| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005361
BDB005361
|
BDBM129855
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H22ClFN6O2 540.986000 |
JSRNNPIFXLIKLR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129855; PubChem:CID86766945
|
Local ready
Direct docking supported
|
|
E3L005362
BDB005362
|
BDBM129856
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H25ClN6O2 537.023000 |
ACEGVIRLYYSHCR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129856; PubChem:CID86766946
|
Local ready
Direct docking supported
|
|
E3L005363
BDB005363
|
BDBM129857
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H22Cl2FN5O2 550.421000 |
ZKMWZPFDSPCJMI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129857; PubChem:CID71679442
|
Local ready
Direct docking supported
|
|
E3L005364
BDB005364
|
BDBM129858
CCOC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
|
C32H30ClN5O4 584.076000 |
ZIFLFKDGLAKUMD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129858; PubChem:CID71679443
|
Local ready
Direct docking supported
|
|
E3L005365
BDB005365
|
BDBM129859
COc1cnc(C(N)=O)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C27H24Cl2N6O3 551.434000 |
AJSOHRMOHHOVFH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129859; PubChem:CID86766947
|
Local ready
Direct docking supported
|
|
E3L005366
BDB005366
|
BDBM129860
COc1ncc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H23Cl2FN4O4 569.420000 |
NDWNTOUUHSIIPV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129860; PubChem:CID86766948
|
Local ready
Direct docking supported
|
|
E3L005367
BDB005367
|
BDBM129861
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cnc(O)c(Cl)c2)C3=O)c(OC)n1
|
C25H22Cl2N6O4 541.395000 |
NBNSNCCQKFNTSI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129861; PubChem:CID89719965
|
Local ready
Direct docking supported
|
|
E3L005368
BDB005368
|
BDBM129862
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C26H21ClFN7O2 517.952000 |
FELBVMGPWDVNJS-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129862; PubChem:CID86766949
|
Local ready
Direct docking supported
|
|
E3L005369
BDB005369
|
BDBM129863
COc1nc(N)ncc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O
|
C26H21ClFN7O2 517.952000 |
FELBVMGPWDVNJS-OAQYLSRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129863; PubChem:CID86766950
|
Local ready
Direct docking supported
|
|
E3L005370
BDB005370
|
BDBM129864
Cc1nc(-c2cccc(-c3nc4c(n3C(C)C)C(c3ccc(Cl)cc3)N(c3cc(Cl)ccc3C)C4=O)c2)c[nH]1
|
C31H27Cl2N5O 556.497000 |
DPBKTMYFTUQWIW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129864; PubChem:CID89720203
|
Local ready
Direct docking supported
|
|
E3L005371
BDB005371
|
BDBM129865
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CN(C)C(=O)N(C)C2)C3=O)c(OC)n1
|
C26H30ClN7O4 540.024000 |
VHLPRULBEFEIGL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129865; PubChem:CID71679444
|
Local ready
Direct docking supported
|
|
E3L005372
BDB005372
|
BDBM129866
COc1ncc(CC(=O)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C30H26ClN5O4 556.022000 |
GWFCRMWCBGIQLL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129866; PubChem:CID86707778
|
Local ready
Direct docking supported
|
|
E3L005373
BDB005373
|
BDBM129867
CNC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
|
C29H26Cl2FN5O3 582.463000 |
UQCQXTZYOAYBEC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129867; PubChem:CID71679445
|
Local ready
Direct docking supported
|
|
E3L005374
BDB005374
|
BDBM129868
CNC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c1
|
C30H26ClFN6O3 573.028000 |
WXGRZRGNIWVZLN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129868; PubChem:CID86766951
|
Local ready
Direct docking supported
|
|
E3L005375
BDB005375
|
BDBM129869
COc1ncc(-c2nc3c(n2[C@@H](C)CO)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H25Cl2N5O4 554.434000 |
YPDNCAWNHQIVIG-UEDXYCIISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129869; PubChem:CID71679446
|
Local ready
Direct docking supported
|
|
E3L005376
BDB005376
|
BDBM129870
CCOC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cccc(Cl)c2F)C3=O)c1
|
C31H27ClFN5O4 588.039000 |
RNUMPJLPEXXPKI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129870; PubChem:CID86766952
|
Local ready
Direct docking supported
|
|
E3L005377
BDB005377
|
BDBM129871
CNC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
|
C31H29ClN6O3 569.065000 |
CHFDCRYERMGCLR-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM129871
|
Local ready
Direct docking supported
|
|
E3L005378
BDB005378
|
BDBM129872
CCOC(=O)Cc1cnc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)c1
|
C30H27Cl2FN4O4 597.474000 |
ZDSVEZCAFVGDAQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129872; PubChem:CID86766953
|
Local ready
Direct docking supported
|
|
E3L005379
BDB005379
|
BDBM129873
COc1ncc(-c2nc3c(n2C(C)C)C(C)(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C29H29Cl2N5O3 566.489000 |
IVFVAIZFSWHLQW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129873; PubChem:CID86766954
|
Local ready
Direct docking supported
|
|
E3L005380
BDB005380
|
BDBM129874
CNC(=O)Cc1ccc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
|
C31H30Cl2N4O3 577.512000 |
XROKMIHRKYVNBF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129874; PubChem:CID86766955
|
Local ready
Direct docking supported
|