| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L003881
BDB003881
|
US20250388593, Example 86
Nc1ccc(N2CCC3(CCCC(=O)NC3=O)C2)c(F)c1
|
C15H18FN3O2 291.326000 |
QPTLKDOBCXQMNM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88486; PubChem:CID177778598
|
Local ready
Direct docking supported
|
|
E3L003882
BDB003882
|
US20250388593, Example 87
CC(=O)Nc1ccc2nc(N3CCC4(CCCC(=O)NC4=O)C3)sc2c1
|
C18H20N4O3S 372.450000 |
FYMHPZVYCAPJHD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88489; PubChem:CID177778558
|
Local ready
Direct docking supported
|
|
E3L003883
BDB003883
|
US20250388593, Example 88
CC(=O)Nc1ccc(N2CCC3(CCCC(=O)NC3=O)C2)c(F)c1
|
C17H20FN3O3 333.363000 |
RJYJCZHUNRSWQK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88490; PubChem:CID177778584
|
Local ready
Direct docking supported
|
|
E3L003884
BDB003884
|
US20250388593, Example 89
CC(=O)N1CCN(Cc2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1
|
C21H29N5O3 399.495000 |
ITIQDOJGKCJAII-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88493; PubChem:CID171844006
|
Local ready
Direct docking supported
|
|
E3L003885
BDB003885
|
US20250388593, Example 90-1
CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2)nc1
|
C19H25N3O4 359.426000 |
RJKWCFDTMAGAGJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88494; PubChem:CID171843937
|
Local ready
Direct docking supported
|
|
E3L003886
BDB003886
|
US20250388593, Example 90-2
CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2=O)nc1
|
C19H23N3O5 373.409000 |
UHCXIOLRBMVBSJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88495; PubChem:CID171844145
|
Local ready
Direct docking supported
|
|
E3L003887
BDB003887
|
US20250388593, Example 91
CC(C)(C)OC(=O)c1ccnc(N2CCC3(CCCC(=O)NC3=O)C2)c1
|
C19H25N3O4 359.426000 |
CKHMICNOAOPMDO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88496; PubChem:CID171844146
|
Local ready
Direct docking supported
|
|
E3L003888
BDB003888
|
US20250388593, Example 92
CC(C)(C)OC(=O)c1cccc(N2CCC3(CCCC(=O)NC3=O)C2)n1
|
C19H25N3O4 359.426000 |
HXUVHGIEQXTHIA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88497; PubChem:CID171844079
|
Local ready
Direct docking supported
|
|
E3L003889
BDB003889
|
US20250388593, Example 93
CC(C)(C)OC(=O)c1ccc(N2CCCC3(CCCC(=O)NC3=O)C2)nc1
|
C20H27N3O4 373.453000 |
ONWARMZJYDVOFB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88499; PubChem:CID171843952
|
Local ready
Direct docking supported
|
|
E3L003890
BDB003890
|
US20250388593, Example 94
CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)CC2)nc1
|
C20H27N3O4 373.453000 |
GZANGONEPGSRCG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88504; PubChem:CID171843933
|
Local ready
Direct docking supported
|
|
E3L003891
BDB003891
|
US20250388593, Example 95
CC(C)(C)OC(=O)c1cnc(N2CCC3(CCCC(=O)NC3=O)C2)s1
|
C17H23N3O4S 365.455000 |
KCYSOSNBOOSDCQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88505; PubChem:CID171843953
|
Local ready
Direct docking supported
|
|
E3L003892
BDB003892
|
US20250388593, Example 96
CNC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)C2)nc1
|
C16H20N4O3 316.361000 |
ZBLMYXWGILWIIX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88506; PubChem:CID171843966
|
Local ready
Direct docking supported
|
|
E3L003893
BDB003893
|
US20250388593, Example 97
CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1
|
C24H33N5O5 471.558000 |
RSKYYMBEWKGYNQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88507; PubChem:CID171844162
|
Local ready
Direct docking supported
|
|
E3L003894
BDB003894
|
US20250388593, Example 98
CC(C)(C)OC(=O)N1CCN(C(=O)CN2CCC3(CCCC(=O)NC3=O)CC2=O)CC1
|
C21H32N4O6 436.509000 |
HDLHOBPPOQTVSJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88508; PubChem:CID171844044
|
Local ready
Direct docking supported
|
|
E3L003895
BDB003895
|
US20250388593, Example 99
CC(C)(C)OC(=O)N1CCN(Cc2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1
|
C24H35N5O4 457.575000 |
NBJZYOQDHPXRLX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88509; PubChem:CID171844037
|
Local ready
Direct docking supported
|
|
E3L003896
BDB003896
|
2-Benzoyl-2,8-diazaspiro [5.6]dodecane-7,9-dione
O=C1CCCC2(CCCN(C(=O)c3ccccc3)C2)C(=O)N1
|
C17H20N2O3 300.358000 |
UUWCUFXINSQNDG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88510; PubChem:CID171844064
|
Local ready
Direct docking supported
|
|
E3L003897
BDB003897
|
3-Benzoyl-3,8-diazaspiro [5.6]dodecane-7,9-dione
O=C1CCCC2(CCN(C(=O)c3ccccc3)CC2)C(=O)N1
|
C17H20N2O3 300.358000 |
DTOPKLYQQDJIHD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88511; PubChem:CID171844068
|
Local ready
Direct docking supported
|
|
E3L003898
BDB003898
|
US20250388593, Example 107
CC(C)(C)OC(=O)CN1CCC2(CCCC(=O)NC2=O)CC1=O
|
C16H24N2O5 324.377000 |
BUEKFKCILYOXKL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88512; PubChem:CID171844100
|
Local ready
Direct docking supported
|
|
E3L003899
BDB003899
|
US20250388593, Example 108
CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)nc1
|
C20H25N3O5 387.436000 |
PWSUHPWXNIIJIQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88513; PubChem:CID171843978
|
Local ready
Direct docking supported
|
|
E3L003900
BDB003900
|
US20250388593, Example 109
CC(C)(C)OC(=O)c1ccc(N2CCC3(CCCC(=O)NC3=O)CC2=O)cc1
|
C21H26N2O5 386.448000 |
ONWGEIMUOXTXBN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM88514; PubChem:CID171844023
|
Local ready
Direct docking supported
|