| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L001341
BDB001341
|
2-phenoxybenzoyltryptophan derivative, R1C3
O=C(N[C@@H](Cc1cn(C(=O)OCc2ccccc2)c2cc(Br)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C32H25BrN2O6 613.464000 |
JICQRQRHNNITKK-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31209; PubChem:CID44176144
|
Local ready
Direct docking supported
|
|
E3L001342
BDB001342
|
2-phenoxybenzoyltryptophan derivative, R1C4
O=C(N[C@@H](Cc1cn(Cc2ccc(OCc3ccccc3)cc2)c2cc(Br)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C38H31BrN2O5 675.579000 |
SBDSDIMVYOUEEB-UMSFTDKQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31210; PubChem:CID44176145
|
Local ready
Direct docking supported
|
|
E3L001343
BDB001343
|
2-phenoxybenzoyltryptophan derivative, R2C1
O=C(N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C24H19ClN2O4 434.879000 |
LZLFTWKFCUCQAY-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31211; PubChem:CID44176146
|
Local ready
Direct docking supported
|
|
E3L001344
BDB001344
|
2-phenoxybenzoyltryptophan derivative, R2C2
O=C(N[C@@H](Cc1cn(C(=O)CCC2CCCC2)c2cc(Cl)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C32H31ClN2O5 559.062000 |
HNCXCBGJHZVXBL-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31212; PubChem:CID44176147
|
Local ready
Direct docking supported
|
|
E3L001345
BDB001345
|
2-phenoxybenzoyltryptophan derivative, R2C3
O=C(N[C@@H](Cc1cn(C(=O)OCc2ccccc2)c2cc(Cl)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C32H25ClN2O6 569.013000 |
USVVJMSKOUQARY-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31213; PubChem:CID44176148
|
Local ready
Direct docking supported
|
|
E3L001346
BDB001346
|
2-phenoxybenzoyltryptophan derivative, R2C4
O=C(N[C@@H](Cc1cn(Cc2ccc(OCc3ccccc3)cc2)c2cc(Cl)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C38H31ClN2O5 631.128000 |
OYOSGWRVZVTWQM-UMSFTDKQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31214; PubChem:CID44176149
|
Local ready
Direct docking supported
|
|
E3L001347
BDB001347
|
2-phenoxybenzoyltryptophan derivative, R3C1
O=C(N[C@@H](Cc1c[nH]c2cc(F)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C24H19FN2O4 418.424000 |
XZCDKMHIEHVAFO-NRFANRHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31215; PubChem:CID44176150
|
Local ready
Direct docking supported
|
|
E3L001348
BDB001348
|
2-phenoxybenzoyltryptophan derivative, R3C2
O=C(N[C@@H](Cc1cn(C(=O)CCC2CCCC2)c2cc(F)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C32H31FN2O5 542.607000 |
JZXQQRRUFQSGQM-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31216; PubChem:CID44176151
|
Local ready
Direct docking supported
|
|
E3L001349
BDB001349
|
2-phenoxybenzoyltryptophan derivative, R3C3
O=C(N[C@@H](Cc1cn(C(=O)OCc2ccccc2)c2cc(F)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C32H25FN2O6 552.558000 |
JTDAJTALRFKEKO-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31217; PubChem:CID44176152
|
Local ready
Direct docking supported
|
|
E3L001350
BDB001350
|
2-phenoxybenzoyltryptophan derivative, R3C4
O=C(N[C@@H](Cc1cn(Cc2ccc(OCc3ccccc3)cc2)c2cc(F)ccc12)C(=O)O)c1ccccc1Oc1ccccc1
|
C38H31FN2O5 614.673000 |
