| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005381
BDB005381
|
BDBM129875
COc1ccc(CC(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C31H29Cl2FN4O3 595.502000 |
XPLGYKPBWAJRTH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129875; PubChem:CID71679598
|
Local ready
Direct docking supported
|
|
E3L005382
BDB005382
|
BDBM129876
COC[C@H](C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C28H27Cl2N5O4 568.461000 |
TWAINRRINSLNFG-GZWBLTSWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129876; PubChem:CID86766956
|
Local ready
Direct docking supported
|
|
E3L005383
BDB005383
|
BDBM129877
CNC(=O)Cc1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
|
C30H27Cl2FN4O3 581.475000 |
YUUMNVUHOZNLNE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129877; PubChem:CID86766957
|
Local ready
Direct docking supported
|
|
E3L005384
BDB005384
|
BDBM129878
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cnc1O)C2=O
|
C26H25Cl2N7O3 554.438000 |
VBXBHPIMLUTTLN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129878; PubChem:CID71679599
|
Local ready
Direct docking supported
|
|
E3L005385
BDB005385
|
BDBM129879
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C25H23Cl2N7O3 540.411000 |
UFQVQDSIDVRPAA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129879; PubChem:CID71679600
|
Local ready
Direct docking supported
|
|
E3L005386
BDB005386
|
BDBM129880
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H27ClN8O3 559.030000 |
YNFVSWHRMQTJHZ-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129880; PubChem:CID86766958
|
Local ready
Direct docking supported
|
|
E3L005387
BDB005387
|
BDBM129881
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C28H27ClN8O3 559.030000 |
YNFVSWHRMQTJHZ-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129881; PubChem:CID86766959
|
Local ready
Direct docking supported
|
|
E3L005388
BDB005388
|
BDBM129882
COc1ccc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H24Cl2FN3O4 568.432000 |
YUSJOHFHBXWXSP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129882; PubChem:CID71679601
|
Local ready
Direct docking supported
|
|
E3L005389
BDB005389
|
BDBM129883
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)cnc1O)C2=O
|
C26H25Cl2N7O3 554.438000 |
VBXBHPIMLUTTLN-HXUWFJFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129883; PubChem:CID89715017
|
Local ready
Direct docking supported
|
|
E3L005390
BDB005390
|
BDBM129884
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)cnc1O)C2=O
|
C26H25Cl2N7O3 554.438000 |
VBXBHPIMLUTTLN-FQEVSTJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129884; PubChem:CID89715231
|
Local ready
Direct docking supported
|
|
E3L005391
BDB005391
|
BDBM129885
COC(=O)Cc1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
|
C30H26Cl2FN3O4 582.459000 |
CTWCQSSDKLCXDT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129885; PubChem:CID71679602
|
Local ready
Direct docking supported
|
|
E3L005392
BDB005392
|
BDBM129886
COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C27H22ClFN6O3 532.963000 |
IQYWWOVGZNKRNH-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129886; PubChem:CID71679761
|
Local ready
Direct docking supported
|
|
E3L005393
BDB005393
|
BDBM129887
COc1ncc(-c2nc3c(n2C(C)C)[C@@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H25Cl2N5O3 538.435000 |
SDGHDCDOONCQMU-JOCHJYFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129887; PubChem:CID86766960
|
Local ready
Direct docking supported
|
|
E3L005394
BDB005394
|
BDBM129888
COc1ncc(-c2nc3c(n2C(C)C)[C@H](c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H25Cl2N5O3 538.435000 |
SDGHDCDOONCQMU-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129888; PubChem:CID86766961
|
Local ready
Direct docking supported
|
|
E3L005395
BDB005395
|
BDBM129889
COc1cnc(C#N)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C27H22Cl2N6O2 533.419000 |
TWQAHQGAIWCVQZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129889; PubChem:CID86766962
|
Local ready
Direct docking supported
|
|
E3L005396
BDB005396
|
BDBM129890
COc1cnc(N(C)C)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C27H25Cl2FN6O2 555.441000 |
LXBXYZLFDBLELV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129890; PubChem:CID71679762
|
Local ready
Direct docking supported
|
|
E3L005397
BDB005397
|
BDBM129891
COc1cnc(N(C)C)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C28H28Cl2N6O2 551.478000 |
ZYWOMCZQMYDUQF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129891; PubChem:CID86766963
|
Local ready
Direct docking supported
|
|
E3L005398
BDB005398
|
BDBM129892
COc1ccc(C(N)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C28H23Cl2FN4O3 553.421000 |
GCUNSJLFRSLNMB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129892; PubChem:CID71679763
|
Local ready
Direct docking supported
|
|
E3L005399
BDB005399
|
BDBM129893
COc1ccc(C(N)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H23Cl2FN4O3 553.421000 |
FPZAXIDNSDUVHJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129893; PubChem:CID89720046
|
Local ready
Direct docking supported
|
|
E3L005400
BDB005400
|
BDBM129894
COc1ccc(C(N)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C29H26Cl2N4O3 549.458000 |
LNDPMEJTVLCCHE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129894; PubChem:CID86766964
|
Local ready
Direct docking supported
|