| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005401
BDB005401
|
BDBM129895
CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1
|
C25H23Cl2N7O3 540.411000 |
LPKZQLVOSNFBCP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129895; PubChem:CID89714844
|
Local ready
Direct docking supported
|
|
E3L005402
BDB005402
|
BDBM129896
CNc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1
|
C25H23Cl2N7O3 540.411000 |
LPKZQLVOSNFBCP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129896; PubChem:CID89714844
|
Local ready
Direct docking supported
|
|
E3L005403
BDB005403
|
BDBM129898
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)c(=O)n(C)c1=O)C2=O
|
C27H29ClN8O4 565.034000 |
HXHBHQAZNMPLLS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129898; PubChem:CID89720214
|
Local ready
Direct docking supported
|
|
E3L005404
BDB005404
|
BDBM129899
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cn(C)c(=O)n(C)c1=O)C2=O
|
C25H25ClN8O4 536.980000 |
JFTRUOHAIVFOBK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129899; PubChem:CID89720331
|
Local ready
Direct docking supported
|
|
E3L005405
BDB005405
|
BDBM129900
COc1ncc(-c2nc3c(n2C2CC2)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C27H23Cl2N5O3 536.419000 |
WTHHEODNHKNNKI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129900; PubChem:CID71679765
|
Local ready
Direct docking supported
|
|
E3L005406
BDB005406
|
BDBM129901
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2C)N(c2cccc(Cl)c2F)C3=O)c(OC)n1
|
C28H24ClFN6O3 546.990000 |
UKGMHMLILGYNRY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129901; PubChem:CID86766969
|
Local ready
Direct docking supported
|
|
E3L005407
BDB005407
|
BDBM129902
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C29H24ClFN4O2 514.988000 |
ACCLSHZNFVKRDJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129902; PubChem:CID86766970
|
Local ready
Direct docking supported
|
|
E3L005408
BDB005408
|
BDBM129903
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C27H25Cl2FN6O2 555.441000 |
FDIKWCUCPNYGCA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129903; PubChem:CID71679931
|
Local ready
Direct docking supported
|
|
E3L005409
BDB005409
|
BDBM129904
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C27H25Cl2FN6O2 555.441000 |
MTHWLSLOWNKVRL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129904; PubChem:CID86766971
|
Local ready
Direct docking supported
|
|
E3L005410
BDB005410
|
BDBM129905
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C33H32ClN5O3 582.104000 |
MMIUUIWBVMXTTG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129905; PubChem:CID71679932
|
Local ready
Direct docking supported
|
|
E3L005411
BDB005411
|
BDBM129906
CCn1cc(OC)c(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)cc1=O
|
C30H28ClN5O3 542.039000 |
PTZOIKDDGVFZHU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129906; PubChem:CID86766972
|
Local ready
Direct docking supported
|
|
E3L005412
BDB005412
|
BDBM129907
COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(C#N)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C29H27ClN6O3 543.027000 |
MOLXVXMZBSTFPY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129907; PubChem:CID71679933
|
Local ready
Direct docking supported
|
|
E3L005413
BDB005413
|
BDBM129908
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C31H30Cl2N4O3 577.512000 |
IFVDWMMHXKFNKA-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129908; PubChem:CID86766973
|
Local ready
Direct docking supported
|
|
E3L005414
BDB005414
|
BDBM129909
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O
|
C31H30Cl2N4O3 577.512000 |
IFVDWMMHXKFNKA-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129909; PubChem:CID71679934
|
Local ready
Direct docking supported
|
|
E3L005415
BDB005415
|
BDBM129910
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H27ClN4O2 511.025000 |
HLFMWRMGCDUPRC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129910; PubChem:CID71679935
|
Local ready
Direct docking supported
|
|
E3L005416
BDB005416
|
BDBM129911
COc1nc(N)ncc1C1=NC2C(=O)N(c3cccc(Cl)c3F)C(c3ccc(Cl)cc3)C2N1C(C)C
|
C25H23Cl2FN6O2 529.403000 |
WQOKGGNJPHAUGI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129911; PubChem:CID86766974
|
Local ready
Direct docking supported
|
|
E3L005417
BDB005417
|
BDBM129912
COc1nc(N)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C25H21Cl2FN6O2 527.387000 |
XCYXFLGIXMWOGQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129912; PubChem:CID71680108
|
Local ready
Direct docking supported
|
|
E3L005418
BDB005418
|
BDBM129913
COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C28H21Cl2FN4O2 535.406000 |
VMBMBKAFWBLORZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129913; PubChem:CID86766975
|
Local ready
Direct docking supported
|
|
E3L005419
BDB005419
|
BDBM129914
COc1ccc(C(=O)N2CCOCC2)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C32H29Cl2FN4O4 623.512000 |
OYBSFSGSCZKAIH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129914; PubChem:CID71680109
|
Local ready
Direct docking supported
|
|
E3L005420
BDB005420
|
BDBM129915
COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C27H27Cl2N7O3 568.465000 |
MLVQWIAMCUTJAS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129915; PubChem:CID71680110
|
Local ready
Direct docking supported
|