IZVAHDQNVPJZPA-UMSFTDKQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31218; PubChem:CID44176153
|
Local ready
Direct docking supported
|
|
E3L001351
BDB001351
|
2-phenoxybenzoyltryptophan derivative, R4C1
N#Cc1ccc2[nH]cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(=O)O)c2c1
|
C25H19N3O4 425.444000 |
RNMJHKQPDFCCQA-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31219; PubChem:CID44176154
|
Local ready
Direct docking supported
|
|
E3L001352
BDB001352
|
2-phenoxybenzoyltryptophan derivative, R4C2
N#Cc1ccc2c(c1)c(C[C@H](NC(=O)c1ccccc1Oc1ccccc1)C(=O)O)cn2C(=O)CCC1CCCC1
|
C33H31N3O5 549.627000 |
WVWRTZSRPMGSGO-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31220; PubChem:CID44176155
|
Local ready
Direct docking supported
|
|
E3L001353
BDB001353
|
2-phenoxybenzoyltryptophan derivative, R4C3
N#Cc1ccc2c(c1)c(C[C@H](NC(=O)c1ccccc1Oc1ccccc1)C(=O)O)cn2C(=O)OCc1ccccc1
|
C33H25N3O6 559.578000 |
ARBOSHRAOXVNJA-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31221; PubChem:CID44176156
|
Local ready
Direct docking supported
|
|
E3L001354
BDB001354
|
2-phenoxybenzoyltryptophan derivative, R4C4
N#Cc1ccc2c(c1)c(C[C@H](NC(=O)c1ccccc1Oc1ccccc1)C(=O)O)cn2Cc1ccc(OCc2ccccc2)cc1
|
C39H31N3O5 621.693000 |
AOWLHPAIWPBAAQ-DHUJRADRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31222; PubChem:CID44176157
|
Local ready
Direct docking supported
|
|
E3L001355
BDB001355
|
2-phenoxybenzoyltryptophan derivative, R5C1
Cc1ccc2[nH]cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(=O)O)c2c1
|
C25H22N2O4 414.461000 |
WGSQKPIUJIOGOT-QFIPXVFZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31223; PubChem:CID44176158
|
Local ready
Direct docking supported
|
|
E3L001356
BDB001356
|
2-phenoxybenzoyltryptophan derivative, R5C2
Cc1ccc2c(c1)c(C[C@H](NC(=O)c1ccccc1Oc1ccccc1)C(=O)O)cn2C(=O)CCC1CCCC1
|
C33H34N2O5 538.644000 |
XLDQLWPXGSTAGS-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31224; PubChem:CID44176159
|
Local ready
Direct docking supported
|
|
E3L001357
BDB001357
|
2-phenoxybenzoyltryptophan derivative, R5C3
Cc1ccc2c(c1)c(C[C@H](NC(=O)c1ccccc1Oc1ccccc1)C(=O)O)cn2C(=O)OCc1ccccc1
|
C33H28N2O6 548.595000 |
FHNQOOZTZWBWQO-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31225; PubChem:CID44176160
|
Local ready
Direct docking supported
|
|
E3L001358
BDB001358
|
2-phenoxybenzoyltryptophan derivative, R5C4
Cc1ccc2c(c1)c(C[C@H](NC(=O)c1ccccc1Oc1ccccc1)C(=O)O)cn2Cc1ccc(OCc2ccccc2)cc1
|
C39H34N2O5 610.710000 |
YJHXKFJZIRNVRS-DHUJRADRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31226; PubChem:CID44176161
|
Local ready
Direct docking supported
|
|
E3L001359
BDB001359
|
Isoindolinone scaffold, 13
CC(C)(C)c1ccc(COC2(c3ccccc3)c3ccccc3C(=O)N2Cc2ccccc2)cc1
|
C32H31NO2 461.605000 |
VBLCHDNBGBWZBP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31227; PubChem:CID16090434
|
Local ready
Direct docking supported
|
|
E3L001360
BDB001360
|
Isoindolinone scaffold, 14
CCCOC1(c2ccccc2)c2ccccc2C(=O)N1C(Cc1ccc(O)cc1)C(=O)OC
|
C27H27NO5 445.515000 |
CYRRIZADGIHBIE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31228; PubChem:CID16090384
|
Local ready
Direct docking supported
|