ready
Direct docking supported
|
|
E3L003847
BDB003847
|
US20250388593, Example 51
CC(C)(C)OC(=O)NCCCCCCCCN1CC2(CC(=O)N(C3CCC(=O)NC3=O)C2=O)C1
|
C24H38N4O6 478.590000 |
PZHCAYMCMMCGHJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88446; PubChem:CID177778559
|
Local ready
Direct docking supported
|
|
E3L003848
BDB003848
|
US20250388593, Example 52
CCOC(=O)c1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1
|
C21H20N4O6S 456.480000 |
KZZMPTKFLPFXHY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88447; PubChem:CID177778483
|
Local ready
Direct docking supported
|
|
E3L003849
BDB003849
|
US20250388593, Example 53
COC(=O)c1cccc(CN2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)c1
|
C20H21N3O6 399.403000 |
FLMFIHUDVLUOAR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88448; PubChem:CID177778526
|
Local ready
Direct docking supported
|
|
E3L003850
BDB003850
|
US20250388593, Example 54
COC(=O)c1ccc(CN2CC3(CC(=O)N(C4CCC(=O)NC4=O)C3=O)C2)cc1
|
C20H21N3O6 399.403000 |
JKKSSIXFCXQERZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88449; PubChem:CID177778560
|
Local ready
Direct docking supported
|
|
E3L003851
BDB003851
|
US20250388593, Example 55
O=C1CCC(N2C(=O)CC3(CN(C(=O)CNC(=O)c4ccccc4)C3)C2=O)C(=O)N1
|
C20H20N4O6 412.402000 |
VWYDPAXUGXKNIS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88450; PubChem:CID171843951
|
Local ready
Direct docking supported
|
|
E3L003852
BDB003852
|
US20250388593, Example 56
CC(C)(C)OC(=O)c1ccc(N2CCCC3(CCCC(=O)NC3=O)CCC2)nc1
|
C22H31N3O4 401.507000 |
ORFOUNMQGLWBNX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88452; PubChem:CID171844130
|
Local ready
Direct docking supported
|
|
E3L003853
BDB003853
|
N-[(2,7-Dioxoazepan-3-yl) methyl]benzamide
O=C1CCCC(CNC(=O)c2ccccc2)C(=O)N1
|
C14H16N2O3 260.293000 |
LBIOXQODMKOGTQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88454; PubChem:CID171844152
|
Local ready
Direct docking supported
|
|
E3L003854
BDB003854
|
US20250388593, Example 52
CCOC(=O)c1ccc2nc(N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)sc2c1
|
C21H20N4O6S 456.480000 |
KZZMPTKFLPFXHY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88455; PubChem:CID177778483
|
Local ready
Direct docking supported
|
|
E3L003855
BDB003855
|
tert-Butyl 3-(2,7-dioxoazepan-3-yl) benzoate
CC(C)(C)OC(=O)C1=CC(C2CCCC(=O)NC2=O)CC=C1
|
C17H23NO4 305.374000 |
ZVOVMWPGRSVFIB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88456; PubChem:CID178289681
|
Local ready
Direct docking supported
|
|
E3L003856
BDB003856
|
3-(4-Nitrophenyl) azepane-2,7-dione
O=C1CCCC(c2ccc([N+](=O)[O-])cc2)C(=O)N1
|
C12H12N2O4 248.238000 |
OYPIIJSKUMGOSW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88458; PubChem:CID171844033
|
Local ready
Direct docking supported
|
|
E3L003857
BDB003857
|
3-(3-Nitrophenyl) azepane-2,7-dione
O=C1CCCC(C2=CC([N+](=O)[O-])CC=C2)C(=O)N1
|
C12H14N2O4 250.254000 |
WXFRTFBUYNSEOJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88459; PubChem:CID178289682
|
Local ready
Direct docking supported
|
|
E3L003858
BDB003858
|
3-(2-Chloro-5-nitrophenyl) azepane-2,7-dione
O=C1CCCC(c2cc([N+](=O)[O-])ccc2Cl)C(=O)N1
|
C12H11ClN2O4 282.683000 |
VQCWCQSMLCAWEN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88460; PubChem:CID171844007
|
Local ready
Direct docking supported
|
|
E3L003859
BDB003859
|
US20250388593, Example 65
CC(=O)Nc1ccc(Cl)c(C2CCCC(=O)NC2=O)c1
|
C14H15ClN2O3 294.738000 |
CJQLSRZMIZUVBX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88461; PubChem:CID171844170
|
Local ready
Direct docking supported
|
|
E3L003860
BDB003860
|
BDBM88462
COC(=O)C(CCCCNC(=O)OCc1ccccc1)Oc1ccccc1[N+](=O)[O-]
|
C21H24N2O7 416.430000 |
DCHRNNVLHYSWCR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88462; PubChem:CID177307317
|
Local ready
Direct docking supported
|